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Protein Overview: YLL058W

General Information:
Name(s) found: YLL058W [SGD]
Description(s) found:
Found 24 descriptions.
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  • Putative protein of unknown function with similarity to Str2p, which is a cystathionine gamma-synthase important in sulfur metabolism; YLL058W is not an essential gene [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 575 amino acids

    Gene Ontology:
    Cellular Component: cellular_component [ND]
    Biological Process: sulfur metabolic process [ISSLink to PubMed article]
    Molecular Function: cystathionine gamma-synthase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTEIEFGQPL PSNLDYAVSF GIPTWDSAIG YAEKVPEVIG KMATGYPRYF PQPPVQRLCA  60
   61 YFVKKFGRGS ENCRPFPSVN LGLKCFEYVK SVSGPESKAH LEVETVTIKN RGAKTSKEPA 120
  121 ELVLTIAAVL ASEEEFETVK EYWKLRGECV SSRLALSVNQ LLDCANHGSE QVLRELEAGV 180
  181 FAAKKGEEKA KNLIKGRIVE NRFRPFGLEK KTPNWEGLNL NPNEDVYLVS SGMSAISTAR 240
  241 NLLTFWEEKK NSGDSLNKTT SDQKKKPLLC DTVGIFGFPF KDTQVIMTKF GKCKFFGFGN 300
  301 SRDVVELQKF LETSKQRILA VFVETPSNPL LNMPDLKKLR SLADQYGFFI VIDDTIGGLN 360
  361 VDILPYADIV STSLTKLFNG ASNVMGGSVV LNPKSSLYPY AREYFRSANF EDLLWCEDAI 420
  421 VLERNSRDFE DRTLRANANT GILLNDLLLP EEGKICKKIY YPTVTSKETF ENYESVRNER 480
  481 GGYGCLFSVA FFNEGDAKAF YDSLKVFKGP SNGTNFTLAC PYVHLAHHSE LEEVSKFGAD 540
  541 PNIIRVSVGL EDIQWLLKVF SSALDVVKSR GSKHS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run RPA135 No Comments Schneider, DA, et al. (2006)
    View Run MLP2 #32 Asynchronous Prep-No Phosphopeptide enrichment Keck JM, et al. (2011)
    View Run MLP2 #29 Asynchronous Prep5-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..95] deduced N/A No confident structure predictions are available.
    2 View Details [96..433] PSI-BLAST 208.228787 Methionine gamma-lyase, MGL
    3 View Details [434..575] PSI-BLAST 208.228787 Methionine gamma-lyase, MGL

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • catalytic activity
    		•  2.29878871754893 bayes_pls_golite062009
  • L-aspartate:2-oxoglutarate aminotransferase activity
    		•  1.87460342369605 bayes_pls_golite062009
  • glycine dehydrogenase (decarboxylating) activity
    		•  1.80372125032222 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor
    		•  1.80372125032222 bayes_pls_golite062009
  • transferase activity
    		•  1.44093490824786 bayes_pls_golite062009
  • transferase activity, transferring nitrogenous groups
    		•  1.28316822767388 bayes_pls_golite062009
  • transaminase activity
    		•  1.24990480711889 bayes_pls_golite062009
  • carbon-sulfur lyase activity
    		•  0.698312655247044 bayes_pls_golite062009
  • cystathionine beta-lyase activity
    		•  0.6849039330512 bayes_pls_golite062009
  • binding
    		•  0.536634592992536 bayes_pls_golite062009
  • cystathionine gamma-lyase activity
    		•  0.505859361763689 bayes_pls_golite062009
  • glycine hydroxymethyltransferase activity
    		•  0.271623203801431 bayes_pls_golite062009
  • O-phospho-L-serine:2-oxoglutarate aminotransferase activity
    		•  0.234399054481664 bayes_pls_golite062009
  • pyridoxal phosphate binding
    		•  0.16957228630576 bayes_pls_golite062009
  • vitamin B6 binding
    		•  0.16957228630576 bayes_pls_golite062009
  • adenosylmethionine-8-amino-7-oxononanoate transaminase activity
    		•  0.0669652799570574 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.013097682076602 bayes_pls_golite062009
    3 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle