Protein Overview: SF3A3

General Information:
Name(s) found:	SF3A3 [HGNC (HUGO)]
Description(s) found: SHOW ONLY BEST	gi\|5803167\|ref\|NP_006793.1\| splicing factor 3a, subunit 3 [Homo sapiens] [NCBI NR] gi\|55665971\|emb\|CAH69930.1\| splicing factor 3a, subunit 3, 60kDa [Homo sapiens] [NCBI NR] gi\|508723\|gb\|AAA19625.1\| SAP 61 [NCBI NR] gi\|17380310\|sp\|Q12874.1\|SF3A3_HUMAN RecName: Full=Splicing factor 3A subunit 3; AltName: Full=Spliceosome-associated protein 61; Short=SAP 61; AltName: Full=SF3a60 [NCBI NR] gi\|15079355\|gb\|AAH11523.1\| Splicing factor 3a, subunit 3, 60kDa [Homo sapiens] [NCBI NR] gi\|12803179\|gb\|AAH02395.1\| Splicing factor 3a, subunit 3, 60kDa [Homo sapiens] [NCBI NR] gi\|119627710\|gb\|EAX07305.1\| splicing factor 3a, subunit 3, 60kDa, isoform CRA_a [Homo sapiens] [NCBI NR] gi\|119627709\|gb\|EAX07304.1\| splicing factor 3a, subunit 3, 60kDa, isoform CRA_a [Homo sapiens] [NCBI NR] pir\|\|A55749 spliceosome-associated protein SAP 61 - human [NCBI NR] splicing factor 3a, subunit 3, 60kDa [HGNC (HUGO)] Splicing factor 3A subunit 3 OS=Homo sapiens GN=SF3A3 PE=1 SV=1 [Swiss-Prot] (Q12874) Splicing factor 3A subunit 3 (Spliceosome associated protein 61) (SAP 61) (SF3a60) [Swiss-Prot] Splicing factor 3A subunit 3 [hmr_yeast5_DM3-1_pombe.fasta] splicing factor 3a, subunit 3, 60kDa; pre-mRNA splicing factor SF3a (60kD) [HMR_022704.fasta] splicing factor 3a, subunit 3 [Homo sapiens]gi\|55665971\|emb\|CAH69930.1\| splicing factor 3a, subunit 3, 60kDa [Homo sapiens]gi\|12803179\|gb\|AAH02395.1\| Splicing factor 3a, subunit 3, 60kDa [Homo sapiens]gi\|15079355\|gb\|AAH11523.1\| Splicing factor 3a, subu [nrdb_11152004_Chlamydomonas] Splicing factor 3A subunit 3 (Spliceosome associated protein 61) (SAP 61) (SF3a60) [Yateslab_human_na_07-28-2006_reversed.fasta] Tax_Id=9606 Splicing factor 3A subunit 3 [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta] (NM_006802) splicing factor 3a, subunit 3, 60kD; pre-mRNA splicing factor SF3a (60kD), similar to S. cerevisiae PRP9 (spliceosome-associated protein 61) [Homo sapiens] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] splicing factor 3a, subunit 3 [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta] splicing factor 3a, subunit 3, 60kDa; pre-mRNA splicing factor SF3a (60kD) [Homo sapiens] [HumanGallus06162005.fasta] Splicing factor 3A subunit 3 (Spliceosome-associated protein 61) (SAP 61) (SF3a60) [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] splicing factor 3a, subunit 3, 60kDa [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] splicing factor 3a, subunit 3, 60kDa, isoform CRA_a [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] Splicing factor 3a, subunit 3, 60kDa [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] SAP 61 [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] Tax_Id=9606 SPLICING FACTOR 3A SUBUNIT 3 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=9606 Gene_Symbol=SF3A3 Splicing factor 3A subunit 3 [human-ipi-250309-contam.fasta] IPI:IPI00029764.1\|SWISS-PROT:Q12874\|TREMBL:A8K566;A8K7V1;B3KY12;Q53HM6\|ENSEMBL:ENSP00000362110\|REFSEQ:NP_006793\|H-INV:HIT000217844\|VEGA:OTTHUMP00000004730 Tax_Id=9606 Gene_Symbol=SF3A3 Splicing factor 3A subunit 3 [ipi.HUMAN.fasta.20090807] [human_BMb_040710_contam.fasta] Tax_Id=9606 Gene_Symbol=SF3A3 Splicing factor 3A subunit 3 ENSG00000183431 IPI00029764 IPI00847972 [drosphohumanreversed.fasta] splicing factor 3A subunit 3 [Homo sapiens] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta] Q12874;Q15460;Q5VT87; RecName: Full=Splicing factor 3A subunit 3; AltName: Full=Spliceosome-associated protein 61; AltName: Full=SF3a60; [UniProt_Human_2010_06_06-01-2010_reversed.fasta] Splicing factor 3A subunit 3 OS=Homo sapiens GN=SF3A3 [011711_HMR.fasta] IPI:IPI00029764.1\|SWISS-PROT:Q12874\|TREMBL:A8K566;A8K7V1;B3KY12;D3DPT5;Q53HM6\|ENSEMBL:ENSP00000362110\|REFSEQ:NP_006793\|H-INV:HIT000217844\|VEGA:OTTHUMP00000004730 Tax_Id=9606 Gene_Symbol=SF3A3 Splicing factor 3A subunit 3 [ipi.HUMAN.fasta.20100406] Splicing factor 3A subunit 3 n=27 Tax=Euteleostomi RepID=SF3A3_HUMAN [UniProt_Xenopus_laevis_01-01-2011_reversed.fasta] GeneSymbol=SF3A3 Synonyms=PRP9\|PRPF9\|SAP61\|SF3a60 splicing factor 3A subunit 3 [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta] Splicing factor 3A subunit 3 GN=SF3A3 [Doctor+uniprot-HUMAN-120911.fasta]
Organism:	Homo sapiens
Length:	501 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	NONE FOUND
Molecular Function:	NONE FOUND

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 METILEQQRR YHEEKERLMD VMAKEMLTKK STLRDQINSD HRTRAMQDRY MEVSGNLRDL  60
   61 YDDKDGLRKE ELNAISGPNE FAEFYNRLKQ IKEFHRKHPN EICVPMSVEF EELLKARENP 120
  121 SEEAQNLVEF TDEEGYGRYL DLHDCYLKYI NLKASEKLDY ITYLSIFDQL FDIPKERKNA 180
  181 EYKRYLEMLL EYLQDYTDRV KPLQDQNELF GKIQAEFEKK WENGTFPGWP KETSSALTHA 240
  241 GAHLDLSAFS SWEELASLGL DRLKSALLAL GLKCGGTLEE RAQRLFSTKG KSLESLDTSL 300
  301 FAKNPKSKGT KRDTERNKDI AFLEAQIYEY VEILGEQRHL THENVQRKQA RTGEEREEEE 360
  361 EEQISESESE DEENEIIYNP KNLPLGWDGK PIPYWLYKLH GLNINYNCEI CGNYTYRGPK 420
  421 AFQRHFAEWR HAHGMRCLGI PNTAHFANVT QIEDAVSLWA KLKLQKASER WQPDTEEEYE 480
  481 DSSGNVVNKK TYEDLKRQGL L

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	MIS12	No Comments	Cheeseman, I.M., et al. (2004)

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..219]	MSA	2.038948	View MSA. No confident structure predictions are available.
2	View Details	[220..294]	MSA	13.053996	View MSA. No confident structure predictions are available.
3	View Details	[295..376]	deduced	N/A	No confident structure predictions are available.
4	View Details	[377..501]	FFAS03	1.05	Solution Structure of a Human C2H2-type Zinc Finger Protein

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: SF3A3

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: