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View Structure Prediction Details

Protein: Imp-PI
Organism: Drosophila melanogaster
Length: 588 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Imp-PI.

Description E-value Query
Range
Subject
Range
gi|73976018 - gi|73976018|ref|XP_863310.1| PREDICTED: similar to IGF-II mRNA-binding protein 3 isoform 5 [Canis fa...
331.0 [0..2] [496..91]

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Predicted Domain #1
Region A:
Residues: [1-588]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQTRFEDIEP LLKPYGIVKQ CEAISSKDQN TQTVHITFEN PEQAQRAAVG LNGVEFEGSK  60
   61 LHAEQLDKNQ RRSQRNQRNP YPGMPGPGRQ ADFPLRILVQ SEMVGAIIGR QGSTIRTITQ 120
  121 QSRARVDVHR KENVGSLEKS ITIYGNPENC TNACKRILEV MQQEAISTNK GELSPECSEI 180
  181 CLKILAHNNL IGRIIGKSGN TIKRIMQDTD TKITVSSIND INSFNLERII TVKGLIENMS 240
  241 RAENQISTKL RQSYENDLQA MAPQSLMFPG LHPMAMMSTP GNGMVFNTSM PFPSCQSFAM 300
  301 SKTPASVVPP VFPNDLQETT YLYIPNNAVG AIIGTRGSHI RSIMRFSNAS LKIAPLDADK 360
  361 PLDQQTERKV TIVGTPEGQW KAQYMIFEKM REEGFMCGTD DVRLTVELLV ASSQVGRIIG 420
  421 KGGQNVRELQ RVTGSVIKLP EHALAPPSGG DEETPVHIIG LFYSVQSAQR RIRAMMLSTN 480
  481 PPPITKKQKA AKEQLQQQQQ SLAGAASSGS QQQQPQSPSQ QQALPPQLHH QPVSSASSSS 540
  541 TPPAHHQQQA STAATSHQLQ QQQPSPPPPG NATAAAAQQQ QQLASSQQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 47.0
Match: 1e3hA
Description: Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3; Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domains 1 and 4; Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 6; Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domains 2 and 5
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 3.24341202600661 bayes_pls_golite062009
RNA binding 2.47373172667773 bayes_pls_golite062009
3'-5'-exoribonuclease activity 1.75348883519008 bayes_pls_golite062009
nucleic acid binding 1.64421905267791 bayes_pls_golite062009
binding 1.38311294671926 bayes_pls_golite062009
transcription termination factor activity 1.01993495617192 bayes_pls_golite062009
DNA binding 1.01454217691792 bayes_pls_golite062009
ribonuclease activity 0.825588323751637 bayes_pls_golite062009
structural constituent of ribosome 0.487005194393476 bayes_pls_golite062009
mRNA binding 0.403794675006504 bayes_pls_golite062009
0.371217633915521 bayes_pls_golite062009
transcription factor activity 0.298729064067577 bayes_pls_golite062009
exoribonuclease activity, producing 5'-phosphomonoesters 0.21915720954962 bayes_pls_golite062009
structural molecule activity 0.210607270192918 bayes_pls_golite062009
exoribonuclease activity 0.20391251413344 bayes_pls_golite062009
catalytic activity 0.10089766806364 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.0287026367466632 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle