Protein Overview: URH1

General Information:
Name(s) found:	URH1 / YDR400W [SGD]
Description(s) found: Found 20 descriptions. SHOW ALL	Uridine nucleosidase (uridine-cytidine N-ribohydrolase), cleaves N-glycosidic bonds in nucleosides; involved in the pyrimidine salvage and nicotinamide riboside salvage pathways [SGD]
Organism:	Saccharomyces cerevisiae
Length:	340 amino acids
Gene Ontology:
Cellular Component:	nucleus [IDA] cytoplasm [IDA]
Biological Process:	pyrimidine nucleoside catabolic process [IDA ] ER-associated protein catabolic process [IMP] pyrimidine salvage [IMP]
Molecular Function:	ribosylpyrimidine nucleosidase activity [IDA ]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTVSKIPIWL DCDPGHDDAI AILLGCFHPA FNLLGISTCF GNAPPENTDY NARSLLTAMG  60
   61 KAQAIPVYKG AQRPWKREPH YAPDIHGISG LDGTSLLPKP TFEARTDKTY IEAIEEAILA 120
  121 NNGEISFVST GALTTLATVF RCKPYLKKSV KYISIMGGGL HGLGNCNPNL SAEFNVWIDP 180
  181 DAANYIFRDP DVKDKCIVVP LNLTHKAIAT YKVNEMIYNE KNNSKLRELF LELFQFFAHT 240
  241 YKDMQGFESG PPIHDPVALM PLLEFYGWDP SSAVGFRYKR MDISCIDDVF NENSGKIIIE 300
  301 KEYPNDSDVG TIIGLDLNIQ YFWDQIFEAL NRADKMSTIG

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	Riffle et al. (2010) (Unpublished Data)		PRE1 PRE10 PRE3 PRE5 PRE6 PRE8 PRE9 PUP2 PUP3 SCL1 URH1
View Details	Krogan NJ, et al. (2006)		MTF2 SLS1 URH1

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	MVP1	URH1	2	Unpublished Fields Lab Data

Microscopy / Localization Data

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	PROTEIN(S)	PUBLICATION
View Data	URH1	Huh WK, et al. (2003)

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..340]	PSI-BLAST	81.154902	Nucleoside hydrolase

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.90

Source: Reynolds et al. (2008)

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2