Protein Overview: PPARG_MOUSE

General Information:
Name(s) found:	PPARG_MOUSE [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|6755138\|ref\|NP_035276.1\| peroxisome proliferator activated receptor gamma [Mus musculus] [NCBI NR] pir\|\|A54101 peroxisome proliferator-activated receptor gamma - mouse [NCBI NR] gi\|500640\|gb\|AAA62277.1\| peroxisome proliferator activated protein-gamma-2 [NCBI NR] gi\|13432235\|sp\|P37238.3\|PPARG_MOUSE RecName: Full=Peroxisome proliferator-activated receptor gamma; Short=PPAR-gamma; AltName: Full=Nuclear receptor subfamily 1 group C member 3 [NCBI NR] (P37238) Peroxisome proliferator activated receptor gamma (PPAR-gamma) [Swiss-Prot] Peroxisome proliferator-activated receptor gamma OS=Mus musculus GN=Pparg PE=1 SV=3 [Swiss-Prot] Ensembl_locations(Chr-bp):6-116038584;6-116038584 Splice isoform 2 of P37238 Peroxisome proliferator activated receptor gamma [hmr_yeast5_DM3-1_pombe.fasta] peroxisome proliferator activated receptor gamma; peroxisome proliferator activator receptor gamma; peroxisome proliferator activator receptor gamma 2 [HMR_022704-rand.fasta] peroxisome proliferator activated receptor gamma; peroxisome proliferator activator receptor gamma 2; peroxisome proliferator activator receptor gamma [071204_hmrz_cont.fasta] Splice Isoform 2 of Peroxisome proliferator activated receptor gamma [ipi.MOUSE.v3.06.fasta] peroxisome proliferator activated receptor gamma [Mus musculus]gi\|627929\|pir\|\|A54101 peroxisome proliferator-activated receptor gamma - mousegi\|13432235\|sp\|P37238\|PPAT_MOUSE Peroxisome proliferator activated receptor gamma (PPAR-gamma)gi\|500640\|gb\|AAA6 [nrdb_11152004_Chlamydomonas] Tax_Id=10090 Splice Isoform 2 of Peroxisome proliferator-activated receptor gamma [EBI-IPI_mouse_3.17_05-10-2006_con_reversed.fasta] (NM_011146) peroxisome proliferator activated receptor gamma; peroxisome proliferator activator receptor gamma [Mus musculus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] peroxisome proliferator activated receptor gamma [Mus musculus] [mouse-NCBI-010306_contam_rand.fasta] Tax_Id=10090 Splice Isoform 2 of Peroxisome proliferator activated receptor gamma [EBI-IPI_mouse_3.06_05-10-2005_origrev_con.fasta] Peroxisome proliferator-activated receptor gamma (PPAR-gamma) (Nuclear receptor subfamily 1 group C member 3) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] peroxisome proliferator activated protein-gamma-2 [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10090 SPLICE ISOFORM 1 OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10090 Gene_Symbol=Pparg Isoform 2 of Peroxisome proliferator-activated receptor gamma [mouse-ipi-250309-contam.fasta] Peroxisome proliferator-activated receptor gamma (PPAR-gamma) [nr-271106-contam.fasta] Tax_Id=10090 Gene_Symbol=Pparg Isoform 2 of Peroxisome proliferator-activated receptor gamma ENSMUSG00000000440 IPI00125193 IPI00266075 [IPIxENS.MOUSE_plus_REVERSE.fasta] IPI:IPI00125193.1\|SWISS-PROT:P37238-1 Tax_Id=10090 Gene_Symbol=Pparg Isoform 2 of Peroxisome proliferator-activated receptor gamma [ipi.MOUSE.fasta.20090209] Isoform 2 of Peroxisome proliferator-activated receptor gamma OS=Mus musculus GN=Pparg [011711_HMR.fasta] sp\|P37238\|PPARG_MOUSE Peroxisome proliferator-activated receptor gamma OS=Mus musculus GN=Pparg PE=1 SV=3 [uniprot.sptr.mouse.20130102]
Organism:	Mus musculus
Length:	505 amino acids
Gene Ontology:
Cellular Component:	nucleus [UNKNOWN][IDA] transcriptional repressor complex [IC] cytosol [UNKNOWN][IDA]
Biological Process:	negative regulation of cell proliferation [UNKNOWN][IMP] positive regulation of fat cell differentiation [IEP][IMP] positive regulation of transcription [IDA] fat cell differentiation [IDA][IGI] placenta development [IMP] regulation of transcription [IDA] positive regulation of transcription from RNA polymerase II promoter [IDA] positive regulation of oligodendrocyte differentiation [UNKNOWN] white fat cell differentiation [IDA][IEP] negative regulation of transcription from RNA polymerase II promoter [IDA] brown fat cell differentiation [IDA] inflammatory response [TAS] long-chain fatty acid transport [IMP] negative regulation of transcription, DNA-dependent [IMP] positive regulation of fatty acid oxidation [UNKNOWN] negative regulation of cell growth [UNKNOWN] response to lipid [IDA] positive regulation of gene-specific transcription from RNA polymerase II promoter [IDA] negative regulation of gene-specific transcription from RNA polymerase II promoter [IDA] transcription [IEA] regulation of transcription, DNA-dependent [IEA] regulation of fat cell differentiation [UNKNOWN][IDA][IGI] negative regulation of acute inflammatory response [UNKNOWN] epithelial cell differentiation [IGI] fatty acid oxidation [UNKNOWN] cell fate commitment [IGI] negative regulation of cytokine production [IMP] regulation of lipid metabolic process [UNKNOWN] negative regulation of telomerase activity [UNKNOWN]
Molecular Function:	zinc ion binding [IEA] sequence-specific DNA binding [IEA] chromatin binding [IDA] receptor activity [IEA] DNA binding [UNKNOWN][IDA][IPI] transcription factor activity [IDA] protein binding [IPI] metal ion binding [IEA] ligand-dependent nuclear receptor activity [TAS] steroid hormone receptor activity [IEA] promoter binding [IDA] transcription activator activity [IDA] transcription repressor activity [IDA][IMP] arachidonic acid binding [IDA] specific transcriptional repressor activity [IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGETLGDSPV DPEHGAFADA LPMSTSQEIT MVDTEMPFWP TNFGISSVDL SVMEDHSHSF  60
   61 DIKPFTTVDF SSISAPHYED IPFTRADPMV ADYKYDLKLQ EYQSAIKVEP ASPPYYSEKT 120
  121 QLYNRPHEEP SNSLMAIECR VCGDKASGFH YGVHACEGCK GFFRRTIRLK LIYDRCDLNC 180
  181 RIHKKSRNKC QYCRFQKCLA VGMSHNAIRF GRMPQAEKEK LLAEISSDID QLNPESADLR 240
  241 ALAKHLYDSY IKSFPLTKAK ARAILTGKTT DKSPFVIYDM NSLMMGEDKI KFKHITPLQE 300
  301 QSKEVAIRIF QGCQFRSVEA VQEITEYAKN IPGFINLDLN DQVTLLKYGV HEIIYTMLAS 360
  361 LMNKDGVLIS EGQGFMTREF LKNLRKPFGD FMEPKFEFAV KFNALELDDS DLAIFIAVII 420
  421 LSGDRPGLLN VKPIEDIQDN LLQALELQLK LNHPESSQLF AKVLQKMTDL RQIVTEHVQL 480
  481 LHVIKKTETD MSLHPLLQEI YKDLY

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: PPARG_MOUSE

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: