Protein Overview: ASCL3_MOUSE

General Information:
Name(s) found:	ASCL3_MOUSE [Swiss-Prot]
Description(s) found: Found 32 descriptions. SHOW ALL	Achaete-scute homolog 3 OS=Mus musculus GN=Ascl3 PE=2 SV=1 [Swiss-Prot]
Organism:	Mus musculus
Length:	174 amino acids
Gene Ontology:
Cellular Component:	nucleus [IDA] transcription factor complex [IPI]
Biological Process:	transcription [IEA] regulation of transcription [IEA] regulation of transcription from RNA polymerase II promoter [IDA]
Molecular Function:	DNA binding [IDA] protein binding [IPI] transcription regulator activity [IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDTRSYPSPP DRLSVFAESA HLPLSRPFYL DPMVTVHLCP ETPVPASYTD ELPLLPFSSD  60
   61 TLIMNNYGDP YPFPFPMPYT NYRRCDYTYG PAFIRKRNER ERQRVKCVNE GYARLRRHLP 120
  121 EDYLEKRLSK VETLRAAIKY ISYLQSLLYP DESETKKNPR TASCGSLDPA LRVI

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..83]	deduced	N/A	No confident structure predictions are available.
2	View Details	[84..174]	PSI-BLAST	14.09691	Myc prot-oncogene protein

Functions predicted (by domain):

#

Gene Ontology predictions

1

No functions predicted.

2

Term	Confidence	Notes
transcription regulator activity	5.38658950816179	bayes_pls_golite062009
DNA binding	5.18654839258297	bayes_pls_golite062009
nucleic acid binding	5.05768805749761	bayes_pls_golite062009
transcription factor activity	4.78039531631248	bayes_pls_golite062009
binding	3.81829206350975	bayes_pls_golite062009
RNA polymerase II transcription factor activity	3.39500382187264	bayes_pls_golite062009
transcription factor binding	2.61163564741984	bayes_pls_golite062009
transcription activator activity	2.5495467409976	bayes_pls_golite062009
RNA polymerase II transcription factor activity, enhancer binding	2.42306484786159	bayes_pls_golite062009
sequence-specific DNA binding	2.31910036997977	bayes_pls_golite062009
protein binding	1.59929864805879	bayes_pls_golite062009
promoter binding	1.56457725225443	bayes_pls_golite062009
transcription cofactor activity	1.52770895937238	bayes_pls_golite062009
transcription coactivator activity	1.39260472877067	bayes_pls_golite062009
transcription repressor activity	0.955588849035129	bayes_pls_golite062009
transcription corepressor activity	0.801830750183111	bayes_pls_golite062009
structure-specific DNA binding	0.3655541712365	bayes_pls_golite062009
double-stranded DNA binding	0.29436315000437	bayes_pls_golite062009

Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Source: Reynolds et al. (2008)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle