Protein Overview: VBA1

General Information:
Name(s) found:	VBA1 / YMR088C [SGD]
Description(s) found: SHOW ONLY BEST	gi\|807971\|emb\|CAA89235.1\| unknown [Saccharomyces cerevisiae] [NCBI NR] gi\|6323735\|ref\|NP_013806.1\| Permease of basic amino acids in the vacuolar membrane; Vba1p [Saccharomyces cerevisiae] [NCBI NR] gi\|2501164\|sp\|Q04301.1\|VBA1_YEAST RecName: Full=Vacuolar basic amino acid transporter 1 [NCBI NR] pir\|\|S54464 probable membrane protein YMR088c - yeast (Saccharomyces cerevisiae) [NCBI NR] (Q04301) Hypothetical transport protein YMR088C [Swiss-Prot] Vacuolar basic amino acid transporter 1 OS=Saccharomyces cerevisiae GN=VBA1 PE=1 SV=1 [Swiss-Prot] VBA1 Permease of basic amino acids in the vacuolar membrane [mips] Permease of basic amino acids in the vacuolar membrane [SGD] YMR088C, Chr XIII from 443413-445101, reverse complement [yeast_orfs2] Chr XIII from 443413-445101, reverse complement [yeastorf3.fasta] Chr XIII from 445101-443413, reverse complement [yeastorf5.fasta] (Q04301) Hypothetical 62.6 kDa protein in ADH3-RCA1 intergenic region [4932.FASTACCERV.txt] YMR088C SGDID:S0004694, Chr XIII from 445101-443413, reverse complement, Uncharacterized ORF [yeastflysequest.fasta] Ymr088cp [Saccharomyces cerevisiae]gi\|807971\|emb\|CAA89235.1\| unknown [Saccharomyces cerevisiae]gi\|1078589\|pir\|\|S54464 probable membrane protein YMR088c - yeast (Saccharomyces cerevisiae)gi\|2501164\|sp\|Q04301\|YMX8_YEAST Hypothetical transport protein YMR [nrdb_11152004_Chlamydomonas] VBA1 SGDID:S000004694, Chr XIII from 445101-443413, reverse complement, Verified ORF, "Permease of basic amino acids in the vacuolar membrane" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta] Permease of basic amino acids in the vacuolar membrane; Vba1p [Saccharomyces cerevisiae] [nr-271106-contam.fasta] Vacuolar basic amino acid transporter 1 [nr-271106-contam.fasta] unknown [Saccharomyces cerevisiae] [nr-271106-contam.fasta] [chemostatdb.fasta] Vacuolar basic amino acid transporter 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=VBA1 PE=1 SV=1 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta] VBA1 SGDID:S000004694, Chr XIII from 445102-443414, Genome Release 64-1-1, reverse complement, Verified ORF, "Permease of basic amino acids in the vacuolar membrane" [yeast-030211-contam.fasta] VBA1 SGDID:S000004694, Chr XIII from 445102-443414, Genome Release 64-2-1, reverse complement, Verified ORF, "Permease of basic amino acids in the vacuolar membrane" [20141208_orf_trans.fasta] YMR088C SGDID:S000004694, Chr XIII from 445102-443414, Genome Release 64-1-1, reverse complement, Verified ORF, "Permease of basic amino acids in the vacuolar membrane" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
Organism:	Saccharomyces cerevisiae
Length:	562 amino acids
Gene Ontology:
Cellular Component:	fungal-type vacuole membrane [IDA]
Biological Process:	epidermal cell fate specification [IDA][IMP] basic amino acid transport [IMP]
Molecular Function:	basic amino acid transmembrane transporter activity [IDA][IMP]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQTLDETSNL LPPPEEAEAP PLEQKFHEYN LALPKFPILF SLWLGSFLSS LDSTIVANIM  60
   61 NRVAEEFSES SKKQWIATSF LLTNTAFQPL YGKLSDITGR KSALLTAQFF FGLGCLLTCF 120
  121 ARNVTEFSIA RAICGIGAGG LNAISSIAVS DICTARERGV YQGYANIVFG FGQLLGAPLG 180
  181 GVFIETIGWR ALFGIQVPVI MLCSVLAIKN INIKLFHVPP MKERYTLKNL SRIDIFGSLS 240
  241 LVATISGVLF LCSSQLNKLY LALFTIGSFI VFILVERYYA TEKILPFELL TRSFCLSSAV 300
  301 TVISSFVVFG EIFRSPIYLQ LLQNISVTKT GLFLIFPSIS VAVGSLVTGW VLRNTKINLA 360
  361 HCAYQIIFGG MIMQLLGLGL GYFLLSHLNP DYTIYDMLES ITFRSNSIWW KLIYVFASVL 420
  421 VSFGYACLLV ATLVSIVFTV EKSQQGTMTG VFYLWRSIGN VLGASLTLVS YENSLSSMLW 480
  481 NYMFKTKRDD EYHFTKKQYY SLINDSSYLR GPNFPTDIFV RILDVYKKAF LISYIPNIAL 540
  541 AAVGIVLSLY LVKHTYKRSS SS

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	Qiu et al. (2008)		AGP2 AVT1 AVT3 AVT4 AVT6 BPT1 DIP5 GAP1 TPO3 UGA4 VBA1 VBA2

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	TRM82	VBA1	2	Unpublished Fields Lab Data
View Screen	LIA1	VBA1	1	Unpublished Fields Lab Data
View Screen	YKU80	VBA1	1	Unpublished Fields Lab Data

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..212] [276..423]	PSI-BLAST	7.522879	No description for 1ja5A_ was found.
2	View Details	[213..275]	PSI-BLAST	7.522879	No description for 1ja5A_ was found.
3	View Details	[424..562]	MSA	2.774997	View MSA. No confident structure predictions are available.

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

[View Details]

Source: Reynolds et al. 2008. Manuscript submitted

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2