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Protein Overview: ZNF281

General Information:
Name(s) found: ZNF281 [HGNC (HUGO)]
Description(s) found:
Found 33 descriptions.
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  • zinc finger protein 281 [HGNC (HUGO)]
    • Organism: Homo sapiens
    Length: 895 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKIGSGFLSG GGGTGSSGGS GSGGGGSGGG GGGGSSGRRA EMEPTFPQGM VMFNHRLPPV  60
   61 TSFTRPAGSA APPPQCVLSS STSAAPAAEP PPPPAPDMTF KKEPAASAAA FPSQRTSWGF 120
  121 LQSLVSIKQE KPADPEEQQS HHHHHHHHYG GLFAGAEERS PGLGGGEGGS HGVIQDLSIL 180
  181 HQHVQQQPAQ HHRDVLLSSS SRTDDHHGTE EPKQDTNVKK AKRPKPESQG IKAKRKPSAS 240
  241 SKPSLVGDGE GAILSPSQKP HICDHCSAAF RSSYHLRRHV LIHTGERPFQ CSQCSMGFIQ 300
  301 KYLLQRHEKI HSREKPFGCD QCSMKFIQKY HMERHKRTHS GEKPYKCDTC QQYFSRTDRL 360
  361 LKHRRTCGEV IVKGATSAEP GSSNHTNMGN LAVLSQGNTS SSRRKTKSKS IAIENKEQKT 420
  421 GKTNESQISN NINMQSYSVE MPTVSSSGGI IGTGIDELQK RVPKLIFKKG SRKNTDKNYL 480
  481 NFVSPLPDIV GQKSLSGKPS GSLGIVSNNS VETIGLLQST SGKQGQISSN YDDAMQFSKK 540
  541 RRYLPTASSN SAFSINVGHM VSQQSVIQSA GVSVLDNEAP LSLIDSSALN AEIKSCHDKS 600
  601 GIPDEVLQSI LDQYSNKSES QKEDPFNIAE PRVDLHTSGE HSELVQEENL SPGTQTPSND 660
  661 KASMLQEYSK YLQQAFEKST NASFTLGHGF QFVSLSSPLH NHTLFPEKQI YTTSPLECGF 720
  721 GQSVTSVLPS SLPKPPFGML FGSQPGLYLS ALDATHQQLT PSQELDDLID SQKNLETSSA 780
  781 FQSSSQKLTS QKEQKNLESS TGFQIPSQEL ASQIDPQKDI EPRTTYQIEN FAQAFGSQFK 840
  841 SGSRVPMTFI TNSNGEVDHR VRTSVSDFSG YTNMMSDVSE PCSTRVKTPT SQSYR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MIS12 No Comments Cheeseman, I.M., et al. (2004)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..90] FFAS03 1.02 Ribonuclease domain of colicin E3; Colicin E3 translocation domain; Colicin E3 receptor domain
    2 View Details [91..150] PSI-BLAST 15.30103 Transcription factor IIIA, TFIIIA
    3 View Details [151..347] PSI-BLAST 30.522879 No description for 2i13A was found.
    4 View Details [348..520] PSI-BLAST 8.522879 Five-finger GLI1
    5 View Details [521..723] deduced N/A No confident structure predictions are available.
    6 View Details [724..895] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • transcription regulator activity
    		•  4.70988788192472 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.58713908116892 bayes_pls_golite062009
  • DNA binding
    		•  4.56219307357342 bayes_pls_golite062009
  • transcription factor activity
    		•  3.50954949535763 bayes_pls_golite062009
  • transcription repressor activity
    		•  3.27542149084008 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  3.22082323675675 bayes_pls_golite062009
  • binding
    		•  3.10743787485868 bayes_pls_golite062009
  • transcription activator activity
    		•  2.19952417915035 bayes_pls_golite062009
  • chromatin binding
    		•  2.18464662431232 bayes_pls_golite062009
  • specific RNA polymerase II transcription factor activity
    		•  1.63161912031789 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  1.42975942698743 bayes_pls_golite062009
  • transcription factor binding
    		•  1.39608963544799 bayes_pls_golite062009
  • transcription corepressor activity
    		•  1.34049786451995 bayes_pls_golite062009
  • protein binding
    		•  1.00484935878505 bayes_pls_golite062009
  • transcription coactivator activity
    		•  0.912796194488319 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.77874411480713 bayes_pls_golite062009
  • catalytic activity
    		•  0.245893663605433 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.240825841910931 bayes_pls_golite062009
  • double-stranded DNA binding
    		•  0.0129353639725593 bayes_pls_golite062009
    3 No functions predicted.
    4
    Term Confidence Notes
  • transcription regulator activity
    		•  4.70988788192472 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.58713908116892 bayes_pls_golite062009
  • DNA binding
    		•  4.56219307357342 bayes_pls_golite062009
  • transcription factor activity
    		•  3.50954949535763 bayes_pls_golite062009
  • transcription repressor activity
    		•  3.27542149084008 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  3.22082323675675 bayes_pls_golite062009
  • binding
    		•  3.10743787485868 bayes_pls_golite062009
  • transcription activator activity
    		•  2.19952417915035 bayes_pls_golite062009
  • chromatin binding
    		•  2.18464662431232 bayes_pls_golite062009
  • specific RNA polymerase II transcription factor activity
    		•  1.63161912031789 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  1.42975942698743 bayes_pls_golite062009
  • transcription factor binding
    		•  1.39608963544799 bayes_pls_golite062009
  • transcription corepressor activity
    		•  1.34049786451995 bayes_pls_golite062009
  • protein binding
    		•  1.00484935878505 bayes_pls_golite062009
  • transcription coactivator activity
    		•  0.912796194488319 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.77874411480713 bayes_pls_golite062009
  • catalytic activity
    		•  0.245893663605433 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.240825841910931 bayes_pls_golite062009
  • double-stranded DNA binding
    		•  0.0129353639725593 bayes_pls_golite062009
    5 No functions predicted.
    6 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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