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Protein Overview: ATX2

General Information:
Name(s) found: ATX2 / YOR079C [SGD]
Description(s) found:
Found 29 descriptions.
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  • Golgi membrane protein involved in manganese homeostasis; overproduction suppresses the sod1 (copper, zinc superoxide dismutase) null mutation [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 313 amino acids

    Gene Ontology:
    Cellular Component: Golgi membrane [IDALink to PubMed article]
    Biological Process: cellular manganese ion homeostasis [IGILink to PubMed article][IMPLink to PubMed article]
    Molecular Function: manganese ion transmembrane transporter activity [IGILink to PubMed article][IMPLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKFLGVILLA SFLLIATFLI GLIPLYYIDK QKSSIVTNQE GADSISDFTT NADTQTINDD  60
   61 VSSYRVKIAV LSQFGIGMLL GTSFMLVIPE GIKACVEHDG NVGVNLLIGF LGVYVLDRLV 120
  121 TLWVSRKQTV YTHDAVKFQS WKDIINHPRQ IWMNLIQNNV VFALFIHGLS DGIALGTTTN 180
  181 NDSLLIVVLI AIVIHKIPAV LSLTSLMVSR QNLMKWEVIC NVFLFASSTP IGYIVLSLLN 240
  241 LSHSPTMDWI SGNLLLMSGG SLLYASFTAF VGGDSHDHDL SVEQEVVLPH DESVYVLIGV 300
  301 CIPLVISYCI SEE

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Qiu et al. (2008) ATX2 CCC1 GEF1

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run CEP3 sample cbf3 from feb 2005 Sandall S, et all (2006)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen YNL146W ATX2 2 Unpublished Fields Lab Data
    View Screen CUS1 ATX2 1 Unpublished Fields Lab Data

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..128] MSA 4.122994 View MSA. No confident structure predictions are available.
    2 View Details [129..313] Pfam 42.008774 ZIP Zinc transporter No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
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