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Protein Overview: PHS_MOUSE

General Information:
Name(s) found: PHS_MOUSE [Swiss-Prot]
Description(s) found:
Found 21 descriptions.
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  • Pterin-4-alpha-carbinolamine dehydratase OS=Mus musculus GN=Pcbd1 PE=1 SV=2 [Swiss-Prot]
    • Organism: Mus musculus
    Length: 104 amino acids

    Gene Ontology:
    Cellular Component: nucleus [UNKNOWN][IPI]
    cytoplasm [IEA]
    Biological Process: protein homotetramerization [IPI]
    transcription [IEA]
    tetrahydrobiopterin biosynthetic process [IEA]
    positive regulation of transcription [UNKNOWN]
    regulation of protein homodimerization activity [UNKNOWN]
    protein heterooligomerization [IPI]
    regulation of transcription [IEA]
    Molecular Function: protein binding [IPI]
    transcription coactivator activity [UNKNOWN]
    phenylalanine 4-monooxygenase activity [IDA]
    lyase activity [IEA]
    4-alpha-hydroxytetrahydrobiopterin dehydratase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAGKAHRLSA EERDQLLPNL RAVGWNEVEG RDAIFKQFHF KDFNRAFGFM TRVALQAEKL  60
   61 DHHPEWFNVY NKVHITLSTH ECAGLSERDI NLASFIEQVA VSMT

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..104] PSI-BLAST 38.045757 Pterin-4a-carbinolamine dehydratase (PCD)/dimerization cofactor of HNF1 (DCoH)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • 4-alpha-hydroxytetrahydrobiopterin dehydratase activity
    		•  6.27157822952381 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.43253022834875 bayes_pls_golite062009
  • phenylalanine 4-monooxygenase activity
    		•  2.07153680701772 bayes_pls_golite062009
  • binding
    		•  1.91757396487631 bayes_pls_golite062009
  • transcription activator activity
    		•  1.76965686339133 bayes_pls_golite062009
  • protein binding
    		•  1.5922433129317 bayes_pls_golite062009
  • catalytic activity
    		•  1.39967796334655 bayes_pls_golite062009
  • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen
    		•  1.1107181321593 bayes_pls_golite062009
  • carbon-oxygen lyase activity
    		•  0.738746392707103 bayes_pls_golite062009
  • hydro-lyase activity
    		•  0.699903508958642 bayes_pls_golite062009
  • lyase activity
    		•  0.685050647082958 bayes_pls_golite062009
  • transcription factor binding
    		•  0.303837517417996 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle