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Protein Overview: ERG2

General Information:
Name(s) found: ERG2 / YMR202W [SGD]
Description(s) found:
Found 25 descriptions.
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  • C-8 sterol isomerase, catalyzes the isomerization of the delta-8 double bond to the delta-7 position at an intermediate step in ergosterol biosynthesis [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 222 amino acids

    Gene Ontology:
    Cellular Component: endoplasmic reticulum [TAS]
    Biological Process: telomere maintenance [IMPLink to PubMed article]
    ergosterol biosynthetic process [TAS]
    Molecular Function: C-8 sterol isomerase activity [TAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKFFPLLLLI GVVGYIMNVL FTTWLPTNYM FDPKTLNEIC NSVISKHNAA EGLSTEDLLQ  60
   61 DVRDALASHY GDEYINRYVK EEWVFNNAGG AMGQMIILHA SVSEYLILFG TAVGTEGHTG 120
  121 VHFADDYFTI LHGTQIAALP YATEAEVYTP GMTHHLKKGY AKQYSMPGGS FALELAQGWI 180
  181 PCMLPFGFLD TFSSTLDLYT LYRTVYLTAR DMGKNLLQNK KF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run VAM3 Sample: HX14 - mixture in detergent (control). Hao Xu, et al. (2010)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data ERG2 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..222] MSA 2.013958 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • intramolecular oxidoreductase activity
    		•  1.47638758343628 bayes_pls_golite062009
  • binding
    		•  0.608869922150629 bayes_pls_golite062009
  • catalytic activity
    		•  0.403492961582325 bayes_pls_golite062009


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle