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Protein Overview: YLR455W

General Information:
Name(s) found: YLR455W [SGD]
Description(s) found:
Found 28 descriptions.
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  • Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the nucleus; deletion confers sensitivity to 4-(N-(S-glutathionylacetyl)amino) phenylarsenoxide (GSAO) [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 304 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    Biological Process: response to drug [IMPLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTKDIRTGDL VLCKVGSFPP WPAVVFPQRL LRNDVYRKRK SNCVAVCFFN DPTYYWEQPS  60
   61 RLKELDQDSI HNFILEHSKN ANQRELVNAY KEAKNFDDFN VFLQEKFEEE NRLSDLKAFE 120
  121 KSEGSKIVAG EDPFVGRTKV VNKRKKNSIS IKEDPEDNQK SNEEESKPNI KPSKKKRPTA 180
  181 NSGGKSNSGN KKKVKLDYSR RVEISQLFRR RIQRNLIQRE TPPTEHEIKE THELLNRIYE 240
  241 NSDTKRPFFD LKALRESKLH KLLKAIVNDP DLGEFHPLCK EILLSWADLI TELKKEKLQA 300
  301 LPTP

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) SAS3 TOP2 YLR455W

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run None Entered #17 Mitotic Prep3-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data YLR455W Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..83] PSI-BLAST 22.045757 DNA methyltransferase DNMT3B
    2 View Details [84..145] PSI-BLAST 22.045757 DNA methyltransferase DNMT3B
    3 View Details [146..242] MSA 1.038994 View MSA. No confident structure predictions are available.
    4 View Details [243..304] deduced N/A Confident ab initio structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  2.4854263045204 bayes_pls_golite062009
  • protein binding
    		•  1.51678357126614 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle