YRC Public Data Repository - Protein Structure Prediction

Protein:	COQ2
Organism:	Saccharomyces cerevisiae
Length:	372 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for COQ2.

Description	E-value	Query Range	Subject Range
COQ2 - Para hydroxybenzoate: polyprenyl transferase, catalyzes the second step in ubiquinone (coenzyme Q) b... COQ2_YEAST - 4-hydroxybenzoate polyprenyltransferase, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 2045...	7.0E-64	[1..372]	[1..372]
coq-2 - 4-hydroxybenzoate octaprenyltransferase status:Confirmed UniProt:Q8I7J4 protein_id:AAW88395.1	3.0E-61	[27..367]	[6..345]
COQ2_ARATH - 4-hydroxybenzoate polyprenyltransferase, mitochondrial OS=Arabidopsis thaliana GN=PPT1 PE=2 SV=1	2.0E-60	[34..363]	[80..403]
Coq2-PA - The gene Coenzyme Q biosynthesis protein 2 is referred to in FlyBase by the symbol Dmel\Coq2 (CG9613... gi\|220949886 - gi\|220949886\|gb\|ACL87486.1\| Coq2-PA [synthetic construct]	4.0E-58	[30..367]	[30..360]
COQ2 - coenzyme Q2 homolog, prenyltransferase (yeast) gi\|157929092, gi... - gi\|157929092\|gb\|ABW03831.1\| coenzyme Q2 homolog, prenyltransferase (yeast) [synthetic construct], gi...	6.0E-56	[45..366]	[32..353]
gi\|17987801, gi\|... - gi\|17987801\|ref\|NP_540435.1\| prenyltransferase [Brucella melitensis 16M], gi\|17983526\|gb\|AAL52699.1\|... gi\|25331786 - pir\|\|AH3441 4-hydroxybenzoate octaprenyltransferase (EC 2.5.1.-) [imported] - Brucella melitensis (s...	3.0E-55	[53..366]	[8..326]
gi\|25331762 - pir\|\|C87673 4-hydroxybenzoate octaprenyltransferase [imported] - Caulobacter crescentus gi\|16127651, gi\|... - gi\|16127651\|ref\|NP_422215.1\| 4-hydroxybenzoate octaprenyltransferase [Caulobacter crescentus CB15], ... gi\|220965643, gi... - gi\|221236470\|ref\|YP_002518907.1\| 4-hydroxybenzoate polyprenyltransferase [Caulobacter crescentus NA1...	2.0E-54	[50..371]	[10..328]
coq2 - para-hydroxybenzoate--polyprenyltransferaseCoq2 gi\|19114131 - gi\|19114131\|ref\|NP_593219.1\| hypothetical protein SPAC56F8.04c [Schizosaccharomyces pombe 972h-]	1.0E-52	[33..369]	[11..354]
gi\|13476189, gi\|... - gi\|14026949\|dbj\|BAB53545.1\| 4-hydroxybenzoate-octaprenyl transferase [Mesorhizobium loti MAFF303099]...	7.0E-52	[54..366]	[3..320]
gi\|15836673, gi\|... - gi\|9104838\|gb\|AAF82881.1\|AE003860_8 hydroxybenzoate octaprenyltransferase [Xylella fastidiosa 9a5c],... gi\|11361041 - pir\|\|H82852 hydroxybenzoate octaprenyltransferase XF0068 [imported] - Xylella fastidiosa (strain 9a5...	1.0E-51	[43..363]	[25..330]

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Predicted Domain #1

Region A:
Residues: [1-94]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFIWQRKSIL LGRSILGSGR VTVAGIIGSS RKRYTSSSSS SSSPSSKESA PVFTSKELEV  60
   61 ARKERLDGLG PFVSRLPKKW IPYAELMRLE KPVG

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [95-372]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TWLLYLPCSW SILMGAMMQG ATLSATAGML GIFGVGALVM RGAGCTINDF LDRKLDQRVI  60
   61 RSVERPIASG RVSPRRALVF LGAQTLVGMG VLSLLPAQCW WLGLASLPIV FTYPLFKRFT 120
  121 YYPQAALSAC FNWGALLGFP AMGVMSWPTM IPLYLSSYLW CMTYDTIYAH QDKKFDIKAG 180
  181 IKSTALAWGP RTKSIMKAMS ASQIALLAVA GLNSGLLWGP GFIGGLGVFA YRLFSMIKKV 240
  241 DLDNPKNCWK YFNANINTGL YFTYALAVDY ILRLFGFL

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	75.508638
Match:	PF01040
Description:	UbiA prenyltransferase family

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [266-372]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DKKFDIKAGI KSTALAWGPR TKSIMKAMSA SQIALLAVAG LNSGLLWGPG FIGGLGVFAY  60
   61 RLFSMIKKVD LDNPKNCWKY FNANINTGLY FTYALAVDYI LRLFGFL

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits