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Protein Overview: gi|55959718, gi|...

General Information:
Name(s) found: gi|55959718 [NCBI NR]
gi|55661763 [NCBI NR]
gi|55661528 [NCBI NR]
gi|55661174 [NCBI NR]
gi|4758128 [NCBI NR]
gi|156230969 [NCBI NR]
gi|119628955 [NCBI NR]
Description(s) found:
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  • gi|55959718|emb|CAI15720.1| doublecortin and CaM kinase-like 1 [Homo sapiens] [NCBI NR]
  • gi|55661763|emb|CAH70262.1| doublecortin and CaM kinase-like 1 [Homo sapiens] [NCBI NR]
  • gi|55661528|emb|CAH70168.1| doublecortin and CaM kinase-like 1 [Homo sapiens] [NCBI NR]
  • gi|55661174|emb|CAH70657.1| doublecortin and CaM kinase-like 1 [Homo sapiens] [NCBI NR]
  • gi|4758128|ref|NP_004725.1| doublecortin-like kinase 1 [Homo sapiens] [NCBI NR]
  • gi|156230969|gb|AAI52457.1| Doublecortin-like kinase 1 [Homo sapiens] [NCBI NR]
  • gi|119628955|gb|EAX08550.1| doublecortin and CaM kinase-like 1, isoform CRA_a [Homo sapiens] [NCBI NR]
  • Splice isoform 1 of O15075 Serine/threonine-protein kinase DCAMKL1 [hmr_yeast5_DM3-1_pombe.fasta]
  • doublecortin and CaM kinase-like 1; doublecortin-like kinase [HMR_022704.fasta]
  • doublecortin and CaM kinase-like 1 [Homo sapiens]gi|55661763|emb|CAH70262.1| doublecortin and CaM kinase-like 1 [Homo sapiens]gi|55661528|emb|CAH70168.1| doublecortin and CaM kinase-like 1 [Homo sapiens]gi|55661174|emb|CAH70657.1| doublecortin and CaM [nrdb_11152004_Chlamydomonas]
  • Tax_Id=9606 Splice Isoform 1 of Serine/threonine-protein kinase DCAMKL1 [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta]
  • (NM_004734) doublecortin and CaM kinase-like 1; doublecortin-like kinase [Homo sapiens] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • doublecortin and CaM kinase-like 1 [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta]
  • doublecortin and CaM kinase-like 1; doublecortin-like kinase [Homo sapiens] [HumanGallus06162005.fasta]
  • Doublecortin-like kinase 1 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • doublecortin and CaM kinase-like 1, isoform CRA_a [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Tax_Id=9606 Isoform 1 of Serine/threonine-protein kinase DCAMKL1 [EBI-IPI_human_3.23_11-02-2006_con_reversed.fasta]
  • Tax_Id=9606 SPLICE ISOFORM 2 OF SERINE/THREONINE-PROTEIN KINASE DCAMKL1 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • Tax_Id=9606 Gene_Symbol=DCLK1 Isoform 1 of Serine/threonine-protein kinase DCLK1 [human-ipi-250309-contam.fasta]
  • doublecortin-like kinase 1 [Homo sapiens] [NCBI-RefSeq_human_na_07-13-2009_con_reversed.fasta]
  • IPI:IPI00217247.1|SWISS-PROT:O15075-2|TREMBL:B7Z2T7|ENSEMBL:ENSP00000255448|REFSEQ:NP_004725|H-INV:HIT000000075|VEGA:OTTHUMP00000018250 Tax_Id=9606 Gene_Symbol=DCLK1 Isoform 1 of Serine/threonine-protein kinase DCLK1 [ipi.HUMAN.fasta.20090807]
  • [human_BMb_040710_contam.fasta]
  • serine/threonine-protein kinase DCLK1 [Homo sapiens] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta]
  • Isoform 1 of Serine/threonine-protein kinase DCLK1 OS=Homo sapiens GN=DCLK1 [011711_HMR.fasta]
  • GeneSymbol=DCLK1 Synonyms=CL1|CLICK1|DCAMKL1|DCDC3A|DCLK|KIAA0369 serine/threonine-protein kinase DCLK1 [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta]
  • IPI:IPI00217247.1|SWISS-PROT:O15075-2|ENSEMBL:ENSP00000255448|REFSEQ:NP_004725|H-INV:HIT000000075|VEGA:OTTHUMP00000018250 Tax_Id=9606 Gene_Symbol=DCLK1 Isoform 1 of Serine/threonine-protein kinase DCLK1 [ipi.HUMAN.20110912.fasta]
  • Isoform 1 of Serine/threonine-protein kinase DCLK1 GN=DCLK1 [Doctor+uniprot-HUMAN-120911.fasta]
  • Isoform of O15075, Isoform 1 of Serine/threonine-protein kinase DCLK1 OS=Homo sapiens GN=DCLK1 [2016-04-human-contam-aPKC-His-Par6.fasta]
    • Organism: Homo sapiens
    Length: 729 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSFGRDMELE HFDERDKAQR YSRGSRVNGL PSPTHSAHCS FYRTRTLQTL SSEKKAKKVR  60
   61 FYRNGDRYFK GIVYAISPDR FRSFEALLAD LTRTLSDNVN LPQGVRTIYT IDGLKKISSL 120
  121 DQLVEGESYV CGSIEPFKKL EYTKNVNPNW SVNVKTTSAS RAVSSLATAK GSPSEVRENK 180
  181 DFIRPKLVTI IRSGVKPRKA VRILLNKKTA HSFEQVLTDI TDAIKLDSGV VKRLYTLDGK 240
  241 QVMCLQDFFG DDDIFIACGP EKFRYQDDFL LDESECRVVK STSYTKIASS SRRSTTKSPG 300
  301 PSRRSKSPAS TSSVNGTPGS QLSTPRSGKS PSPSPTSPGS LRKQRSSQHG GSSTSLASTK 360
  361 VCSSMDENDG PGEEVSEEGF QIPATITERY KVGRTIGDGN FAVVKECVER STAREYALKI 420
  421 IKKSKCRGKE HMIQNEVSIL RRVKHPNIVL LIEEMDVPTE LYLVMELVKG GDLFDAITST 480
  481 NKYTERDASG MLYNLASAIK YLHSLNIVHR DIKPENLLVY EHQDGSKSLK LGDFGLATIV 540
  541 DGPLYTVCGT PTYVAPEIIA ETGYGLKVDI WAAGVITYIL LCGFPPFRGS GDDQEVLFDQ 600
  601 ILMGQVDFPS PYWDNVSDSA KELITMMLLV DVDQRFSAVQ VLEHPWVNDD GLPENEHQLS 660
  661 VAGKIKKHFN TGPKPNSTAA GVSVIALDHG FTIKRSGSLD YYQQPGMYWI RPPLLIRRGR 720
  721 FSDEDATRM

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..162] PSI-BLAST 14.522879 Solution structure of the N-terminal DCX domain of human doublecortin-like kinase
    2 View Details [163..278] FFAS03 4.71 No description for 2dnfA was found.
    3 View Details [279..384] deduced N/A No confident structure predictions are available.
    4 View Details [385..729] PSI-BLAST 72.69897 CALMODULIN-DEPENDENT PROTEIN KINASE FROM RAT

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • microtubule binding
    		•  4.10505919994779 bayes_pls_golite062009
  • tubulin binding
    		•  4.10098975798325 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  3.08898918847458 bayes_pls_golite062009
  • binding
    		•  1.95079397144714 bayes_pls_golite062009
  • protein binding
    		•  0.476896736636797 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4
    Term Confidence Notes
  • protein kinase activity
    		•  5.4586557943719 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  5.04467222534257 bayes_pls_golite062009
  • kinase activity
    		•  4.85903980916957 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  4.63692708178478 bayes_pls_golite062009
  • protein serine/threonine kinase activity
    		•  4.46381887831481 bayes_pls_golite062009
  • calmodulin-dependent protein kinase activity
    		•  4.31938467136214 bayes_pls_golite062009
  • transferase activity
    		•  3.26787750561728 bayes_pls_golite062009
  • signal transducer activity
    		•  2.85730457922199 bayes_pls_golite062009
  • molecular transducer activity
    		•  2.85730457922199 bayes_pls_golite062009
  • protein tyrosine kinase activity
    		•  2.8153155526437 bayes_pls_golite062009
  • telethonin binding
    		•  2.81155575828766 bayes_pls_golite062009
  • binding
    		•  2.74863538127007 bayes_pls_golite062009
  • transmembrane receptor activity
    		•  2.28919522845509 bayes_pls_golite062009
  • tubulin binding
    		•  2.18641675163967 bayes_pls_golite062009
  • receptor activity
    		•  2.14074739723463 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  2.12615078788254 bayes_pls_golite062009
  • receptor signaling protein activity
    		•  2.10379226653669 bayes_pls_golite062009
  • ATP binding
    		•  1.97600611746091 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  1.93596671856664 bayes_pls_golite062009
  • alpha-actinin binding
    		•  1.92962505218614 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  1.90928021591891 bayes_pls_golite062009
  • phosphoinositide 3-kinase binding
    		•  1.90879495821405 bayes_pls_golite062009
  • microtubule binding
    		•  1.88110801192607 bayes_pls_golite062009
  • receptor signaling protein serine/threonine kinase activity
    		•  1.81249386965144 bayes_pls_golite062009
  • transmembrane receptor protein kinase activity
    		•  1.7769021678395 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  1.65732943334212 bayes_pls_golite062009
  • ribonucleotide binding
    		•  1.65726906484847 bayes_pls_golite062009
  • purine nucleotide binding
    		•  1.63763394711025 bayes_pls_golite062009
  • nucleotide binding
    		•  1.63195828048121 bayes_pls_golite062009
  • transmembrane receptor protein tyrosine kinase activity
    		•  1.4571078357189 bayes_pls_golite062009
  • actin binding
    		•  1.33479685165255 bayes_pls_golite062009
  • transforming growth factor beta receptor activity
    		•  1.33329180203433 bayes_pls_golite062009
  • transmembrane receptor protein serine/threonine kinase activity
    		•  1.33329180203433 bayes_pls_golite062009
  • gamma-tubulin binding
    		•  1.28511591054866 bayes_pls_golite062009
  • protein binding
    		•  1.22565748038754 bayes_pls_golite062009
  • catalytic activity
    		•  1.21655087018101 bayes_pls_golite062009
  • transporter activity
    		•  1.11833481501707 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  0.97575992765505 bayes_pls_golite062009
  • insulin receptor activity
    		•  0.974517002259609 bayes_pls_golite062009
  • transmembrane-ephrin receptor activity
    		•  0.971682315034679 bayes_pls_golite062009
  • transforming growth factor beta receptor activity, type I
    		•  0.880236579821909 bayes_pls_golite062009
  • activin receptor activity
    		•  0.811117252475389 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.705905455086486 bayes_pls_golite062009
  • structural constituent of cytoskeleton
    		•  0.612883428421652 bayes_pls_golite062009
  • cyclin-dependent protein kinase activity
    		•  0.499492353295369 bayes_pls_golite062009
  • activin binding
    		•  0.465961724597021 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.450699332958421 bayes_pls_golite062009
  • magnesium ion binding
    		•  0.393328812780268 bayes_pls_golite062009
  • PTB domain binding
    		•  0.384625387464921 bayes_pls_golite062009
  • kinase binding
    		•  0.26752427107238 bayes_pls_golite062009
  • actin filament binding
    		•  0.2403700250846 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.148194101970458 bayes_pls_golite062009
  • activin receptor activity, type I
    		•  0.117759584117941 bayes_pls_golite062009
  • MAP kinase activity
    		•  0.08504542461349 bayes_pls_golite062009
  • growth factor binding
    		•  0.0526340287295695 bayes_pls_golite062009
  • fibroblast growth factor receptor activity
    		•  0.00836512390788968 bayes_pls_golite062009
  • protein kinase binding
    		•  0.00674998152095019 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  0.0040394359628233 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle