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Protein Overview: SPO22

General Information:
Name(s) found: SPO22 / YIL073C [SGD]
Description(s) found:
Found 20 descriptions.
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  • Meiosis-specific protein essential for chromosome synapsis, involved in completion of nuclear divisions during meiosis; induced early in meiosis [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 975 amino acids

    Gene Ontology:
    Cellular Component: nuclear chromosome [IDALink to PubMed article]
    Biological Process: synaptonemal complex assembly [IMPLink to PubMed article]
    synapsis [IMPLink to PubMed article]
    meiosis [IEPLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDHNVNSTF RKTLVELCET ATWITSQVYA AKNLEKNDLI TVDNKISALY PIAEKYDRSF  60
   61 RTTTVILDEE LILKLENAAS SLWNSLTIAM KAEKASDKYF NEVFCKCKIF ATKLLSIHEA 120
  121 LFRTNTNLLR NFKCYISSFK SASEYRFDDL ITNTQQHSEK YLQIINENVE SFSNEEKTEF 180
  181 KKLTFEFYLV NFQLYLSEND LDTANIYTAK VNITDNSKYM DADLLIELCR MIYNSTVMLK 240
  241 EINNPETQLV DVNIISFLKD VEKYLELPVE NLKSHTDYSN LKYSVLIFMA NCLVEGHPQA 300
  301 SELEQCDHYL SLLQNEYPNK VDPFILAINL TKRRNIVNPA ETIEEILMRM IMSVDVISNF 360
  361 QAVIASINDL SKMNTKFSIV CLDYLLINKL NSKNDSKFLG KAICSRFLIT TQSKTMNDSE 420
  421 IAESLENFST QMERIVSEPL TKHAISCIIT LLWNTGKKLE KMEKYVVSIR FYKLALKDII 480
  481 SQNYSDRGKI QRALQVVYNK IEDYSNTVRV YQDMDEVDRQ SPLCQLLMLQ SFLADDKTEE 540
  541 ALTCLQKIKS SEDEKSTDAL ILAVAECKRK TDLSVQGLLM IFDKLQSKSN SQTISSTSSS 600
  601 QTLSILRYTL QMIVKVSEEE PLETFINYLP TVQKLLQKAV EFLKTVKLLN QLPPDVEKEA 660
  661 IYQQSVAVNE IEWFASFSYN VAVKCLVDQS CESISEFPQY CIQFIDLIPV QDFTFPKMYH 720
  721 FTYWRFKATI LQLIIAKEKA KQDQHQKDWD IYEKSEELVN SINVMKKSSE FKDGSSLEDR 780
  781 NTLHECFLEA LTIHLESALM MPDQTRILDI LKKTELYQDS RVDALLIDIS SNMEDLPKGV 840
  841 LIEILETVLK RNMGPEVKER ELCSWLRILL ENAINLNHEV ELRILDRVLK ILNINQSSLQ 900
  901 DTDGVLQTEL ETIATYCWNI GVNYIIKDNK SNGIVWCKHS MGFANMVNEG LQEQLYSLWE 960
  961 SLASSANIDI NSIAK

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Qiu et al. (2008) CST9 SPO22

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..220] deduced N/A No confident structure predictions are available.
    2 View Details [221..603] PSI-BLAST 17.39794 The superhelical TPR domain of O-linked GlcNAc transferase reveals structural similarities to importin alpha.
    3 View Details [604..815] deduced N/A No confident structure predictions are available.
    4 View Details [816..975] MSA 1.028992 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • binding
    		•  2.57186536498101 bayes_pls_golite062009
  • protein binding
    		•  1.83529176977066 bayes_pls_golite062009
  • transcription factor binding
    		•  0.350910388473439 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.1539868026804 bayes_pls_golite062009
    3 No functions predicted.
    4 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle