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View Structure Prediction Details

Protein: SPO22
Organism: Saccharomyces cerevisiae
Length: 975 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPO22.

Description E-value Query
Range
Subject
Range
gi|21622377 - gi|21622377|emb|CAD37031.1| conserved hypothetical protein [Neurospora crassa]
836.0 [0..74] [955..75]

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Predicted Domain #1
Region A:
Residues: [1-220]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDHNVNSTF RKTLVELCET ATWITSQVYA AKNLEKNDLI TVDNKISALY PIAEKYDRSF  60
   61 RTTTVILDEE LILKLENAAS SLWNSLTIAM KAEKASDKYF NEVFCKCKIF ATKLLSIHEA 120
  121 LFRTNTNLLR NFKCYISSFK SASEYRFDDL ITNTQQHSEK YLQIINENVE SFSNEEKTEF 180
  181 KKLTFEFYLV NFQLYLSEND LDTANIYTAK VNITDNSKYM 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [221-603]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DADLLIELCR MIYNSTVMLK EINNPETQLV DVNIISFLKD VEKYLELPVE NLKSHTDYSN  60
   61 LKYSVLIFMA NCLVEGHPQA SELEQCDHYL SLLQNEYPNK VDPFILAINL TKRRNIVNPA 120
  121 ETIEEILMRM IMSVDVISNF QAVIASINDL SKMNTKFSIV CLDYLLINKL NSKNDSKFLG 180
  181 KAICSRFLIT TQSKTMNDSE IAESLENFST QMERIVSEPL TKHAISCIIT LLWNTGKKLE 240
  241 KMEKYVVSIR FYKLALKDII SQNYSDRGKI QRALQVVYNK IEDYSNTVRV YQDMDEVDRQ 300
  301 SPLCQLLMLQ SFLADDKTEE ALTCLQKIKS SEDEKSTDAL ILAVAECKRK TDLSVQGLLM 360
  361 IFDKLQSKSN SQTISSTSSS QTL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 17.39794
Match: 1w3bA
Description: The superhelical TPR domain of O-linked GlcNAc transferase reveals structural similarities to importin alpha.
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.57186536498101 bayes_pls_golite062009
protein binding 1.83529176977066 bayes_pls_golite062009
transcription factor binding 0.350910388473439 bayes_pls_golite062009
transcription cofactor activity 0.1539868026804 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [604-815]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SILRYTLQMI VKVSEEEPLE TFINYLPTVQ KLLQKAVEFL KTVKLLNQLP PDVEKEAIYQ  60
   61 QSVAVNEIEW FASFSYNVAV KCLVDQSCES ISEFPQYCIQ FIDLIPVQDF TFPKMYHFTY 120
  121 WRFKATILQL IIAKEKAKQD QHQKDWDIYE KSEELVNSIN VMKKSSEFKD GSSLEDRNTL 180
  181 HECFLEALTI HLESALMMPD QTRILDILKK TE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [816-975]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LYQDSRVDAL LIDISSNMED LPKGVLIEIL ETVLKRNMGP EVKERELCSW LRILLENAIN  60
   61 LNHEVELRIL DRVLKILNIN QSSLQDTDGV LQTELETIAT YCWNIGVNYI IKDNKSNGIV 120
  121 WCKHSMGFAN MVNEGLQEQL YSLWESLASS ANIDINSIAK 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle