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Protein Overview: COQ2

General Information:
Name(s) found: COQ2 / YNR041C [SGD]
Description(s) found:
Found 27 descriptions.
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  • Para hydroxybenzoate: polyprenyl transferase, catalyzes the second step in ubiquinone (coenzyme Q) biosynthesis [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 372 amino acids

    Gene Ontology:
    Cellular Component: mitochondrial membrane [IDALink to PubMed article]
    mitochondrion [IDALink to PubMed articleLink to PubMed articleLink to PubMed article]
    microsome [IDALink to PubMed article]
    Biological Process: ubiquinone biosynthetic process [IGILink to PubMed article][IMPLink to PubMed article]
    Molecular Function: 4-hydroxybenzoate octaprenyltransferase activity [IGILink to PubMed article][IMPLink to PubMed article][ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFIWQRKSIL LGRSILGSGR VTVAGIIGSS RKRYTSSSSS SSSPSSKESA PVFTSKELEV  60
   61 ARKERLDGLG PFVSRLPKKW IPYAELMRLE KPVGTWLLYL PCSWSILMGA MMQGATLSAT 120
  121 AGMLGIFGVG ALVMRGAGCT INDFLDRKLD QRVIRSVERP IASGRVSPRR ALVFLGAQTL 180
  181 VGMGVLSLLP AQCWWLGLAS LPIVFTYPLF KRFTYYPQAA LSACFNWGAL LGFPAMGVMS 240
  241 WPTMIPLYLS SYLWCMTYDT IYAHQDKKFD IKAGIKSTAL AWGPRTKSIM KAMSASQIAL 300
  301 LAVAGLNSGL LWGPGFIGGL GVFAYRLFSM IKKVDLDNPK NCWKYFNANI NTGLYFTYAL 360
  361 AVDYILRLFG FL

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Qiu et al. (2008) COQ2 FMN1

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #03 Alpha Factor Prep1-TiO2 Flowthrough Keck JM, et al. (2011)
    View Run MLP2 #13 Mitotic Prep2-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data COQ2 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..94] deduced N/A No confident structure predictions are available.
    2 View Details [95..372] Pfam 75.508638 UbiA prenyltransferase family No confident structure predictions are available.
    3 View Details [266..372] MSA 1.748994 View MSA. No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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