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Protein Overview: MSY1

General Information:
Name(s) found: MSY1 / YPL097W [SGD]
Description(s) found:
Found 24 descriptions.
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  • Mitochondrial tyrosyl-tRNA synthetase [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 492 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [IDALink to PubMed articleLink to PubMed article][TASLink to PubMed article]
    Biological Process: tyrosyl-tRNA aminoacylation [TASLink to PubMed article]
    Molecular Function: tyrosine-tRNA ligase activity [TASLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLELRSCSNL VNSSRRLVPL VTYSGLSAIT LPKSRFYSQP SALEVQGTSD SRSDNILDEL  60
   61 KQRGLVSQVS QPESFLRTKL NGNDKIKLYC GVDPTAQSLH LGNLVPLMVL LHFYVKGHDI 120
  121 VTVIGGATGK VGDPSGRKTE RDVMENDIRQ SNVASISQQL QRFFKNGLEY YRNRCALTED 180
  181 VPSGKYTPRN NFNWWKDIKM LDFLADFGRH IRVQSMLARD SISSRLQTKN GLGFNEFTYQ 240
  241 VLQAYDFYHL YKEENVTIQV GGNDQWGNIT AGIDLINRIQ PIKNKGLPFG ITVPLLTTAT 300
  301 GEKFGKSAGN AVFIDPSINT AYDVYQFFYN TLDADVPKFL KIFTFLNSSE IKKIVETHIK 360
  361 SPSLRYGQTL LAKEVTDMLY GVGSGSDSEA LSNIIFGRYD GTLSAAKLVD LCKKARILQY 420
  421 ADREIDLIKL ICKLVNCSVS EARRKLSQGS VYLHHSKSKV NENISNLAPF LIDDRVLILR 480
  481 IGKQKCFIIE MR

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Qiu et al. (2008) DIA4 MSY1

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #24 Asynchronous Prep3-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)
    View Run MLP2 #26 Asynchronous Prep4-TiO2 Phosphopeptide enriched, Steps1-2 Keck JM, et al. (2011)
    View Run MLP2 #32 Asynchronous Prep-No Phosphopeptide enrichment Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen CLN3 MSY1 2 Unpublished Fields Lab Data
    View Screen PPT1 MSY1 1 Unpublished Fields Lab Data
    View Screen RCY1 MSY1 1 Unpublished Fields Lab Data
    View Screen LOS1 MSY1 1 Unpublished Fields Lab Data
    View Screen APC5 MSY1 1 Unpublished Fields Lab Data

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data MSY1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..297] PSI-BLAST 870.0 Tyrosyl-tRNA synthetase (TyrRS)
    2 View Details [298..492] PSI-BLAST 870.0 Tyrosyl-tRNA synthetase (TyrRS)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • ligase activity, forming carbon-oxygen bonds
    		•  7.16276509815667 bayes_pls_golite062009
  • ligase activity, forming aminoacyl-tRNA and related compounds
    		•  7.16276509815667 bayes_pls_golite062009
  • aminoacyl-tRNA ligase activity
    		•  7.13957775963187 bayes_pls_golite062009
  • tyrosine-tRNA ligase activity
    		•  6.18775771640881 bayes_pls_golite062009
  • ligase activity
    		•  6.11211476973434 bayes_pls_golite062009
  • glutamate-tRNA ligase activity
    		•  2.63681738794687 bayes_pls_golite062009
  • methionine-tRNA ligase activity
    		•  2.56893064485672 bayes_pls_golite062009
  • catalytic activity
    		•  2.37674226834122 bayes_pls_golite062009
  • arginine-tRNA ligase activity
    		•  1.50161401062914 bayes_pls_golite062009
  • tryptophan-tRNA ligase activity
    		•  1.14187887833901 bayes_pls_golite062009
  • cysteine-tRNA ligase activity
    		•  0.844943947059557 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.625793556381714 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.449504767632354 bayes_pls_golite062009
  • nucleotidyltransferase activity
    		•  0.2293846471193 bayes_pls_golite062009
  • glutamine-tRNA ligase activity
    		•  0.118292082006187 bayes_pls_golite062009
  • binding
    		•  0.090743795600025 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.74

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle