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Protein Overview: VBA5

General Information:
Name(s) found: VBA5 / YKR105C [SGD]
Description(s) found:
Found 26 descriptions.
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  • Putative transporter of the Major Facilitator Superfamily (MFS); proposed role as a basic amino acid permease based on phylogeny [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 582 amino acids

    Gene Ontology:
    Cellular Component: cellular_component [ND]
    Biological Process: biological_process [ND]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEETKYSSQQ EIEGACGSDA SLNARGSNDS PMGLSLYLCL ASLTLVLFIT ALDILIVGTI  60
   61 IDVVAEQFGN YSKTGWLVTG YSLPNAILSL IWGRFASIIG FQHSLILAIL IFEAGSLIAA 120
  121 LASSMNMLIF GRVVAGVGGS GLQTLCFVIG CTMVGERSRP LVISILSCAF AVAAIVGPII 180
  181 GGAFTTHVTW RWCFYINLPI GGLAIIMFLL TYKAENKGIL QQIKDAIGTI SSFTFSKFRH 240
  241 QVNFKRLMNG IIFKFDFFGF ALCSAGLVLF LLGLTFGGNK YSWNSGQVIT YLVLGVLLFI 300
  301 FSLVYDFFLF DKFNPEPDNI SYRPLLLRRL VAKPAIIIVN MVTFLLCTGY NGQMIYSVQF 360
  361 FQLIFASSAW KAGLHLIPIV ITNVIAAIAS GVITKKLGLV KPLLIFGGVL GVIGAGLMTL 420
  421 MTNTSTKSTQ IGVLLLPGFS LGFALQASLM SAQLQITKDR PEAAMDFIEV TAFNTFMKSL 480
  481 GTTLGGVLST TVFSASFHNK VSRAHLEPYE GKTVDDMILY RLQNYDGSHS TIGNILSDSI 540
  541 KNVFWMDLGF YALGFLFCSF SSNKKLIIPK KDDTPEDNLE DK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run CEP3 sample cbf3 from feb 2005 Sandall S, et all (2006)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..242] PSI-BLAST 9.154902 No description for 1lviA_ was found.
    2 View Details [243..314] deduced N/A No confident structure predictions are available.
    3 View Details [315..526] MSA 7.705997 View MSA. No confident structure predictions are available.
    4 View Details [527..582] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • transporter activity
    		•  4.09176719149278 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  3.59744164024479 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  3.5865018981083 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  3.54194478414824 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  2.21266150105753 bayes_pls_golite062009
  • organic acid transmembrane transporter activity
    		•  2.15783210522667 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  1.79369588808394 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  1.59419818573076 bayes_pls_golite062009
  • secondary active transmembrane transporter activity
    		•  1.22264637452409 bayes_pls_golite062009
  • binding
    		•  1.01584233411372 bayes_pls_golite062009
  • polyol transmembrane transporter activity
    		•  0.924836669821548 bayes_pls_golite062009
  • alcohol transmembrane transporter activity
    		•  0.924836669821548 bayes_pls_golite062009
  • glycerol transmembrane transporter activity
    		•  0.812001619402678 bayes_pls_golite062009
  • symporter activity
    		•  0.74591237387473 bayes_pls_golite062009
  • solute:cation symporter activity
    		•  0.74591237387473 bayes_pls_golite062009
  • cation:sugar symporter activity
    		•  0.143419068761182 bayes_pls_golite062009
  • sugar:hydrogen symporter activity
    		•  0.143419068761182 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle