YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: UBX2

General Information:
Name(s) found: UBX2 / YML013W [SGD]
Description(s) found:
Found 26 descriptions.
SHOW ALL
  • Protein involved in ER-associated protein degradation; proposed to coordinate the assembly of proteins involved in ERAD; contains a UBX (ubiquitin regulatory X) domain and a ubiquitin-associated (UBA) domain [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 584 amino acids

    Gene Ontology:
    Cellular Component: integral to endoplasmic reticulum membrane [IDALink to PubMed article]
    endoplasmic reticulum [IDALink to PubMed article]
    mitochondrial outer membrane [IDALink to PubMed article]
    Biological Process: proteasomal ubiquitin-dependent protein catabolic process [IMPLink to PubMed article]
    ER-associated protein catabolic process [IMPLink to PubMed article][IPILink to PubMed articleLink to PubMed article]
    protein secretion [IMPLink to PubMed article]
    Molecular Function: protein binding, bridging [IPILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPVVNHEDSE FHLSHTEEDK LNEFQVITNF PPEDLPDVVR LLRNHGWQLE PALSRYFDGE  60
   61 WKGEPDQMGE PTQTSTPMAE TLVPPALGPR PLLFTASLPV VRPLPANFRN DFRTIGLNGR 120
  121 SNTVWSMFES FSYDGNPFLF ILLLIPRIIN RLSATIFTFF CTLLSLHSIS GGGNSGKPKI 180
  181 SKVPKAPTRE THIPLAEILG DTKDKDAFCE LKSFKPDISF NEALRIAKEE FKFMLLILVG 240
  241 DTYDTDTDTV DVNSKLLLEK ILLNKKTLQY LRKIDNDLII YLKCVHELEP WLVARQLGVR 300
  301 NTPEIFLIAN VANKASHSET LPSQRLSILG KLKVNSLNRF LQSLTNVVEK YTPELVVNKT 360
  361 EMHELRMSRE IKKLQEDAYK KSLEMDRIKA IEKEKSLKHA QDLKLNSTAR QLKWLKACID 420
  421 EIQPFETTGK QATLQFRTSS GKRFVKKFPS MTTLYQIYQS IGCHIYLAVY SSDPAEWSNA 480
  481 LQDKIRQLSA DDDMLCFKEG QLETATATTI EELGHIINNE LTSFDLERGK LEFDFELVSP 540
  541 FPKYTVHPNE HMSVDQVPQL WPNGSLLVEA LDEEDEEDEE NEEQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data UBX2 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..95] MSA 2.015997 View MSA. No confident structure predictions are available.
    2 View Details [96..182] deduced N/A No confident structure predictions are available.
    3 View Details [183..351] MSA 1.04498 View MSA. No confident structure predictions are available.
    4 View Details [352..426] deduced N/A No confident structure predictions are available.
    5 View Details [427..518] PSI-BLAST 13.154902 Fas-assosiated factor 1, Faf1
    6 View Details [519..584] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • protein disulfide isomerase activity
    		•  2.05206748531532 bayes_pls_golite062009
  • intramolecular oxidoreductase activity, transposing S-S bonds
    		•  2.05206748531532 bayes_pls_golite062009
  • intramolecular oxidoreductase activity, interconverting keto- and enol-groups
    		•  1.83987272812734 bayes_pls_golite062009
  • intramolecular oxidoreductase activity
    		•  1.5535855642475 bayes_pls_golite062009
  • catalytic activity
    		•  0.672192331361968 bayes_pls_golite062009
  • protein binding
    		•  0.532751276111804 bayes_pls_golite062009
  • hydrolase activity
    		•  0.517269321619613 bayes_pls_golite062009
  • binding
    		•  0.235855919597681 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  0.0866917827040035 bayes_pls_golite062009
    4
    Term Confidence Notes
  • small conjugating protein ligase activity
    		•  6.3238498800949 bayes_pls_golite062009
  • ubiquitin-protein ligase activity
    		•  5.759996473289 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  5.32190918602578 bayes_pls_golite062009
  • ligase activity, forming carbon-nitrogen bonds
    		•  4.23828791893907 bayes_pls_golite062009
  • protein binding
    		•  2.26682390101852 bayes_pls_golite062009
  • ligase activity
    		•  2.25858205355159 bayes_pls_golite062009
  • binding
    		•  1.76448263865625 bayes_pls_golite062009
  • hydrolase activity
    		•  0.614233748923048 bayes_pls_golite062009
    5 No functions predicted.
    6 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.45

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle