YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: Imp-PI

General Information:
Name(s) found: Imp-PI / FBpp0110267 [FlyBase]
Description(s) found:
Found 9 descriptions.
SHOW ALL
  • The gene IGF-II mRNA-binding protein is referred to in FlyBase by the symbol Dmel\Imp (CG1691, FBgn0030235). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:10690030..10716815. It has the cytological map location 9F2-9F4. Based on sequence similarity, it is predicted to have molecular function</span>: mRNA binding. There is experimental evidence that it is involved in the biological process</span>: nervous system development; spermatogenesis. 51 alleles are reported. The phenotypes of these alleles are annotated with: chorion; egg; macrochaeta. It has 10 annotated transcripts and 10 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 588 amino acids

    Gene Ontology:
    Cellular Component: catalytic step 2 spliceosome [IDA]
    precatalytic spliceosome [IDA]
    Biological Process: synaptic growth at neuromuscular junction [IMP]
    spermatogenesis [IEP]
    nervous system development [IMP]
    nuclear mRNA splicing, via spliceosome [IC]
    Molecular Function: mRNA binding [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQTRFEDIEP LLKPYGIVKQ CEAISSKDQN TQTVHITFEN PEQAQRAAVG LNGVEFEGSK  60
   61 LHAEQLDKNQ RRSQRNQRNP YPGMPGPGRQ ADFPLRILVQ SEMVGAIIGR QGSTIRTITQ 120
  121 QSRARVDVHR KENVGSLEKS ITIYGNPENC TNACKRILEV MQQEAISTNK GELSPECSEI 180
  181 CLKILAHNNL IGRIIGKSGN TIKRIMQDTD TKITVSSIND INSFNLERII TVKGLIENMS 240
  241 RAENQISTKL RQSYENDLQA MAPQSLMFPG LHPMAMMSTP GNGMVFNTSM PFPSCQSFAM 300
  301 SKTPASVVPP VFPNDLQETT YLYIPNNAVG AIIGTRGSHI RSIMRFSNAS LKIAPLDADK 360
  361 PLDQQTERKV TIVGTPEGQW KAQYMIFEKM REEGFMCGTD DVRLTVELLV ASSQVGRIIG 420
  421 KGGQNVRELQ RVTGSVIKLP EHALAPPSGG DEETPVHIIG LFYSVQSAQR RIRAMMLSTN 480
  481 PPPITKKQKA AKEQLQQQQQ SLAGAASSGS QQQQPQSPSQ QQALPPQLHH QPVSSASSSS 540
  541 TPPAHHQQQA STAATSHQLQ QQQPSPPPPG NATAAAAQQQ QQLASSQQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..588] PSI-BLAST 47.0 Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3; Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domains 1 and 4; Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 6; Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domains 2 and 5

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • transcription regulator activity
    		•  3.24341202600661 bayes_pls_golite062009
  • RNA binding
    		•  2.47373172667773 bayes_pls_golite062009
  • 3'-5'-exoribonuclease activity
    		•  1.75348883519008 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.64421905267791 bayes_pls_golite062009
  • binding
    		•  1.38311294671926 bayes_pls_golite062009
  • transcription termination factor activity
    		•  1.01993495617192 bayes_pls_golite062009
  • DNA binding
    		•  1.01454217691792 bayes_pls_golite062009
  • ribonuclease activity
    		•  0.825588323751637 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  0.487005194393476 bayes_pls_golite062009
  • mRNA binding
    		•  0.403794675006504 bayes_pls_golite062009
    		• 0.371217633915521 bayes_pls_golite062009
  • transcription factor activity
    		•  0.298729064067577 bayes_pls_golite062009
  • exoribonuclease activity, producing 5'-phosphomonoesters
    		•  0.21915720954962 bayes_pls_golite062009
  • structural molecule activity
    		•  0.210607270192918 bayes_pls_golite062009
  • exoribonuclease activity
    		•  0.20391251413344 bayes_pls_golite062009
  • catalytic activity
    		•  0.10089766806364 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.0287026367466632 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle