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Protein Overview: FCERB_MOUSE

General Information:
Name(s) found: FCERB_MOUSE [Swiss-Prot]
Description(s) found:
Found 36 descriptions.
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  • High affinity immunoglobulin epsilon receptor subunit beta OS=Mus musculus GN=Ms4a2 PE=1 SV=1 [Swiss-Prot]
    • Organism: Mus musculus
    Length: 235 amino acids

    Gene Ontology:
    Cellular Component: integral to plasma membrane [UNKNOWN][IDA]
    endosome [UNKNOWN]
    membrane [IEA]
    membrane raft [UNKNOWN][TAS]
    integral to membrane [IEA]
    external side of plasma membrane [IDA]
    Fc-epsilon receptor I complex [IDA]
    Biological Process: cytokine secretion [UNKNOWN]
    regulation of release of sequestered calcium ion into cytosol [UNKNOWN]
    positive regulation of mast cell degranulation [UNKNOWN]
    inflammatory response [UNKNOWN]
    signal transduction [UNKNOWN][IDA]
    activation of phospholipase C activity [UNKNOWN]
    cell surface receptor linked signaling pathway [IDA]
    activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway [UNKNOWN]
    Molecular Function: protein kinase binding [UNKNOWN]
    IgE binding [IDA]
    phosphoprotein binding [UNKNOWN]
    receptor activity [IEA]
    SH2 domain binding [UNKNOWN]
    IgE receptor activity [UNKNOWN]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDTENRSRAD LALPNPQESS SAPDIELLEA SPAKAAPPKQ TWRTFLKKEL EFLGATQILV  60
   61 GLICLCFGTI VCSVLYVSDF DEEVLLLYKL GYPFWGAVLF VLSGFLSIIS ERKNTLYLVR 120
  121 GSLGANIVSS IAAGTGIAML ILNLTNNFAY MNNCKNVTED DGCFVASFTT ELVLMMLFLT 180
  181 ILAFCSAVLF TIYRIGQELE SKKVPDDRLY EELNVYSPIY SELEDKGETS SPVDS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run RPA135 No Comments Schneider, DA, et al. (2006)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..235] FFAS03 0.951 Crystal structure of Nitrate Reductase A, NarGHI, from Escherichia coli

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  1.54554694821029 bayes_pls_golite062009
  • catalytic activity
    		•  0.43294393089871 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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