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Protein Overview: SNF4Agamma-PI

General Information:
Name(s) found: SNF4Agamma-PI / FBpp0110237 [FlyBase]
Description(s) found:
Found 17 descriptions.
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  • The gene SNF4/AMP-activated protein kinase gamma subunit is referred to in FlyBase by the symbol Dmel\SNF4AÃ?&#142;Ã?³ (CG17299, FBgn0025803). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:16966463..17038409. It has the cytological map location 93C1-93C5. Based on sequence similarity, it is predicted to have molecular function</span>: AMP-activated protein kinase activity. There is experimental evidence that it is involved in the biological process</span>: positive regulation of cell cycle; cholesterol homeostasis. 51 alleles are reported. The phenotypes of these alleles are annotated with: adult central complex; trichogen cell; adult central nervous system; tormogen cell; adult brain. It has 16 annotated transcripts and 16 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 538 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: positive regulation of cell cycle [IGI]
    protein amino acid phosphorylation [ISS]
    cholesterol homeostasis [IMP]
    Molecular Function: AMP-activated protein kinase activity [ISS][NAS]
    protein serine/threonine kinase activity [NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLQLHFYSNH AGRLVLGGGN RRPTDVLCYP LESIKEFEQI SEAWKRLLAE LLKKEEDDSQ  60
   61 IFVKFFRFHK CYDLIPTSAK LVVFDTQLLV KKAFYALVYN GVRAAPLWDS EKQQFVGMLT 120
  121 ITDFIKILQM YYKSPNASME QLEEHKLDTW RSVLHNQVMP LVSIGPDASL YDAIKILIHS 180
  181 RIHRLPVIDP ATGNVLYILT HKRILRFLFL YINELPKPAY MQKSLRELKI GTYNNIETAD 240
  241 ETTSIITALK KFVERRVSAL PLVDSDGRLV DIYAKFDVIN LAAEKTYNDL DVSLRKANEH 300
  301 RNEWFEGVQK CNLDESLYTI MERIVRAEVH RLVVVDENRK VIGIISLSDI LLYLVLRPSG 360
  361 EGVGGSESSL RASDPVLLRK VAEVEIPATA AAATTTTPPR SPSAGSGNRS LIEDIPEEET 420
  421 APARSDDADS DNNKSASEDK ANNNQHDQTT TAATANGDSN NSPVEVSFAD EAQEEEAADQ 480
  481 VERSNCDDDD QPALAEIERK NASMDDDEDD GMSSAVSAAS ALGQSLTPAA QEMALVSE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..136] PSI-BLAST 44.09691 No description for 2v8qE was found.
    2 View Details [137..224] FFAS03 2.62 No description for 2uv6A was found.
    3 View Details [225..346] PSI-BLAST 16.69897 No description for 2uv4A was found.
    4 View Details [347..538] PSI-BLAST 15.0 Inosine monophosphate dehydrogenase (IMPDH)


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle