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Protein Overview: CST9

General Information:
Name(s) found: CST9 / YLR394W [SGD]
Description(s) found:
Found 25 descriptions.
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  • SUMO E3 ligase; required for synaptonemal complex formation; localizes to synapsis initiation sites on meiotic chromosomes; potential Cdc28p substrate [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 482 amino acids

    Gene Ontology:
    Cellular Component: nuclear chromosome [IDALink to PubMed article]
    Biological Process: protein sumoylation [IDALink to PubMed article][IMPLink to PubMed article]
    synaptonemal complex assembly [IMPLink to PubMed articleLink to PubMed article][IPILink to PubMed article]
    synapsis [IGILink to PubMed article][IMPLink to PubMed article]
    Molecular Function: SUMO ligase activity [IDALink to PubMed article][IMPLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGGYLAIVFI PQTNTKSMRE KKQKCLKQVR RLSLISPKKY IMPDSIFEQP FVYCGVCHRR  60
   61 TSHGDPLRLT SCAHILCSQH SPLTSKVCPI CRSSDISIIN LVESKQLPTD IRIFFEPLPP 120
  121 LLESLYNVSQ FQLNGLSKQC QYYQNHCLKL REKCARQQQL LYQAKIELDS MAILKKRIQE 180
  181 LESVLNHNNV SSMSVGVLPT RNSHQNHYQP PPTVDLTVDD NSLEEFEAKS FIKKLKKNSS 240
  241 LRNSSKNNNG TVTPSTSGRV NKNQPLFMET LNNPNRNSIP PPGMNPNANS NLPNISTIAE 300
  301 STNLNRFSFS PVRVAKGFDG KLPNLDILTN NGSVSSKNIS RLSSASLQPS SPLSSSSNRL 360
  361 ILPNSNLKEL HHSNTPLTST STQFPSALEK LKITRKRNNT ISGSNRITHN LSSHVRSSGL 420
  421 AFSSSSNSLQ QSKLPKSNIL KRSNSTQQLT NTHLKSDNHL PPRSSNTVLG SSKKNNKFRR 480
  481 IR

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Qiu et al. (2008) CST9 NFI1 SIZ1 SPO22

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #24 Asynchronous Prep3-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..188] ORFEUS 7.39 bard1 RING domain
    2 View Details [189..482] deduced N/A No confident structure predictions are available.
    3 View Details [284..482] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle