YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: MSN4

General Information:
Name(s) found: MSN4 / YKL062W [SGD]
Description(s) found:
Found 29 descriptions.
SHOW ALL
  • Transcriptional activator related to Msn2p; activated in stress conditions, which results in translocation from the cytoplasm to the nucleus; binds DNA at stress response elements of responsive genes, inducing gene expression [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 630 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytoplasm [IDALink to PubMed article]
    Biological Process: response to oxidative stress [IGILink to PubMed article]
    response to hydrostatic pressure [IGILink to PubMed article]
    heat acclimation [IMPLink to PubMed article]
    regulation of transcription from RNA polymerase II promoter in response to stress [IMPLink to PubMed article]
    response to osmotic stress [IGILink to PubMed article]
    response to freezing [IGILink to PubMed article]
    replicative cell aging [IMPLink to PubMed article]
    age-dependent response to oxidative stress involved in chronological cell aging [IMPLink to PubMed article]
    response to stress [IMPLink to PubMed article]
    cellular response to glucose starvation [IMPLink to PubMed article]
    Molecular Function: transcription factor activity [IDALink to PubMed article][IMPLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLVFGPNSSF VRHANKKQED SSIMNEPNGL MDPVLSTTNV SATSSNDNSA NNSISSPEYT  60
   61 FGQFSMDSPH RTDATNTPIL TATTNTTANN SLMNLKDTAS LATNWKWKNS NNAQFVNDGE 120
  121 KQSSNANGKK NGGDKIYSSV ATPQALNDEL KNLEQLEKVF SPMNPINDSH FNENIELSPH 180
  181 QHATSPKTNL LEAEPSIYSN LFLDARLPNN ANSTTGLNDN DYNLDDTNND NTNSMQSILE 240
  241 DFVSSEEALK FMPDAGRDAR RYSEVVTSSF PSMTDSRNSI SHSIEFWNLN HKNSSNSKPT 300
  301 QQIIPEGTAT TERRGSTISP TTTINNSNPN FKLLDHDVSQ ALSGYSMDFS KDSGITKPKS 360
  361 ISSSLNRISH SSSTTRQQRA SLPLIHDIES FANDSVMANP LSDSASFLSE ENEDDAFGAL 420
  421 NYNSLDATTM SAFDNNVDPF NILKSSPAQD QQFIKPSMML SDNASAAAKL ATSGVDNITP 480
  481 TPAFQRRSYD ISMNSSFKIL PTSQAHHAAQ HHQQQPTKQA TVSPNTRRRK SSSVTLSPTI 540
  541 SHNNNNGKVP VQPRKRKSIT TIDPNNYDKN KPFKCKDCEK AFRRSEHLKR HIRSVHSTER 600
  601 PFACMFCEKK FSRSDNLSQH LKTHKKHGDF

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Ho Y, et al. (2002) GET2 GET3 MSN4

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run DAD1 Dam1-765 complex purified from yeast with Dad1-TAP Shimogawa MM, et al. (2006)
    View Run RLF2 phosphorylation data - cascade search Green EM, et al (2005)
    View Run ZDS1 Sample 2- cpn2 from june 2005 McCusker D, et al (2007)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..212] MSA 4.390995 View MSA. No confident structure predictions are available.
    2 View Details [213..349] MSA 20.919997 View MSA. No confident structure predictions are available.
    3 View Details [350..460] PSI-BLAST 32.218487 Transcription factor IIIA, TFIIIA
    4 View Details [461..557] PSI-BLAST 128.09691 ZIF268
    5 View Details [558..630] PSI-BLAST 130.30103 ZIF268


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle