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Any process that modulates the frequency, rate, or extent of mast cell degranulation. The regulated exocytosis of secretory granules containing preformed mediators such as histamine, serotonin, and neutral proteases by a mast cell. Any process that modulates the frequency, rate, or extent of myeloid leukocyte mediated immunity. Any process involved in the carrying out of an immune response by a mast cell. The change in morphology and behavior of a mast cell resulting from exposure to a cytokine, chemokine, soluble factor, or to (at least in mammals) an antigen which the mast cell has specifically bound via IgE bound to Fc-epsilonRI receptors, leading to the initiation or perpetuation of an immune response. Any process that activates or increases the frequency, rate or extent of leukocyte degranulation. Any process that modulates the frequency, rate, or extent of leukocyte degranulation. Any process that activates or increases the frequency, rate, or extent of mast cell activation during an immune response. Any process that modulates the frequency, rate, or extent of mast cell activation during an immune response. Any process that activates or increases the frequency, rate, or extent of mast cell activation. The regulated exocytosis of secretory granules by a leukocyte. Any process that activates or increases the frequency, rate, or extent of an immune effector process. Any process that activates or increases the frequency, rate or extent of mast cell degranulation. Any process that activates or increases the frequency, rate or extent of exocytosis.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: positive regulation of mast cell degranulation
Acc: GO:0043306
Aspect: Biological Process
Desc: Any process that activates or increases the frequency, rate or extent of mast cell degranulation.
Synonyms:
  • activation of mast cell degranulation
  • stimulation of mast cell degranulation
  • positive regulation of mast cell granule exocytosis
  • up-regulation of mast cell degranulation
  • up regulation of mast cell degranulation
  • upregulation of mast cell degranulation
Proteins in PDR annotated with:
   This term: 19 [Search]
   Term or descendants: 19 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0043306 - positive regulation of mast cell degranulation (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle