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Protein Overview: gi|468497, gi|21...

General Information:
Name(s) found: gi|468497 [NCBI NR]
gi|4557755 [NCBI NR]
gi|40807040 [NCBI NR]
gi|2135745 [NCBI NR]
gi|119585887 [NCBI NR]
Description(s) found:
Found 25 descriptions.
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  • gi|468497|emb|CAA82775.1| MITF protein [Homo sapiens] [NCBI NR]
  • gi|4557755|ref|NP_000239.1| microphthalmia-associated transcription factor isoform 4 [Homo sapiens] [NCBI NR]
  • gi|40807040|gb|AAH65243.1| Microphthalmia-associated transcription factor [Homo sapiens] [NCBI NR]
  • pir||I38024 MITF protein - human [NCBI NR]
  • gi|119585887|gb|EAW65483.1| microphthalmia-associated transcription factor, isoform CRA_e [Homo sapiens] [NCBI NR]
    • Organism: Homo sapiens
    Length: 419 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLEMLEYNHY QVQTHLENPT KYHIQQAQRQ QVKQYLSTTL ANKHANQVLS LPCPNQPGDH  60
   61 VMPPVPGSSA PNSPMAMLTL NSNCEKEGFY KFEEQNRAES ECPGMNTHSR ASCMQMDDVI 120
  121 DDIISLESSY NEEILGLMDP ALQMANTLPV SGNLIDLYGN QGLPPPGLTI SNSCPANLPN 180
  181 IKRELTACIF PTESEARALA KERQKKDNHN LIERRRRFNI NDRIKELGTL IPKSNDPDMR 240
  241 WNKGTILKAS VDYIRKLQRE QQRAKELENR QKKLEHANRH LLLRIQELEM QARAHGLSLI 300
  301 PSTGLCSPDL VNRIIKQEPV LENCSQDLLQ HHADLTCTTT LDLTDGTITF NNNLGTGTEA 360
  361 NQAYSVPTKM GSKLEDILMD DTLSPVGVTD PLLSSVSPGA SKTSSRRSSM SMEETEHTC

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..198] MSA 5.639997 View MSA. No confident structure predictions are available.
    2 View Details [199..298] PSI-BLAST 17.522879 Myc prot-oncogene protein
    3 View Details [299..419] MSA 3.372993 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • transcription regulator activity
    		•  5.38658950816179 bayes_pls_golite062009
  • DNA binding
    		•  5.18654839258297 bayes_pls_golite062009
  • nucleic acid binding
    		•  5.05768805749761 bayes_pls_golite062009
  • transcription factor activity
    		•  4.78039531631248 bayes_pls_golite062009
  • transcription activator activity
    		•  3.87875547821718 bayes_pls_golite062009
  • binding
    		•  3.81829206350975 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  3.42035985454056 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  3.39500382187264 bayes_pls_golite062009
  • protein binding
    		•  2.64975291677725 bayes_pls_golite062009
  • transcription factor binding
    		•  2.61163564741984 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity, enhancer binding
    		•  2.42306484786159 bayes_pls_golite062009
  • promoter binding
    		•  1.56457725225443 bayes_pls_golite062009
  • transcription cofactor activity
    		•  1.52770895937238 bayes_pls_golite062009
  • transcription coactivator activity
    		•  1.39260472877067 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.955588849035129 bayes_pls_golite062009
  • transcription corepressor activity
    		•  0.801830750183111 bayes_pls_golite062009
  • protein heterodimerization activity
    		•  0.53175615551166 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.3655541712365 bayes_pls_golite062009
  • double-stranded DNA binding
    		•  0.29436315000437 bayes_pls_golite062009
  • protein dimerization activity
    		•  0.20674648626116 bayes_pls_golite062009
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle