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Protein Overview: DGA1

General Information:
Name(s) found: DGA1 / YOR245C [SGD]
Description(s) found:
Found 26 descriptions.
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  • Diacylglycerol acyltransferase, catalyzes the terminal step of triacylglycerol (TAG) formation, acylates diacylglycerol using acyl-CoA as an acyl donor, localized to lipid particles [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 418 amino acids

    Gene Ontology:
    Cellular Component: lipid particle [IDALink to PubMed article]
    Biological Process: lipid storage [IMPLink to PubMed article]
    triglyceride biosynthetic process [IDALink to PubMed article][IMPLink to PubMed article]
    Molecular Function: diacylglycerol O-acyltransferase activity [IMPLink to PubMed article][ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSGTFNDIRR RKKEEGSPTA GITERHENKS LSSIDKREQT LKPQLESCCP LATPFERRLQ  60
   61 TLAVAWHTSS FVLFSIFTLF AISTPALWVL AIPYMIYFFF DRSPATGEVV NRYSLRFRSL 120
  121 PIWKWYCDYF PISLIKTVNL KPTFTLSKNK RVNEKNYKIR LWPTKYSINL KSNSTIDYRN 180
  181 QECTGPTYLF GYHPHGIGAL GAFGAFATEG CNYSKIFPGI PISLMTLVTQ FHIPLYRDYL 240
  241 LALGISSVSR KNALRTLSKN QSICIVVGGA RESLLSSTNG TQLILNKRKG FIKLAIQTGN 300
  301 INLVPVFAFG EVDCYNVLST KKDSVLGKMQ LWFKENFGFT IPIFYARGLF NYDFGLLPFR 360
  361 APINVVVGRP IYVEKKITNP PDDVVNHFHD LYIAELKRLY YENREKYGVP DAELKIVG

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Qiu et al. (2008) DGA1 EHT1 SLC1 TGL5

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run RPA135 No Comments Schneider, DA, et al. (2006)
    View Run MLP2 #29 Asynchronous Prep5-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen SEC17 DGA1 2 Unpublished Fields Lab Data
    View Screen YIF1 DGA1 2 Unpublished Fields Lab Data
    View Screen UTP9 DGA1 1 Unpublished Fields Lab Data
    View Screen YPT6 DGA1 1 Unpublished Fields Lab Data

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data DGA1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..144] deduced N/A No confident structure predictions are available.
    2 View Details [145..418] MSA 66.172997 View MSA. No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle