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Protein Overview: JIP5

General Information:
Name(s) found: JIP5 / YPR169W [SGD]
Description(s) found:
Found 16 descriptions.
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  • Essential protein required for biogenesis of the large ribosomal subunit; interacts with proteins involved in RNA processing, ribosome biogenesis, ubiquitination and demethylation; similar to WDR55, a human WD repeat protein [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 514 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed articleLink to PubMed article]
    nucleolus [IDALink to PubMed articleLink to PubMed article]
    Biological Process: protein monoubiquitination [IPILink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASSPQLEEE AAGKLETIHA SAMAKSKKKT DVVDSTNLPI LELLSLKAPI FQSLLHPELP  60
   61 IIITGFGTGH IVCHRYDPAK LQSHLDRRRR IDTATTGKDA KKGVCPWIRL DIDLETGDLK 120
  121 FVDIEEQQQQ KQTGKDEDLG VKTLWKTKRH KGSVRAMCFD SKGDNIFSVG SDNVLKKANT 180
  181 MTGKVVKKVN LSSLFNSEEK KNDKFTKLCA SQTHPFILIG DESGNIHVIN SENLALSNSI 240
  241 RSIHFGDSIN DIFHFDKRSA YKFISLGQTT LAYFDVRDKD AKPNVAGNED GKILISDDQE 300
  301 DEVLCGCFVD PEVADTLLCG MGEGIVTVWK PNKNDLEDQM SRIKISKDES IDCIVPTLQD 360
  361 DNCVWCGCSN GNIYKVNAKL GKVVEIRNHS ELDEVSFVDL DFEYRVVSGG LENIKIWELS 420
  421 SDDVEENASV ESDSDEPLSH SDEDLSDDTS SDDETTLVGL SKEELLDELD KDLKEDHQEE 480
  481 KESNSKSVKK RKIMKENNKK KDLYEHGIKK FDDL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run JIP5 No Comments Hazbun TR, et al. (2003)
    View Run CEP3 sample cbf3 from feb 2005 Sandall S, et all (2006)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data JIP5 and SPC42 Hazbun TR, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..380] PSI-BLAST 18.0 Arp2/3 complex 41 kDa subunit ARPC1
    2 View Details [381..514] PSI-BLAST 76.69897 beta1-subunit of the signal-transducing G protein heterotrimer


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle