Protein Overview: TFP3

General Information:
Name(s) found:	TFP3 / YPL234C [SGD]
Description(s) found: Found 34 descriptions. SHOW ALL	Vacuolar ATPase V0 domain subunit c', involved in proton transport activity; hydrophobic integral membrane protein (proteolipid) containing four transmembrane segments; N and C termini are in the vacuolar lumen [SGD]
Organism:	Saccharomyces cerevisiae
Length:	164 amino acids
Gene Ontology:
Cellular Component:	vacuolar proton-transporting V-type ATPase, V0 domain [TAS ] integral to membrane [IDA]
Biological Process:	vacuolar acidification [TAS ]
Molecular Function:	proton-transporting ATPase activity, rotational mechanism [TAS ]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTQLASNIY APLYAPFFGF AGCAAAMVLS CLGAAIGTAK SGIGIAGIGT FKPELIMKSL  60
   61 IPVVMSGILA IYGLVVAVLI AGNLSPTEDY TLFNGFMHLS CGLCVGFACL SSGYAIGMVG 120
  121 DVGVRKYMHQ PRLFVGIVLI LIFSEVLGLY GMIVALILNT RGSE

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	(MIPS) Mewes HW, et al. (2004)		CUP5 PPA1 STV1 TFP1 TFP3 VMA10 VMA13 VMA2 VMA4 VMA5 VMA6 VMA7 VMA8 VPH1
View Details	Qiu et al. (2008)		CUP5 PPA1 STV1 TFP1 TFP3 VMA10 VMA13 VMA2 VMA4 VMA5 VMA6 VMA7 VMA8 VMA9 VPH1

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	PUF3	TFP3	1	Unpublished Fields Lab Data
View Screen	PSF3	TFP3	1	Hazbun TR, et al. (2003)

Microscopy / Localization Data

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	PROTEIN(S)	PUBLICATION
View Data	TFP3	Huh WK, et al. (2003)

Protein Structure Data

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Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..85]	Pfam	12.086186	ATP synthase subunit C No confident structure predictions are available.
2	View Details	[86..164]	Pfam	23.568636	ATP synthase subunit C No confident structure predictions are available.

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

[View Details]

Source: Reynolds et al. 2008. Manuscript submitted

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2