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Protein Overview: ARG2

General Information:
Name(s) found: ARG2 [HGNC (HUGO)]
Description(s) found:
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  • gi|49168584|emb|CAG38787.1| ARG2 [Homo sapiens] [NCBI NR]
  • gi|4502215|ref|NP_001163.1| arginase 2 precursor [Homo sapiens] [NCBI NR]
  • gi|2492935|sp|P78540.1|ARGI2_HUMAN RecName: Full=Arginase-2, mitochondrial; Short=Arginase II; AltName: Full=Non-hepatic arginase; AltName: Full=Kidney-type arginase; Flags: Precursor [NCBI NR]
  • gi|20809781|gb|AAH29050.1| Arginase, type II [Homo sapiens] [NCBI NR]
  • gi|189065548|dbj|BAG35387.1| unnamed protein product [Homo sapiens] [NCBI NR]
  • gi|18535614|gb|AAL71548.1| arginase type II [Homo sapiens] [NCBI NR]
  • gi|1773059|gb|AAC51664.1| arginase type II [Homo sapiens] [NCBI NR]
  • gi|1763758|gb|AAB39855.1| arginase II [Homo sapiens] [NCBI NR]
  • gi|1694633|dbj|BAA13158.1| nonhepatic arginase [Homo sapiens] [NCBI NR]
  • gi|14250106|gb|AAH08464.1| Arginase, type II [Homo sapiens] [NCBI NR]
  • gi|12655005|gb|AAH01350.1| Arginase, type II [Homo sapiens] [NCBI NR]
  • gi|119601350|gb|EAW80944.1| arginase, type II, isoform CRA_a [Homo sapiens] [NCBI NR]
  • gi|119601349|gb|EAW80943.1| arginase, type II, isoform CRA_a [Homo sapiens] [NCBI NR]
  • arginase, type II [HGNC (HUGO)]
  • Arginase-2, mitochondrial OS=Homo sapiens GN=ARG2 PE=1 SV=1 [Swiss-Prot]
  • (P78540) Arginase II, mitochondrial precursor (EC 3.5.3.1) (Non-hepatic arginase) (Kidney-type arginase) [Swiss-Prot]
  • Arginase II, mitochondrial precursor [hmr_yeast5_DM3-1_pombe.fasta]
  • arginase, type II precursor; kidney arginase; nonhepatic arginase; L-arginine amidinohydrolase; L-arginine ureahydrolase; A-II [HMR_022704.fasta]
  • arginase, type II precursor; A-II; kidney arginase; nonhepatic arginase; L-arginine amidinohydrolase; L-arginine ureahydrolase [Human2242005.fasta]
  • arginase, type II precursor [Homo sapiens]gi|20809781|gb|AAH29050.1| Arginase, type II, precursor [Homo sapiens]gi|12655005|gb|AAH01350.1| Arginase, type II, precursor [Homo sapiens]gi|14250106|gb|AAH08464.1| Arginase, type II, precursor [Homo sapiens] [nrdb_11152004_Chlamydomonas]
  • Arginase II, mitochondrial precursor (Non-hepatic arginase) (Kidney-type arginase) [Yateslab_human_na_07-28-2006_reversed.fasta]
  • Tax_Id=9606 Arginase-2, mitochondrial precursor [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta]
  • (NM_001172) arginase, type II precursor; kidney arginase; nonhepatic arginase; L-arginine amidinohydrolase; L-arginine ureahydrolase; A-II [Homo sapiens] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • arginase, type II precursor [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta]
  • Tax_Id=9606 Arginase II, mitochondrial precursor [EBI-IPI_human_3.04_03-07-2005_reverse.fasta]
  • arginase, type II precursor; A-II; kidney arginase; nonhepatic arginase; L-arginine amidinohydrolase; L-arginine ureahydrolase [Homo sapiens] [HumanGallus06162005.fasta]
  • arginase, type II precursor; kidney arginase; nonhepatic arginase; L-arginine amidinohydrolase; L-arginine ureahydrolase; A-II [Homo sapiens] [human-NCBI-042104-rand.fasta]
  • Arginase-2, mitochondrial precursor (Arginase II) (Non-hepatic arginase) (Kidney-type arginase) [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • unnamed protein product [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • arginase, type II, isoform CRA_a [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • nonhepatic arginase [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Arginase, type II [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • ARG2 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • arginase type II [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • arginase II [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Tax_Id=9606 ARGINASE II, MITOCHONDRIAL PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • arginase 2 precursor [Homo sapiens] [NCBI-RefSeq_human-rat_na_04-07-2009_con_reversed.fasta]
  • Tax_Id=9606 Gene_Symbol=ARG2 Arginase-2, mitochondrial [human-ipi-250309-contam.fasta]
  • IPI:IPI00020332.1|SWISS-PROT:P78540|TREMBL:B2R690|ENSEMBL:ENSP00000261783|REFSEQ:NP_001163|H-INV:HIT000040668|VEGA:OTTHUMP00000028420 Tax_Id=9606 Gene_Symbol=ARG2 Arginase-2, mitochondrial [ipi.HUMAN.fasta.20090807]
  • [human_BMb_040710_contam.fasta]
  • Tax_Id=9606 Gene_Symbol=ARG2 Arginase-2, mitochondrial precursor ENSG00000081181 IPI00020332 [drosphohumanreversed.fasta]
  • Tax_Id=9606 Gene_Symbol=ARG2 Arginase-2, mitochondrial precursor [EBI-IPI_human_3.30_06-28-2007_con_reversed.fasta]
  • arginase-2, mitochondrial precursor [Homo sapiens] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta]
  • P78540;B2R690;Q6FHY8; RecName: Full=Arginase-2, mitochondrial; AltName: Full=Type II arginase; AltName: Full=Non-hepatic arginase; AltName: Full=Kidney-type arginase; Flags: Precursor; [UniProt_Human_2010_06_06-01-2010_reversed.fasta]
  • Arginase-2, mitochondrial OS=Homo sapiens GN=ARG2 [011711_HMR.fasta]
  • IPI:IPI00020332.1|SWISS-PROT:P78540|ENSEMBL:ENSP00000261783|REFSEQ:NP_001163|H-INV:HIT000040668|VEGA:OTTHUMP00000028420 Tax_Id=9606 Gene_Symbol=ARG2 Arginase-2, mitochondrial [ipi.HUMAN.fasta.20100406]
  • GeneSymbol=ARG2 Synonyms=- arginase-2, mitochondrial precursor [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta]
  • IPI:IPI00020332.1|SWISS-PROT:P78540|ENSEMBL:ENSP00000261783|REFSEQ:NP_001163|H-INV:HIT000040668 Tax_Id=9606 Gene_Symbol=ARG2 Arginase-2, mitochondrial [ipi.HUMAN.20110912.fasta]
  • Arginase-2, mitochondrial GN=ARG2 [Doctor+uniprot-HUMAN-120911.fasta]
  • Arginase OS=Homo sapiens GN=ARG2 PE=3 SV=1 [uniprot-human-031015-contam.fasta]
    • Organism: Homo sapiens
    Length: 354 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLRGSLSRL LQTRVHSILK KSVHSVAVIG APFSQGQKRK GVEHGPAAIR EAGLMKRLSS  60
   61 LGCHLKDFGD LSFTPVPKDD LYNNLIVNPR SVGLANQELA EVVSRAVSDG YSCVTLGGDH 120
  121 SLAIGTISGH ARHCPDLCVV WVDAHADINT PLTTSSGNLH GQPVSFLLRE LQDKVPQLPG 180
  181 FSWIKPCISS ASIVYIGLRD VDPPEHFILK NYDIQYFSMR DIDRLGIQKV MERTFDLLIG 240
  241 KRQRPIHLSF DIDAFDPTLA PATGTPVVGG LTYREGMYIA EEIHNTGLLS ALDLVEVNPQ 300
  301 LATSEEEAKT TANLAVDVIA SSFGQTREGG HIVYDQLPTP SSPDESENQA RVRI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..354] PSI-BLAST 103.0 Human Arginase II: Crystal Structure and Physiological Role in Male and Female Sexual Arousal

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • arginase activity
    		•  6.53441421234691 bayes_pls_golite062009
  • agmatinase activity
    		•  3.73238467801147 bayes_pls_golite062009
  • protein deacetylase activity
    		•  3.15425266272734 bayes_pls_golite062009
  • histone deacetylase activity
    		•  3.10913119405575 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.52770743634098 bayes_pls_golite062009
  • hydrolase activity
    		•  2.11707868768295 bayes_pls_golite062009
  • transcription factor binding
    		•  2.06538836131829 bayes_pls_golite062009
  • binding
    		•  1.948738669065 bayes_pls_golite062009
  • deacetylase activity
    		•  1.91016771390707 bayes_pls_golite062009
  • hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
    		•  1.72243397396987 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.70671280294121 bayes_pls_golite062009
  • catalytic activity
    		•  1.68836803454021 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.59562744871718 bayes_pls_golite062009
  • DNA binding
    		•  1.55288325159263 bayes_pls_golite062009
  • hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
    		•  1.01223037319069 bayes_pls_golite062009
  • transcription factor activity
    		•  0.882841288306625 bayes_pls_golite062009
  • protein binding
    		•  0.725535842743004 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.68008378742866 bayes_pls_golite062009
  • transcription corepressor activity
    		•  0.52929003055123 bayes_pls_golite062009
  • enzyme binding
    		•  0.39566582482721 bayes_pls_golite062009
  • specific transcriptional repressor activity
    		•  0.38389503761392 bayes_pls_golite062009
  • hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
    		•  0.0917282383800223 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle