Protein Overview: FOXA1_MOUSE

General Information:
Name(s) found:	FOXA1_MOUSE [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|94392739\|ref\|XP_999351.1\| PREDICTED: similar to Hepatocyte nuclear factor 3-alpha (HNF-3A) (Forkhead box protein A1) [Mus musculus] [NCBI NR] gi\|66793398\|ref\|NP_032285.2\| forkhead box A1 [Mus musculus] [NCBI NR] gi\|66396602\|gb\|AAH96524.1\| Forkhead box A1 [Mus musculus] [NCBI NR] gi\|2506414\|sp\|P35582.2\|FOXA1_MOUSE RecName: Full=Hepatocyte nuclear factor 3-alpha; Short=HNF-3-alpha; Short=HNF-3A; AltName: Full=Forkhead box protein A1 [NCBI NR] gi\|149263107\|ref\|XP_001478326.1\| PREDICTED: similar to Hepatocyte nuclear factor 3-alpha (HNF-3A) (Forkhead box protein A1) [Mus musculus] [NCBI NR] Hepatocyte nuclear factor 3-alpha - Mus musculus (Mouse) [Swiss-Prot] (P35582) Hepatocyte nuclear factor 3-alpha (HNF-3A) (Forkhead box protein A1) [Swiss-Prot] Hepatocyte nuclear factor 3-alpha OS=Mus musculus GN=Foxa1 PE=1 SV=2 [Swiss-Prot] Ensembl_locations(Chr-bp):12-51839040 Hepatocyte nuclear factor 3-alpha [hmr_yeast5_DM3-1_pombe.fasta] Hepatocyte nuclear factor 3-alpha [ipi.MOUSE.v3.06.fasta] Hepatocyte nuclear factor 3-alpha (HNF-3A) (Forkhead box protein A1) [nrdb_11152004_Chlamydomonas] Tax_Id=10090 Hepatocyte nuclear factor 3-alpha [EBI-IPI_mouse_3.17_05-10-2006_con_reversed.fasta] forkhead box A1 [Mus musculus] [mouse-NCBI-010306_contam_rand.fasta] PREDICTED: similar to Hepatocyte nuclear factor 3-alpha (HNF-3A) (Forkhead box protein A1) [Mus musculus] [mouse-NCBI-010306_contam_rand.fasta] Hepatocyte nuclear factor 3-alpha (HNF-3-alpha) (HNF-3A) (Forkhead box protein A1) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Forkhead box A1 [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10090 HEPATOCYTE NUCLEAR FACTOR 3-ALPHA [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10090 Gene_Symbol=LOC100047556;Foxa1 Hepatocyte nuclear factor 3-alpha [mouse-ipi-250309-contam.fasta] Tax_Id=10090 Gene_Symbol=Foxa1 Hepatocyte nuclear factor 3-alpha [zeeyong.fasta] Tax_Id=10090 Gene_Symbol=Foxa1;LOC100047556 Hepatocyte nuclear factor 3-alpha ENSMUSG00000035451 IPI00310116 [IPIxENS.MOUSE_plus_REVERSE.fasta] hepatocyte nuclear factor 3-alpha [Mus musculus] [NCBI-RefSeq_mouse_na_05-17-2010_reversed.fasta] IPI:IPI00310116.1\|SWISS-PROT:P35582\|TREMBL:Q4VA63;Q61583\|ENSEMBL:ENSMUSP00000041118\|REFSEQ:NP_032285;XP_001478326 Tax_Id=10090 Gene_Symbol=Foxa1;LOC100047556 Hepatocyte nuclear factor 3-alpha [ipi.MOUSE.fasta.20090209] Tax_Id=10090 Gene_Symbol=Foxa1;LOC100047556 Hepatocyte nuclear factor 3-alpha [EBI-IPI_mouse_01-01-2009_reversed.fasta] Hepatocyte nuclear factor 3-alpha OS=Mus musculus GN=Foxa1 [011711_HMR.fasta] sp\|P35582\|FOXA1_MOUSE Hepatocyte nuclear factor 3-alpha OS=Mus musculus GN=Foxa1 PE=1 SV=2 [uniprot.sptr.mouse.20130102]
Organism:	Mus musculus
Length:	468 amino acids
Gene Ontology:
Cellular Component:	nucleus [UNKNOWN][IDA]
Biological Process:	chromatin modification [IEA] branching involved in lung morphogenesis [IGI] prostate gland epithelium morphogenesis [IMP] lung epithelial cell differentiation [IGI] transcription [IEA] multicellular organismal development [IEA] regulation of transcription, DNA-dependent [IEA] positive regulation of neuron differentiation [IGI][IMP] secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development [IMP] regulation of transcription [IEA] positive regulation of transcription from RNA polymerase II promoter [UNKNOWN][IDA][IGI] prostate gland stromal morphogenesis [IMP] hormone metabolic process [IMP] epithelial cell maturation involved in prostate gland development [IMP] negative regulation of transcription from RNA polymerase II promoter [UNKNOWN][IMP] epithelial-mesenchymal signaling involved in prostate gland development [IGI] neuron fate specification [IGI] glucose homeostasis [IMP] tube morphogenesis [IMP] regulation of gene expression [IGI] lung development [IGI]
Molecular Function:	DNA binding [IDA] protein domain specific binding [UNKNOWN] transcription factor activity [UNKNOWN][IDA] double-stranded DNA binding [UNKNOWN] sequence-specific DNA binding [UNKNOWN][IDA] transcription activator activity [UNKNOWN] transcription factor binding [UNKNOWN]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLGTVKMEGH ESNDWNSYYA DTQEAYSSVP VSNMNSGLGS MNSMNTYMTM NTMTTSGNMT  60
   61 PASFNMSYAN TGLGAGLSPG AVAGMPGASA GAMNSMTAAG VTAMGTALSP GGMGSMGAQP 120
  121 ATSMNGLGPY AAAMNPCMSP MAYAPSNLGR SRAGGGGDAK TFKRSYPHAK PPYSYISLIT 180
  181 MAIQQAPSKM LTLSEIYQWI MDLFPYYRQN QQRWQNSIRH SLSFNDCFVK VARSPDKPGK 240
  241 GSYWTLHPDS GNMFENGCYL RRQKRFKCEK QPGAGGGSGG GGSKGGPESR KDPSGPGNPS 300
  301 AESPLHRGVH GKASQLEGAP APGPAASPQT LDHSGATATG GASELKSPAS SSAPPISSGP 360
  361 GALASVPPSH PAHGLAPHES QLHLKGDPHY SFNHPFSINN LMSSSEQQHK LDFKAYEQAL 420
  421 QYSPYGATLP ASLPLGSASV ATRSPIEPSA LEPAYYQGVY SRPVLNTS

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: FOXA1_MOUSE

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: