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Protein Overview: gi|18450371, gi|...

General Information:
Name(s) found: gi|35786 [NCBI NR]
gi|33096774 [NCBI NR]
gi|20073057 [NCBI NR]
gi|18450371 [NCBI NR]
gi|18450369 [NCBI NR]
gi|158261489 [NCBI NR]
gi|119630968 [NCBI NR]
gi|119630967 [NCBI NR]
gi|10432439 [NCBI NR]
Description(s) found:
SHOW ONLY BEST
  • gi|35786|emb|CAA38065.1| protein-tyrosine phosphatase [Homo sapiens] [NCBI NR]
  • gi|33096774|emb|CAE11878.1| hypothetical protein [Homo sapiens] [NCBI NR]
  • gi|20073057|gb|AAH27308.1| Protein tyrosine phosphatase, receptor type, A [Homo sapiens] [NCBI NR]
  • gi|18450371|ref|NP_543031.1| protein tyrosine phosphatase, receptor type, A isoform 2 precursor [Homo sapiens] [NCBI NR]
  • gi|18450369|ref|NP_543030.1| protein tyrosine phosphatase, receptor type, A isoform 2 precursor [Homo sapiens] [NCBI NR]
  • gi|158261489|dbj|BAF82922.1| unnamed protein product [Homo sapiens] [NCBI NR]
  • gi|119630968|gb|EAX10563.1| hCG2020289, isoform CRA_b [Homo sapiens] [NCBI NR]
  • gi|119630967|gb|EAX10562.1| hCG2020289, isoform CRA_b [Homo sapiens] [NCBI NR]
  • gi|10432439|emb|CAC10337.1| protein tyrosine phosphatase, receptor type, A [Homo sapiens] [NCBI NR]
  • protein tyrosine phosphatase, receptor type, A isoform 2 precursor [hmr_yeast5_DM3-1_pombe.fasta]
  • protein tyrosine phosphatase, receptor type, A isoform 2 precursor; protein tyrosine phosphatase, receptor type, alpha polypeptide; PTPase-alpha; Leukocyte common antigen-related peptide (protein tyrosine phosphate); tyrosine phosphatase alpha; PTPLCA-rel [HMR_022704.fasta]
  • protein tyrosine phosphatase, receptor type, A isoform 2 precursor [Homo sapiens]gi|18450369|ref|NP_543030.1| protein tyrosine phosphatase, receptor type, A isoform 2 precursor [Homo sapiens]gi|20073057|gb|AAH27308.1| Protein tyrosine phosphatase, recep [nrdb_11152004_Chlamydomonas]
  • Tax_Id=9606 Splice Isoform 4 of Receptor-type tyrosine-protein phosphatase alpha precursor [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta]
  • (NM_080840) protein tyrosine phosphatase, receptor type, A, isoform 2 precursor; protein tyrosine phosphatase, receptor type, alpha polypeptide; PTPase-alpha; Leukocyte common antigen-related peptide (protein tyrosine phosphate); tyrosine phosphatase alph [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • (NM_080841) protein tyrosine phosphatase, receptor type, A, isoform 2 precursor; protein tyrosine phosphatase, receptor type, alpha polypeptide; PTPase-alpha; Leukocyte common antigen-related peptide (protein tyrosine phosphate); tyrosine phosphatase alph [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • protein tyrosine phosphatase, receptor type, A isoform 2 precursor [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta]
  • protein tyrosine phosphatase, receptor type, A [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • unnamed protein product [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Protein tyrosine phosphatase, receptor type, A [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • hCG2020289, isoform CRA_b [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • hypothetical protein [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • protein-tyrosine phosphatase [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Tax_Id=9606 Isoform 4 of Receptor-type tyrosine-protein phosphatase alpha precursor [EBI-IPI_human_3.23_11-02-2006_con_reversed.fasta]
  • Tax_Id=9606 SPLICE ISOFORM 4 OF PROTEIN-TYROSINE PHOSPHATASE ALPHA PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • Tax_Id=9606 Gene_Symbol=PTPRA Isoform 4 of Receptor-type tyrosine-protein phosphatase alpha [human-ipi-250309-contam.fasta]
  • IPI:IPI00304030.1|SWISS-PROT:P18433-4|TREMBL:A8K2G8;B7Z4F4;B7Z4Q5;Q59EV9|ENSEMBL:ENSP00000216877;ENSP00000314568;ENSP00000348468|REFSEQ:NP_543030;NP_543031|VEGA:OTTHUMP00000030063;OTTHUMP00000030064 Tax_Id=9606 Gene_Symbol=PTPRA Isoform 4 of Receptor-type [ipi.HUMAN.fasta.20090807]
  • [human_BMb_040710_contam.fasta]
  • Tax_Id=9606 Gene_Symbol=PTPRA Isoform 4 of Receptor-type tyrosine-protein phosphatase alpha precursor [EBI-IPI_human_3.30_06-28-2007_con_reversed.fasta]
  • Isoform 4 of Receptor-type tyrosine-protein phosphatase alpha OS=Homo sapiens GN=PTPRA [011711_HMR.fasta]
  • IPI:IPI00304030.1|SWISS-PROT:P18433-4|TREMBL:B7Z4F4;B7Z4Q5;D3DVX5;Q59EV9|ENSEMBL:ENSP00000216877;ENSP00000314568;ENSP00000348468|REFSEQ:NP_543030;NP_543031|VEGA:OTTHUMP00000030063;OTTHUMP00000030064 Tax_Id=9606 Gene_Symbol=PTPRA Isoform 4 of Receptor-type tyrosine-protein phosphatase alpha [ipi.HUMAN.fasta.20100406]
  • GeneSymbol=PTPRA Synonyms=HEPTP|HLPR|HPTPA|HPTPalpha|LRP|PTPA|PTPRL2|R-PTP-alpha|RPTPA receptor-type tyrosine-protein phosphatase alpha isoform 2 precursor [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta]
  • IPI:IPI00304030.1|SWISS-PROT:P18433-4|TREMBL:B7Z4Q5;Q59EV9|ENSEMBL:ENSP00000216877;ENSP00000314568;ENSP00000348468|REFSEQ:NP_543030;NP_543031|VEGA:OTTHUMP00000030063;OTTHUMP00000030064 Tax_Id=9606 Gene_Symbol=PTPRA Isoform 4 of Receptor-type tyrosine-protein phosphatase alpha [ipi.HUMAN.20110912.fasta]
  • Isoform 4 of Receptor-type tyrosine-protein phosphatase alpha GN=PTPRA [Doctor+uniprot-HUMAN-120911.fasta]
  • Isoform of P18433, Isoform 4 of Receptor-type tyrosine-protein phosphatase alpha OS=Homo sapiens GN=PTPRA [2016-04-human-contam-aPKC-His-Par6.fasta]
    • Organism: Homo sapiens
    Length: 793 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDSWFILVLL GSGLICVSAN NATTVAPSVG ITRLINSSTA EPVKEEAKTS NPTSSLTSLS  60
   61 VAPTFSPNIT LGPTYLTTVN SSDSDNGTTR TASTNSIGIT ISPNGTWLPD NQFTDARTEP 120
  121 WEGNSSTAAT TPETFPPSDE TPIIAVMVAL SSLLVIVFII IVLYMLRFKK YKQAGSHSNS 180
  181 FRLSNGRTED VEPQSVPLLA RSPSTNRKYP PLPVDKLEEE INRRMADDNK LFREEFNALP 240
  241 ACPIQATCEA ASKEENKEKN RYVNILPYDH SRVHLTPVEG VPDSDYINAS FINGYQEKNK 300
  301 FIAAQGPKEE TVNDFWRMIW EQNTATIVMV TNLKERKECK CAQYWPDQGC WTYGNIRVSV 360
  361 EDVTVLVDYT VRKFCIQQVG DMTNRKPQRL ITQFHFTSWP DFGVPFTPIG MLKFLKKVKA 420
  421 CNPQYAGAIV VHCSAGVGRT GTFVVIDAML DMMHTERKVD VYGFVSRIRA QRCQMVQTDM 480
  481 QYVFIYQALL EHYLYGDTEL EVTSLETHLQ KIYNKIPGTS NNGLEEEFKK LTSIKIQNDK 540
  541 MRTGNLPANM KKNRVLQIIP YEFNRVIIPV KRGEENTDYV NASFIDGYRQ KDSYIASQGP 600
  601 LLHTIEDFWR MIWEWKSCSI VMLTELEERG QEKCAQYWPS DGLVSYGDIT VELKKEEECE 660
  661 SYTVRDLLVT NTRENKSRQI RQFHFHGWPE VGIPSDGKGM ISIIAAVQKQ QQQSGNHPIT 720
  721 VHCSAGAGRT GTFCALSTVL ERVKAEGILD VFQTVKSLRL QRPHMVQTLE QYEFCYKVVQ 780
  781 EYIDAFSDYA NFK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..199] FFAS03 1.17 No description for 2j63A was found.
    2 View Details [200..512] PSI-BLAST 91.30103 Tyrosine phosphatase
    3 View Details [513..793] PSI-BLAST 82.69897 Crystal structure of the D2 domain of RPTPa

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • phosphoprotein phosphatase activity
    		•  7.30669036331612 bayes_pls_golite062009
  • phosphatase activity
    		•  7.03758345564381 bayes_pls_golite062009
  • phosphoric ester hydrolase activity
    		•  6.82821455971597 bayes_pls_golite062009
  • protein tyrosine phosphatase activity
    		•  6.07449851643404 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  5.83769298632658 bayes_pls_golite062009
  • receptor tyrosine kinase binding
    		•  5.39791540743613 bayes_pls_golite062009
  • transmembrane receptor protein phosphatase activity
    		•  4.57221148210263 bayes_pls_golite062009
  • transmembrane receptor protein tyrosine phosphatase activity
    		•  4.57221148210263 bayes_pls_golite062009
  • transmembrane receptor activity
    		•  3.4815731203374 bayes_pls_golite062009
  • receptor activity
    		•  3.2014960162856 bayes_pls_golite062009
  • hydrolase activity
    		•  2.90276529968189 bayes_pls_golite062009
  • protein tyrosine/serine/threonine phosphatase activity
    		•  2.77531895423367 bayes_pls_golite062009
  • insulin receptor binding
    		•  2.63442848340688 bayes_pls_golite062009
  • protein serine/threonine phosphatase activity
    		•  2.49496709551693 bayes_pls_golite062009
  • signal transducer activity
    		•  2.27602678801224 bayes_pls_golite062009
  • molecular transducer activity
    		•  2.27602678801224 bayes_pls_golite062009
  • protein binding
    		•  2.12487185456363 bayes_pls_golite062009
  • binding
    		•  2.06015698112379 bayes_pls_golite062009
  • non-membrane spanning protein tyrosine phosphatase activity
    		•  2.04600549829086 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  1.56455764981613 bayes_pls_golite062009
  • kinase activity
    		•  1.54798529194457 bayes_pls_golite062009
  • cell adhesion molecule binding
    		•  1.53727496158735 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.38282868576714 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  1.36326098454926 bayes_pls_golite062009
  • protein kinase activity
    		•  1.3466747511896 bayes_pls_golite062009
  • DNA binding
    		•  1.31084450519924 bayes_pls_golite062009
  • transporter activity
    		•  1.21792561830727 bayes_pls_golite062009
  • inositol or phosphatidylinositol phosphatase activity
    		•  1.1200449509328 bayes_pls_golite062009
  • catalytic activity
    		•  1.06283028154109 bayes_pls_golite062009
  • transferase activity
    		•  1.05480035577492 bayes_pls_golite062009
  • lipid phosphatase activity
    		•  1.05085928819585 bayes_pls_golite062009
  • beta-catenin binding
    		•  1.02079992407668 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  1.00030784939308 bayes_pls_golite062009
  • kinase binding
    		•  0.95875467592478 bayes_pls_golite062009
  • delta-catenin binding
    		•  0.89195134506409 bayes_pls_golite062009
  • protein kinase binding
    		•  0.83725631602383 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.73846553033987 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.49044345981587 bayes_pls_golite062009
  • phospholipase binding
    		•  0.43589778800599 bayes_pls_golite062009
  • insulin receptor substrate binding
    		•  0.366350463194201 bayes_pls_golite062009
  • phosphatidylinositol trisphosphate phosphatase activity
    		•  0.28805451968625 bayes_pls_golite062009
  • peptide hormone receptor binding
    		•  0.272080084933271 bayes_pls_golite062009
  • gated channel activity
    		•  0.217548650508289 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.200180223985633 bayes_pls_golite062009
  • enzyme binding
    		•  0.150910330021054 bayes_pls_golite062009
  • receptor binding
    		•  0.0137204844761347 bayes_pls_golite062009
    3
    Term Confidence Notes
  • phosphoprotein phosphatase activity
    		•  7.30669036331612 bayes_pls_golite062009
  • phosphatase activity
    		•  7.03758345564381 bayes_pls_golite062009
  • phosphoric ester hydrolase activity
    		•  6.82821455971597 bayes_pls_golite062009
  • protein tyrosine phosphatase activity
    		•  6.07449851643404 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  5.83769298632658 bayes_pls_golite062009
  • receptor tyrosine kinase binding
    		•  5.39791540743613 bayes_pls_golite062009
  • transmembrane receptor protein phosphatase activity
    		•  4.57221148210263 bayes_pls_golite062009
  • transmembrane receptor protein tyrosine phosphatase activity
    		•  4.57221148210263 bayes_pls_golite062009
  • transmembrane receptor activity
    		•  3.4815731203374 bayes_pls_golite062009
  • receptor activity
    		•  3.2014960162856 bayes_pls_golite062009
  • hydrolase activity
    		•  2.90276529968189 bayes_pls_golite062009
  • protein tyrosine/serine/threonine phosphatase activity
    		•  2.77531895423367 bayes_pls_golite062009
  • insulin receptor binding
    		•  2.63442848340688 bayes_pls_golite062009
  • protein serine/threonine phosphatase activity
    		•  2.49496709551693 bayes_pls_golite062009
  • signal transducer activity
    		•  2.27602678801224 bayes_pls_golite062009
  • molecular transducer activity
    		•  2.27602678801224 bayes_pls_golite062009
  • protein binding
    		•  2.12487185456363 bayes_pls_golite062009
  • binding
    		•  2.06015698112379 bayes_pls_golite062009
  • non-membrane spanning protein tyrosine phosphatase activity
    		•  2.04600549829086 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  1.56455764981613 bayes_pls_golite062009
  • kinase activity
    		•  1.54798529194457 bayes_pls_golite062009
  • cell adhesion molecule binding
    		•  1.53727496158735 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.38282868576714 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  1.36326098454926 bayes_pls_golite062009
  • protein kinase activity
    		•  1.3466747511896 bayes_pls_golite062009
  • DNA binding
    		•  1.31084450519924 bayes_pls_golite062009
  • transporter activity
    		•  1.21792561830727 bayes_pls_golite062009
  • inositol or phosphatidylinositol phosphatase activity
    		•  1.1200449509328 bayes_pls_golite062009
  • catalytic activity
    		•  1.06283028154109 bayes_pls_golite062009
  • transferase activity
    		•  1.05480035577492 bayes_pls_golite062009
  • lipid phosphatase activity
    		•  1.05085928819585 bayes_pls_golite062009
  • beta-catenin binding
    		•  1.02079992407668 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  1.00030784939308 bayes_pls_golite062009
  • kinase binding
    		•  0.95875467592478 bayes_pls_golite062009
  • delta-catenin binding
    		•  0.89195134506409 bayes_pls_golite062009
  • protein kinase binding
    		•  0.83725631602383 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.73846553033987 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.49044345981587 bayes_pls_golite062009
  • phospholipase binding
    		•  0.43589778800599 bayes_pls_golite062009
  • insulin receptor substrate binding
    		•  0.366350463194201 bayes_pls_golite062009
  • phosphatidylinositol trisphosphate phosphatase activity
    		•  0.28805451968625 bayes_pls_golite062009
  • peptide hormone receptor binding
    		•  0.272080084933271 bayes_pls_golite062009
  • gated channel activity
    		•  0.217548650508289 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.200180223985633 bayes_pls_golite062009
  • enzyme binding
    		•  0.150910330021054 bayes_pls_golite062009
  • receptor binding
    		•  0.0137204844761347 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle