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Protein Overview: SLS1

General Information:
Name(s) found: SLS1 / YLR139C [SGD]
Description(s) found:
Found 29 descriptions.
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  • Mitochondrial membrane protein that coordinates expression of mitochondrially-encoded genes; may facilitate delivery of mRNA to membrane-bound translation machinery [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 643 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [IDALink to PubMed article]
    integral to membrane [IDALink to PubMed article]
    mitochondrial inner membrane [IDALink to PubMed article]
    mitochondrial nucleoid [IDALink to PubMed articleLink to PubMed article]
    Biological Process: aerobic respiration [IMPLink to PubMed article]
    translation [IMPLink to PubMed articleLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MWKFNKKLAR LTYRLYSSSG PSSPLHGKKK LPQNLKFVVL NPTQSGLVKN DQKQPRHRPS  60
   61 KKRSHKETGD NNLDFGSKLL VFEKQNSLDS ALNSIRLKKP TSASLPSLEY NALLQSLTSS 120
  121 YNRYQLREFI STHQPDSSSH LTHWKKSKLS QYIIEKIWNC QPISTPTTPT GIKSTSLTFQ 180
  181 FDSPREIFLL LITQNGKILT NFNKLGLTFI ISIQDNELTV KGSPSLLKYA EISLNKIWSN 240
  241 ITHENVRMYS LMPSKDVINL IQKETHTFFE YLPDLQMYKI SALSTKKISM AKVFLLNAVA 300
  301 SNPNTTQHHH TIASPALKTE LYPFNNTLEN LDWLNKSQDW ARLQSVVPKN CTDLMTPTEN 360
  361 ATPELTDAQV SQFESSLSKN IPSLSPSDSI SQSLSITLGH SLQSASFSSI FQPLIHKSFI 420
  421 SKLLNLPMYK ESSSSAVPVP VPLDQHLITN AHQSFIQLNF TPVPPTSGSS SSPFLQIWFE 480
  481 IDEFDNIVTT SMRPLLKLQE NSVILRTPQC QTDYKITSDY IQDLLPDFDQ TNPDAWLSEQ 540
  541 KGLQEFLLKS HWKLNKYQNL MKKINISLPD NLIQQYQLTD VLTHRVLNLR FPTNTAQDDK 600
  601 YIIQYSDISR GFLNNGSYRQ LDFINVNPSE TSLKTFINDV LSF

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) MTF2 SLS1 URH1
    View Details Gavin AC, et al. (2006) MTF2 SLS1

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run RPA135 No Comments Schneider, DA, et al. (2006)
    View Run MLP2 #14 Mitotic Prep2-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data SLS1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..643] deduced N/A No confident structure predictions are available.
    2 View Details [182..327] deduced N/A No confident structure predictions are available.
    3 View Details [328..439] deduced N/A No confident structure predictions are available.
    4 View Details [440..643] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.78

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle