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Protein Overview: PGM3

General Information:
Name(s) found: PGM3 / YMR278W [SGD]
Description(s) found:
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  • gi|825544|emb|CAA89776.1| unknown [Saccharomyces cerevisiae] [NCBI NR]
  • gi|6323934|ref|NP_014005.1| Phosphoglucomutase, catalyzes interconversion of glucose-1-phosphate and glucose-6-phospate; transcription induced in response to stress; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; no [NCBI NR]
  • gi|2499517|sp|Q03262.1|PGM3_YEAST RecName: Full=Phosphoglucomutase YMR278W; Short=PGM; AltName: Full=Glucose phosphomutase [NCBI NR]
  • pir||S54585 hypothetical protein YMR278w - yeast (Saccharomyces cerevisiae) [NCBI NR]
  • Uncharacterized protein YMR278W - Saccharomyces cerevisiae (Baker's yeast) [Swiss-Prot]
  • Phosphoglucomutase YMR278W OS=Saccharomyces cerevisiae GN=YMR278W PE=1 SV=1 [Swiss-Prot]
  • Putative phosphomannomutases [mips]
  • Phosphoglucomutase, catalyzes interconversion of glucose-1-phosphate and glucose-6-phospate; transcription induced in response to stress; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; non-essential [SGD]
  • YMR278W, Chr XIII from 822763-824631 [yeast_orfs2]
  • Chr XIII from 822763-824631 [yeastorf3.fasta]
  • (Q03262) Hypothetical 71.1 kDa protein in DSK2-CAT8 intergenic region [4932.FASTACCERV.txt]
  • YMR278W SGDID:S0004891, Chr XIII from 822762-824630, Uncharacterized ORF [yeastflysequest.fasta]
  • Ymr278wp [Saccharomyces cerevisiae]gi|825544|emb|CAA89776.1| unknown [Saccharomyces cerevisiae]gi|2499517|sp|Q03262|YM8L_YEAST Hypothetical 71.1 kDa protein in DSK2-CAT8 intergenic regiongi|1078534|pir||S54585 hypothetical protein YMR278w - yeast (Sacc [nrdb_11152004_Chlamydomonas]
  • YMR278W SGDID:S000004891, Chr XIII from 822762-824630, Uncharacterized ORF, "Hypothetical protein" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta]
  • YMR278W SGDID:S000004891, Chr XIII from 822762-824630, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; YMR278W is not an essential gene" [yeast-contam.fasta]
  • PGM3 SGDID:S000004891, Chr XIII from 822762-824630, Verified ORF, "Phosphoglucomutase, catalyzes interconversion of glucose-1-phosphate and glucose-6-phospate; transcription induced in response to stress; green fluorescent protein (GFP)-fusion protein loc [SGD_S-cerevisiae_na_08-19-2008_con_reversed.fasta]
  • Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; YMR278W is not an essential gene; Ymr278wp [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • Uncharacterized protein YMR278W [nr-271106-contam.fasta]
  • unknown [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • PGM3 SGDID:S000004891, Chr XIII from 822762-824630, Verified ORF, "Phosphoglucomutase, catalyzes interconversion of glucose-1-phosphate and glucose-6-phospate; transcription induced in response to stress; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; non-essential" [yeast-bovrabprots.fasta]
  • [chemostatdb.fasta]
  • Phosphoglucomutase-3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PGM3 PE=1 SV=1 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta]
  • PGM3 SGDID:S000004891, Chr XIII from 822763-824631, Genome Release 64-1-1, Verified ORF, "Phosphoglucomutase, catalyzes interconversion of glucose-1-phosphate and glucose-6-phospate; transcription induced in response to stress; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; non-essential" [yeast-030211-contam.fasta]
  • PRM15 SGDID:S000004891, Chr XIII from 822763-824631, Genome Release 64-2-1, Verified ORF, "Phosphoribomutase; catalyzes interconversion of ribose-1-phosphate and ribose-5-phosphate; has some phosphoglucomutase activity but primary activity in vivo is phosphoribomutase; contributes to ribose recycling in the pentose phosphate pathway; transcription induced in response to stress; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; non-essential" [20141208_orf_trans.fasta]
  • YMR278W SGDID:S000004891, Chr XIII from 822763-824631, Genome Release 64-1-1, Verified ORF, "Phosphoglucomutase, catalyzes interconversion of glucose-1-phosphate and glucose-6-phospate; transcription induced in response to stress; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; non-essential" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
  • Phosphoribomutase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PRM15 PE=1 SV=1 [uniprot_sprot.fasta.20160308]
    • Organism: Saccharomyces cerevisiae
    Length: 622 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytoplasm [IDALink to PubMed article]
    Biological Process: biological_process [ND]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLQGILETVP SDLKDPISLW FKQDRNPKTI EEVTALCKKS DWNELHKRFD SRIQFGTAGL  60
   61 RSQMQAGFSR MNTLVVIQAS QGLATYVRQQ FPDNLVAVVG HDHRFHSKEF ARATAAAFLL 120
  121 KGFKVHYLNP DHEFVHTPLV PFAVDKLKAS VGVMITASHN PKMDNGYKVY YSNGCQIIPP 180
  181 HDHAISDSID ANLEPWANVW DFDDVLNKAL KQGKLMYSRE EMLKLYLEEV SKNLVEINPL 240
  241 KLEVKAKPWF VYTPMHGVGF DIFSTIVKKT LCLVEGKDYL CVPEQQNPDP SFPTVGFPNP 300
  301 EEKGALDIGI NLAEKHDIDL LVANDPDADR FSVAVKDMQS GEWRQLTGNE IGFLFAFYEY 360
  361 QKYKSMDKEF QHVHPLAMLN STVSSQMIKK MAEIEGFHYE DTLTGFKWIG NRAILLEKKG 420
  421 YYVPFGFEEA IGYMFPAMEH DKDGISASIV FLQAYCKWKI DHNLDPLNVL ENGFKKYGVF 480
  481 KEYNGYYVVP NPTVTKDIFD YIRNVYTPEG ASYPSSIGEE IEVLYYRDLT TGYQSDTINH 540
  541 KPTLPVDPTS QMITVSARPS NGSENEHIRF TIRGSGTEPK LKVYIEACAN EEQRASFLAK 600
  601 LTWNVLRREW FRPDEMNIVT KF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run RPA135 No Comments Schneider, DA, et al. (2006)
    View Run MLP2 #32 Asynchronous Prep-No Phosphopeptide enrichment Keck JM, et al. (2011)
    View Run MLP2 #29 Asynchronous Prep5-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen YCK1 PGM3 1 Unpublished Fields Lab Data
    View Screen PUF3 PGM3 1 Unpublished Fields Lab Data

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data PGM3 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..224] PSI-BLAST 155.228787 Phosphoglucomutase
    2 View Details [225..345]
    [437..468]    		 PSI-BLAST 155.228787 Phosphoglucomutase
    3 View Details [346..436]
    [469..479]
    [538..549]    		 PSI-BLAST 155.228787 Phosphoglucomutase
    4 View Details [480..537]
    [550..622]    		 PSI-BLAST 155.228787 Phosphoglucomutase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  1.61980820714401 bayes_pls_golite062009
  • intramolecular transferase activity, phosphotransferases
    		•  0.9938893438261 bayes_pls_golite062009
  • phosphomannomutase activity
    		•  0.96914970670646 bayes_pls_golite062009
  • catalytic activity
    		•  0.792640318995558 bayes_pls_golite062009
  • isomerase activity
    		•  0.340395019264179 bayes_pls_golite062009
  • phosphoglucomutase activity
    		•  0.268745464529951 bayes_pls_golite062009
  • protein binding
    		•  0.259532204752794 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle