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Protein Overview: YBX1

General Information:
Name(s) found: YBX1 [HGNC (HUGO)]
Description(s) found:
Found 45 descriptions.
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  • Y box binding protein 1 [HGNC (HUGO)]
    • Organism: Homo sapiens
    Length: 324 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSEAETQQP PAAPPAAPAL SAADTKPGTT GSGAGSGGPG GLTSAAPAGG DKKVIATKVL  60
   61 GTVKWFNVRN GYGFINRNDT KEDVFVHQTA IKKNNPRKYL RSVGDGETVE FDVVEGEKGA 120
  121 EAANVTGPGG VPVQGSKYAA DRNHYRRYPR RRGPPRNYQQ NYQNSESGEK NEGSESAPEG 180
  181 QAQQRRPYRR RRFPPYYMRR PYGRRPQYSN PPVQGEVMEG ADNQGAGEQG RPVRQNMYRG 240
  241 YRPRFRRGPP RQRQPREDGN EEDKENQGDE TQGQQPPQRR YRRNFNYRRR RPENPKPQDG 300
  301 KETKAADPPA ENSSAPEAEQ GGAE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run None Entered Sample pIC146 from april 2005 Okada, M., et al. (2006)
    View Run gi|14317902, gi|... No Comments Cheeseman, I.M., et al. (2004)
    View Run MIS12 No Comments Cheeseman, I.M., et al. (2004)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..128] PSI-BLAST 23.0 Y-box protein 1 cold shock domain (YB1-CSD)
    2 View Details [129..324] MSA 5.282996 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • nucleic acid binding
    		•  4.29626483284963 bayes_pls_golite062009
  • DNA binding
    		•  3.71771169141041 bayes_pls_golite062009
  • binding
    		•  2.83465364476231 bayes_pls_golite062009
  • RNA binding
    		•  2.41160981373213 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  2.36519400829041 bayes_pls_golite062009
  • single-stranded DNA binding
    		•  2.17275251213485 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.10110937001387 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  1.9581702424972 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.30343463892105 bayes_pls_golite062009
  • transcription activator activity
    		•  1.24141936405635 bayes_pls_golite062009
  • protein binding
    		•  1.20309946451799 bayes_pls_golite062009
  • transcription factor activity
    		•  1.14242112812892 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  1.04824459597896 bayes_pls_golite062009
    		• 0.966603287421221 bayes_pls_golite062009
  • ribonuclease activity
    		•  0.702449673647117 bayes_pls_golite062009
  • structural molecule activity
    		•  0.701736942766518 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  0.583085644017496 bayes_pls_golite062009
  • exoribonuclease activity, producing 5'-phosphomonoesters
    		•  0.449277083957511 bayes_pls_golite062009
  • mRNA binding
    		•  0.4162128308402 bayes_pls_golite062009
  • exoribonuclease activity
    		•  0.40223812695012 bayes_pls_golite062009
  • translation regulator activity
    		•  0.31332179848255 bayes_pls_golite062009
  • translation factor activity, nucleic acid binding
    		•  0.263197317040851 bayes_pls_golite062009
  • chromatin binding
    		•  0.19409870825073 bayes_pls_golite062009
  • 3'-5'-exoribonuclease activity
    		•  0.13299060447839 bayes_pls_golite062009
  • nuclease activity
    		•  0.111225677144242 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle