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Protein Overview: ATG4A

General Information:
Name(s) found: ATG4A [HGNC (HUGO)]
Description(s) found:
Found 38 descriptions.
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  • ATG4 autophagy related 4 homolog A (S. cerevisiae) [HGNC (HUGO)]
    • Organism: Homo sapiens
    Length: 398 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MESVLSKYED QITIFTDYLE EYPDTDELVW ILGKQHLLKT EKSKLLSDIS ARLWFTYRRK  60
   61 FSPIGGTGPS SDAGWGCMLR CGQMMLAQAL ICRHLGRDWS WEKQKEQPKE YQRILQCFLD 120
  121 RKDCCYSIHQ MAQMGVGEGK SIGEWFGPNT VAQVLKKLAL FDEWNSLAVY VSMDNTVVIE 180
  181 DIKKMCRVLP LSADTAGDRP PDSLTASNQS KGTSAYCSAW KPLLLIVPLR LGINQINPVY 240
  241 VDAFKECFKM PQSLGALGGK PNNAYYFIGF LGDELIFLDP HTTQTFVDTE ENGTVNDQTF 300
  301 HCLQSPQRMN ILNLDPSVAL GFFCKEEKDF DNWCSLVQKE ILKENLRMFE LVQKHPSHWP 360
  361 PFVPPAKPEV TTTGAEFIDS TEQLEEFDLE EDFEILSV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..398] PSI-BLAST 155.0 No description for 2p82A was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • peptidase activity
    		•  4.90619850296986 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  4.64381885397949 bayes_pls_golite062009
  • endopeptidase activity
    		•  3.75054525912786 bayes_pls_golite062009
  • cysteine-type peptidase activity
    		•  3.05412701733177 bayes_pls_golite062009
  • hydrolase activity
    		•  2.66167923792227 bayes_pls_golite062009
  • binding
    		•  2.49172648273202 bayes_pls_golite062009
  • small conjugating protein-specific protease activity
    		•  2.06332547782769 bayes_pls_golite062009
  • cysteine-type endopeptidase activity
    		•  1.95802900199539 bayes_pls_golite062009
  • microtubule binding
    		•  1.80986894246631 bayes_pls_golite062009
  • tubulin binding
    		•  1.65326788939069 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  1.61845762872724 bayes_pls_golite062009
  • ubiquitin-specific protease activity
    		•  1.43988355875744 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.38318152877128 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.34325826373515 bayes_pls_golite062009
  • DNA binding
    		•  1.31096468235949 bayes_pls_golite062009
  • catalytic activity
    		•  1.05972260874031 bayes_pls_golite062009
  • protein binding
    		•  0.774177093888744 bayes_pls_golite062009
  • transcription activator activity
    		•  0.725305894454674 bayes_pls_golite062009
  • transporter activity
    		•  0.69523261160023 bayes_pls_golite062009
  • transcription factor activity
    		•  0.656405451523439 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.467924587720185 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  0.439003000540428 bayes_pls_golite062009
  • structural molecule activity
    		•  0.297752217869698 bayes_pls_golite062009
  • calcium-dependent cysteine-type endopeptidase activity
    		•  0.196538841514154 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.125654358663332 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  0.0241561776323942 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle