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Catalysis of the breakage of a carbon-oxygen bond. Catalysis of the cleavage of a carbon-oxygen bond by elimination of water. Catalysis of the reaction: (6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4-alpha-hydroxypterin = (6R)-6-(L-erythro-1,2-dihydroxypropyl)-7,8-dihydro-6H-pterin + H2O.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: 4-alpha-hydroxytetrahydrobiopterin dehydratase activity
Acc: GO:0008124
Aspect: Molecular Function
Desc: Catalysis of the reaction: (6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4-alpha-hydroxypterin = (6R)-6-(L-erythro-1,2-dihydroxypropyl)-7,8-dihydro-6H-pterin + H2O.
Synonyms:
  • pterin-4-alpha-carbinolamine dehydratase activity
  • pterin-4a-carbinolamine dehydratase activity
  • 4-alpha-hydroxy-tetrahydropterin dehydratase activity
  • tetrahydrobiopterin dehydratase activity
  • 4a-hydroxytetrahydrobiopterin dehydratase activity
  • (6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin hydro-lyase [(6R)-6-(L-erythro-1,2-dihydroxypropyl)-7,8-dihydro-6H-pterin-forming]
  • 4a-hydroxytetrahydrobiopterin hydro-lyase activity
  • 4alpha-hydroxy-tetrahydropterin dehydratase activity
  • pterin-4alpha-carbinolamine dehydratase activity
Proteins in PDR annotated with:
   This term: 14 [Search]
   Term or descendants: 14 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0008124 - 4-alpha-hydroxytetrahydrobiopterin dehydratase activity (interactive image map)
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