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Protein Overview: CD8B_MOUSE

General Information:
Name(s) found: CD8B_MOUSE [Swiss-Prot]
Description(s) found:
Found 35 descriptions.
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  • T-cell surface glycoprotein CD8 beta chain OS=Mus musculus GN=Cd8b PE=1 SV=1 [Swiss-Prot]
    • Organism: Mus musculus
    Length: 213 amino acids

    Gene Ontology:
    Cellular Component: membrane [IEA]
    integral to membrane [IEA]
    external side of plasma membrane [IDA]
    cell surface [IDA]
    Biological Process: NONE FOUND
    Molecular Function: protein binding [IPI]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQPWLWLVFS MKLAALWSSS ALIQTPSSLL VQTNHTAKMS CEVKSISKLT SIYWLRERQD  60
   61 PKDKYFEFLA SWSSSKGVLY GESVDKKRNI ILESSDSRRP FLSIMNVKPE DSDFYFCATV 120
  121 GSPKMVFGTG TKLTVVDVLP TTAPTKKTTL KMKKKKQCPF PHPETQKGLT CSLTTLSLLV 180
  181 VCILLLLAFL GVAVYFYCVR RRARIHFMKQ FHK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..141] PSI-BLAST 16.30103 Crystal structure of a CD8ab heterodimer
    2 View Details [142..213] PSI-BLAST 9.154902 No description for 2h3nB was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • antigen binding
    		•  5.9176308851452 bayes_pls_golite062009
  • receptor activity
    		•  4.00123250685257 bayes_pls_golite062009
  • transmembrane receptor activity
    		•  3.81769911097805 bayes_pls_golite062009
  • peptide antigen binding
    		•  3.64034637674979 bayes_pls_golite062009
  • molecular transducer activity
    		•  3.10913345555941 bayes_pls_golite062009
  • signal transducer activity
    		•  3.10913345555941 bayes_pls_golite062009
  • binding
    		•  2.74708244886154 bayes_pls_golite062009
  • growth factor binding
    		•  2.28613301180608 bayes_pls_golite062009
  • T cell receptor binding
    		•  2.12089279430732 bayes_pls_golite062009
  • fibroblast growth factor 1 binding
    		•  2.0791723060792 bayes_pls_golite062009
  • fibroblast growth factor binding
    		•  1.66833360192732 bayes_pls_golite062009
  • IgG binding
    		•  1.6222936767122 bayes_pls_golite062009
  • transmembrane receptor protein tyrosine kinase activity
    		•  1.52958974617075 bayes_pls_golite062009
  • transmembrane receptor protein kinase activity
    		•  1.30657787244536 bayes_pls_golite062009
  • fibroblast growth factor receptor activity
    		•  1.24730237107473 bayes_pls_golite062009
  • protein binding
    		•  1.17809977833322 bayes_pls_golite062009
  • immunoglobulin receptor activity
    		•  1.06402558628866 bayes_pls_golite062009
  • G-protein coupled receptor activity
    		•  1.02428106476324 bayes_pls_golite062009
  • receptor binding
    		•  0.909733688848793 bayes_pls_golite062009
  • protein tyrosine kinase activity
    		•  0.904613290855333 bayes_pls_golite062009
  • immunoglobulin binding
    		•  0.84834833214265 bayes_pls_golite062009
  • protein complex binding
    		•  0.83543827718565 bayes_pls_golite062009
  • peptide binding
    		•  0.729048089532569 bayes_pls_golite062009
  • coreceptor activity
    		•  0.661209696849389 bayes_pls_golite062009
  • cytokine binding
    		•  0.631436442105379 bayes_pls_golite062009
  • cytokine receptor activity
    		•  0.34165331857492 bayes_pls_golite062009
  • MHC class II receptor activity
    		•  0.251167772391909 bayes_pls_golite062009
  • olfactory receptor activity
    		•  0.20101044847022 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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