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Protein Overview: SIRT2

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

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[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data


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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#   Region(s) Method Confidence Match Description
1 View Details [1..389] PSI-BLAST 105.0 Sirt2 histone deacetylase

Functions predicted (by domain):

# Gene Ontology predictions
1
Term Confidence Notes
  • protein deacetylase activity
  • 9.15022242957651 bayes_pls_golite062009
  • histone deacetylase activity
  • 9.04876491350231 bayes_pls_golite062009
  • NAD-dependent protein deacetylase activity
  • 8.13038616303736 bayes_pls_golite062009
  • NAD-dependent histone deacetylase activity
  • 8.13038616303736 bayes_pls_golite062009
  • deacetylase activity
  • 8.11496387956068 bayes_pls_golite062009
  • hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
  • 5.83127897351395 bayes_pls_golite062009
  • NAD-dependent histone deacetylase activity (H3-K9 specific)
  • 5.29340754009793 bayes_pls_golite062009
  • NAD-dependent histone deacetylase activity (H3-K14 specific)
  • 5.29340754009793 bayes_pls_golite062009
  • tubulin deacetylase activity
  • 4.98963898611597 bayes_pls_golite062009
  • NAD+ ADP-ribosyltransferase activity
  • 4.62921662347995 bayes_pls_golite062009
  • NAD-dependent histone deacetylase activity (H4-K16 specific)
  • 3.89088174584308 bayes_pls_golite062009
  • histone deacetylase activity (H3-K9 specific)
  • 3.4896257195243 bayes_pls_golite062009
  • transcription regulator activity
  • 2.9155913558118 bayes_pls_golite062009
  • DNA binding
  • 2.43141001866996 bayes_pls_golite062009
  • nucleic acid binding
  • 2.41433477472968 bayes_pls_golite062009
  • transcription repressor activity
  • 2.24657784428979 bayes_pls_golite062009
  • binding
  • 2.06552694538163 bayes_pls_golite062009
  • histone binding
  • 1.71445510915336 bayes_pls_golite062009
  • histone deacetylase activity (H3-K14 specific)
  • 1.70314558948153 bayes_pls_golite062009
  • transcription corepressor activity
  • 1.64212790017753 bayes_pls_golite062009
  • protein binding
  • 1.52593340148652 bayes_pls_golite062009
  • nucleosome binding
  • 1.5125174755597 bayes_pls_golite062009
  • hydrolase activity
  • 1.43067365161346 bayes_pls_golite062009
  • hydrogen ion transmembrane transporter activity
  • 1.40719303660557 bayes_pls_golite062009
  • transcription factor activity
  • 1.30143289828088 bayes_pls_golite062009
  • monovalent inorganic cation transmembrane transporter activity
  • 1.26370407179255 bayes_pls_golite062009
  • transcription factor binding
  • 1.14766678956419 bayes_pls_golite062009
  • NAD(P)+-protein-arginine ADP-ribosyltransferase activity
  • 0.963519974868694 bayes_pls_golite062009
  • inorganic cation transmembrane transporter activity
  • 0.74741958699764 bayes_pls_golite062009
  • catalytic activity
  • 0.739210399081789 bayes_pls_golite062009
  • cation transmembrane transporter activity
  • 0.56434127203174 bayes_pls_golite062009
  • transcription cofactor activity
  • 0.54005617175343 bayes_pls_golite062009
  • hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
  • 0.114062221123972 bayes_pls_golite062009




    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.79

    Source: Reynolds et al. (2008)


    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle