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Protein Overview: FABP4_MOUSE

General Information:
Name(s) found: FABP4_MOUSE [Swiss-Prot]
Description(s) found:
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  • gi|71060107|emb|CAJ18597.1| Fabp4 [Mus musculus] [NCBI NR]
  • gi|32484344|gb|AAH54426.1| Fatty acid binding protein 4, adipocyte [Mus musculus] [NCBI NR]
  • gi|293695|gb|AAA39416.1| lipid-binding protein [NCBI NR]
  • gi|26353560|dbj|BAC40410.1| unnamed protein product [Mus musculus] [NCBI NR]
  • gi|148673224|gb|EDL05171.1| fatty acid binding protein 4, adipocyte [Mus musculus] [NCBI NR]
  • gi|14149635|ref|NP_077717.1| fatty acid binding protein 4, adipocyte [Mus musculus] [NCBI NR]
  • gi|12833626|dbj|BAB22601.1| unnamed protein product [Mus musculus] [NCBI NR]
  • gi|119782|sp|P04117.3|FABP4_MOUSE RecName: Full=Fatty acid-binding protein, adipocyte; AltName: Full=A-FABP; Short=AFABP; AltName: Full=Fatty acid-binding protein 4; AltName: Full=Adipocyte lipid-binding protein; Short=ALBP; AltName: Full=P2 adipocyte pro [NCBI NR]
  • Fatty acid-binding protein, adipocyte - Mus musculus (Mouse) [Swiss-Prot]
  • Fatty acid-binding protein, adipocyte OS=Mus musculus GN=Fabp4 PE=1 SV=3 [Swiss-Prot]
  • Ensembl_locations(Chr-bp):3-10239795 fatty acid binding protein 4, adipocyte [hmr_yeast5_DM3-1_pombe.fasta]
  • fatty acid binding protein 4, adipocyte; adipocyte protein aP2; lipid binding protein-like [HMR_022704-rand.fasta]
  • fatty acid binding protein 4, adipocyte [Mus musculus]gi|32484344|gb|AAH54426.1| Fatty acid binding protein 4, adipocyte [Mus musculus]gi|26353560|dbj|BAC40410.1| unnamed protein product [Mus musculus]gi|119782|sp|P04117|FABA_MOUSE Fatty acid-binding p [nrdb_11152004_Chlamydomonas]
  • (NM_024406) fatty acid binding protein 4, adipocyte; adipocyte protein aP2; lipid binding protein-like [Mus musculus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • fatty acid binding protein 4, adipocyte [Mus musculus] [mouse-NCBI-010306_contam_rand.fasta]
  • Fatty acid-binding protein, adipocyte (A-FABP) (AFABP) (Fatty acid-binding protein 4) (Adipocyte lipid-binding protein) (ALBP) (P2 adipocyte protein) (Myelin P2 protein homolog) (3T3-L1 lipid-binding protein) (Protein 422) (P15) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • unnamed protein product [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Fatty acid binding protein 4, adipocyte [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Fabp4 [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • lipid-binding protein [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Tax_Id=10090 FATTY ACID BINDING PROTEIN 4, ADIPOCYTE [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • Tax_Id=10090 Gene_Symbol=Fabp4 Fatty acid-binding protein, adipocyte [mouse-ipi-250309-contam.fasta]
  • Fatty acid-binding protein, adipocyte (AFABP) (Adipocyte lipid-binding protein) (ALBP) (A-FABP) (P2 adipocyte protein) (Myelin P2 protein homolog) (3T3-L1 lipid-binding protein) (422 protein) (P15) [nr-271106-contam.fasta]
  • Tax_Id=10090 Gene_Symbol=Fabp4 Fatty acid-binding protein, adipocyte ENSMUSG00000062515 IPI00116705 IPI00473910 [IPIxENS.MOUSE_plus_REVERSE.fasta]
  • fatty acid-binding protein, adipocyte [Mus musculus] [NCBI-RefSeq_mouse_na_05-17-2010_reversed.fasta]
  • IPI:IPI00116705.5|SWISS-PROT:P04117|TREMBL:Q542H7|ENSEMBL:ENSMUSP00000029041|REFSEQ:NP_077717 Tax_Id=10090 Gene_Symbol=Fabp4 Fatty acid-binding protein, adipocyte [ipi.MOUSE.fasta.20090209]
  • Fatty acid-binding protein, adipocyte OS=Mus musculus GN=Fabp4 [011711_HMR.fasta]
  • sp|P04117|FABP4_MOUSE Fatty acid-binding protein, adipocyte OS=Mus musculus GN=Fabp4 PE=1 SV=3 [uniprot.sptr.mouse.20130102]
  • tr|Q542H7|Q542H7_MOUSE Fabp4 protein OS=Mus musculus GN=Fabp4 PE=2 SV=1 [uniprot.sptr.mouse.20130102]
  • Fabp4 protein OS=Mus musculus GN=Fabp4 PE=2 SV=1 [mouse-uniprot-290313-contam.fasta]
  • Isoform of P04117, Fabp4 protein OS=Mus musculus GN=Fabp4 PE=1 SV=1 [MOUSE.fasta.20160308]
    • Organism: Mus musculus
    Length: 132 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IEA]
    cytoplasm [IEA]
    cytosol [UNKNOWN]
    Biological Process: white fat cell differentiation [IDA]
    brown fat cell differentiation [IDA]
    negative regulation of transcription [IMP]
    positive regulation of inflammatory response [IMP]
    positive regulation of cell proliferation [UNKNOWN]
    cytokine production [IMP]
    negative regulation of protein kinase activity [IMP]
    cholesterol homeostasis [IMP]
    transport [IEA]
    fatty acid metabolic process [UNKNOWN]
    Molecular Function: lipid binding [IEA]
    transcription repressor activity [IMP]
    binding [IEA]
    transporter activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MCDAFVGTWK LVSSENFDDY MKEVGVGFAT RKVAGMAKPN MIISVNGDLV TIRSESTFKN  60
   61 TEISFKLGVE FDEITADDRK VKSIITLDGG ALVQVQKWDG KSTTIKRKRD GDKLVVECVM 120
  121 KGVTSTRVYE RA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..132] PSI-BLAST 45.522879 No description for 2qm9A was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • long-chain fatty acid transporter activity
    		•  5.31242454679135 bayes_pls_golite062009
  • fatty acid transporter activity
    		•  5.05947161650978 bayes_pls_golite062009
  • lipid transporter activity
    		•  4.30505384117861 bayes_pls_golite062009
  • retinoid binding
    		•  3.86745158299736 bayes_pls_golite062009
  • isoprenoid binding
    		•  3.80802424204178 bayes_pls_golite062009
  • lysophospholipid transporter activity
    		•  3.53484598441971 bayes_pls_golite062009
  • retinol binding
    		•  3.41359399354212 bayes_pls_golite062009
  • binding
    		•  2.93830472620404 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.27413749831465 bayes_pls_golite062009
  • transporter activity
    		•  2.15627660314839 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.45696778890481 bayes_pls_golite062009
  • protein binding
    		•  1.23450129884619 bayes_pls_golite062009
  • prostaglandin-D synthase activity
    		•  1.18764036773412 bayes_pls_golite062009
  • lipid binding
    		•  1.0002255159651 bayes_pls_golite062009
  • retinol transporter activity
    		•  0.811095267558536 bayes_pls_golite062009
  • fatty acid binding
    		•  0.761923641769607 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.670647472301401 bayes_pls_golite062009
  • retinoic acid binding
    		•  0.539496110498594 bayes_pls_golite062009
  • intramolecular oxidoreductase activity
    		•  0.50851501669551 bayes_pls_golite062009
  • bile acid binding
    		•  0.37501307074598 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle