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Protein Overview: NGL1

General Information:
Name(s) found: NGL1 / YOL042W [SGD]
Description(s) found:
Found 33 descriptions.
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  • Putative endonuclease, has a domain similar to a magnesium-dependent endonuclease motif in mRNA deadenylase Ccr4p; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 363 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [IDALink to PubMed articleLink to PubMed article]
    Biological Process: biological_process [ND]
    Molecular Function: endonuclease activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFTRRFIPVV QSTKQNIGKY VRKDARFTLL TYNMLSPSYM WPQVYTYVAE PYKNWSYRHR  60
   61 LLEKELLNTF KADIMCLQEM TARDYEDYWH DSIGVDVNYG SKFISKTPPK YWKKPVKDMD 120
  121 GVSIFYNLAK FDFISSSGIY LNQLLNVFNQ RELKYLYNKK VTLTDGASNV IGEDSLLDVL 180
  181 KGKNQVCLFV SLRHKETGTI FVVLNTHLYW KYDEVKLTQC MIIMRELSKI IKQLLPGDVK 240
  241 GQERVKILFT GDLNSTRDSL VVNFLQGQIV SHGDLNLINP MRPYLDRCVY DDIPKDYFVH 300
  301 TCYSGKLKGI FDYVWYHDSD FLLTKILTGN EVSDELLASN QLGLPNENHP SDHIPLLTEF 360
  361 KIL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data NGL1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..363] ORFEUS 13.06 DNA repair endonuclease Hap1

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • hydrolase activity
    		•  3.03637986118891 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  2.64138912616286 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.38142407142222 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.36300991054709 bayes_pls_golite062009
  • DNA binding
    		•  2.34848945028683 bayes_pls_golite062009
  • binding
    		•  1.77207262408714 bayes_pls_golite062009
  • catalytic activity
    		•  1.63030570728465 bayes_pls_golite062009
  • nuclease activity
    		•  1.43406183661088 bayes_pls_golite062009
  • transcription coactivator activity
    		•  1.3192080792879 bayes_pls_golite062009
  • deoxyribonuclease activity
    		•  1.2263976316786 bayes_pls_golite062009
  • exonuclease activity
    		•  1.0469071871605 bayes_pls_golite062009
  • oxidoreductase activity
    		•  1.01237142327007 bayes_pls_golite062009
  • ribonuclease activity
    		•  0.921398762372674 bayes_pls_golite062009
  • exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
    		•  0.816802516530232 bayes_pls_golite062009
  • transcription activator activity
    		•  0.794530147502372 bayes_pls_golite062009
  • transcription factor binding
    		•  0.676190329566283 bayes_pls_golite062009
  • protein binding
    		•  0.477100720412367 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.456888438009074 bayes_pls_golite062009
  • exodeoxyribonuclease activity, producing 5'-phosphomonoesters
    		•  0.268550639537333 bayes_pls_golite062009
  • exodeoxyribonuclease activity
    		•  0.260804033000249 bayes_pls_golite062009
  • endonuclease activity
    		•  0.122198690326292 bayes_pls_golite062009


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle