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Protein Overview: CD81

General Information:
Name(s) found: CD81 [HGNC (HUGO)]
Description(s) found:
Found 34 descriptions.
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  • CD81 molecule [HGNC (HUGO)]
    • Organism: Homo sapiens
    Length: 236 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGVEGCTKCI KYLLFVFNFV FWLAGGVILG VALWLRHDPQ TTNLLYLELG DKPAPNTFYV  60
   61 GIYILIAVGA VMMFVGFLGC YGAIQESQCL LGTFFTCLVI LFACEVAAGI WGFVNKDQIA 120
  121 KDVKQFYDQA LQQAVVDDDA NNAKAVVKTF HETLDCCGSS TLTALTTSVL KNNLCPSGSN 180
  181 IISNLFKEDC HQKIDDLFSG KLYLIGIAAI VVAVIMIFEM ILSMVLCCGI RNSSVY

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..110] FFAS03 1.1 Acetylcholine receptor protein, delta chain
    2 View Details [111..236] PSI-BLAST 11.69897 CD81 extracellular domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • nicotinic acetylcholine-activated cation-selective channel activity
    		•  8.09774750177444 bayes_pls_golite062009
  • extracellular ligand-gated ion channel activity
    		•  6.8138989067086 bayes_pls_golite062009
  • excitatory extracellular ligand-gated ion channel activity
    		•  6.8138989067086 bayes_pls_golite062009
  • acetylcholine binding
    		•  6.04235159077861 bayes_pls_golite062009
  • gated channel activity
    		•  5.66609833149359 bayes_pls_golite062009
  • ligand-gated channel activity
    		•  5.65359564397775 bayes_pls_golite062009
  • ligand-gated ion channel activity
    		•  5.65359564397775 bayes_pls_golite062009
  • ion channel activity
    		•  5.59877286813906 bayes_pls_golite062009
  • cation channel activity
    		•  5.49725615782424 bayes_pls_golite062009
  • acetylcholine receptor activity
    		•  5.40168515414817 bayes_pls_golite062009
  • passive transmembrane transporter activity
    		•  4.88852337948775 bayes_pls_golite062009
  • channel activity
    		•  4.88852337948775 bayes_pls_golite062009
  • substrate-specific channel activity
    		•  4.75987274214331 bayes_pls_golite062009
  • metal ion transmembrane transporter activity
    		•  4.43671572548228 bayes_pls_golite062009
  • transporter activity
    		•  4.33216679738402 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  4.2745563261123 bayes_pls_golite062009
  • amine binding
    		•  4.25140819530684 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  4.19026880603966 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  4.14475572252231 bayes_pls_golite062009
  • transmembrane receptor activity
    		•  4.13892843658445 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  4.11908493779954 bayes_pls_golite062009
  • receptor activity
    		•  3.9625821847327 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  3.94631845574808 bayes_pls_golite062009
  • molecular transducer activity
    		•  3.87903570844696 bayes_pls_golite062009
  • signal transducer activity
    		•  3.87903570844696 bayes_pls_golite062009
  • chloride channel regulator activity
    		•  3.80555448212147 bayes_pls_golite062009
  • neurotransmitter binding
    		•  3.68173030115209 bayes_pls_golite062009
  • neurotransmitter receptor activity
    		•  3.59464831713762 bayes_pls_golite062009
  • toxin binding
    		•  2.56943469551261 bayes_pls_golite062009
  • binding
    		•  2.40028520341187 bayes_pls_golite062009
  • protein binding
    		•  1.46482989994288 bayes_pls_golite062009
  • drug binding
    		•  0.721991254175078 bayes_pls_golite062009
  • serotonin binding
    		•  0.707250780695203 bayes_pls_golite062009
  • serotonin-activated cation-selective channel activity
    		•  0.684758689525935 bayes_pls_golite062009
  • G-protein coupled receptor activity
    		•  0.35204430646141 bayes_pls_golite062009
  • kinase binding
    		•  0.292964438799031 bayes_pls_golite062009
    		• 0.269193639162997 bayes_pls_golite062009
  • protein kinase binding
    		•  0.267267173186573 bayes_pls_golite062009
  • channel regulator activity
    		•  0.252055844136184 bayes_pls_golite062009
  • adenylate cyclase binding
    		•  0.109562749490086 bayes_pls_golite062009
    2
    Term Confidence Notes
  • protein binding
    		•  1.71804056581958 bayes_pls_golite062009
  • binding
    		•  1.62531598262239 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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