Protein Overview: YJR129C

General Information:
Name(s) found:	YJR129C [SGD]
Description(s) found: Found 24 descriptions. SHOW ALL	Putative protein of unknown function; predicted S-adenosylmethionine-dependent methyltransferase of the seven beta-strand family; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm [SGD]
Organism:	Saccharomyces cerevisiae
Length:	339 amino acids
Gene Ontology:
Cellular Component:	cytoplasm [IDA]
Biological Process:	biological_process [ND]
Molecular Function:	S-adenosylmethionine-dependent methyltransferase activity [ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNEDLFYDRL HQRCPGKYLL EELETSKSND VLHASRFVCE MELVQKTNAY YCKTIVKMLL  60
   61 DHEWIFAKAF TIVNDGEDEI EIYDYLYEKY IKLLSTGKPD PMMKDVVRYR FDEDVKITIE 120
  121 ETPNLISAAS TTGFRTWEAA LYMGDFLIHK PLQELAPVQG QDDGKKKLNV LEVGAGTGIV 180
  181 SLVILQKYHE FVNKMYVTDG DSNLVETQLK RNFELNNEVR ENEPDIKLQR LWWGSDRVPE 240
  241 DIDLVVGADV TYDPTILPDL CECLAECLAL DRCKLCLLSA TIRSESTVQL FSQECNKLGL 300
  301 KCTIVTSTEY DANNEIRAMK ALQFKPLIAP IRIYKITKQ

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	YDL121C	YJR129C	1	Unpublished Fields Lab Data
View Screen	CDC53	YJR129C	1	Unpublished Fields Lab Data
View Screen	FAR10	YJR129C	1	Unpublished Fields Lab Data

Microscopy / Localization Data

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	PROTEIN(S)	PUBLICATION
View Data	YJR129C	Huh WK, et al. (2003)

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..121]	MSA	2.164993	View MSA. No confident structure predictions are available.
2	View Details	[122..339]	PSI-BLAST	21.30103	Arginine methyltransferase, HMT1

Functions predicted (by domain):

Gene Ontology predictions

Term	Confidence	Notes
methyltransferase activity	3.57681394097837	bayes_pls_golite062009
transferase activity, transferring one-carbon groups	3.49392219433935	bayes_pls_golite062009
S-adenosylmethionine-dependent methyltransferase activity	3.39429041855776	bayes_pls_golite062009
RNA methyltransferase activity	3.07428840534971	bayes_pls_golite062009
rRNA methyltransferase activity	2.5924681776558	bayes_pls_golite062009
transferase activity	2.22303238506686	bayes_pls_golite062009
catalytic activity	1.25333584501255	bayes_pls_golite062009
tRNA methyltransferase activity	1.12859857407629	bayes_pls_golite062009
N-methyltransferase activity	0.891400969900644	bayes_pls_golite062009
rRNA (adenine) methyltransferase activity	0.794703281700029	bayes_pls_golite062009
rRNA (adenine-N6,N6-)-dimethyltransferase activity	0.716476158062361	bayes_pls_golite062009
protein methyltransferase activity	0.348134584790547	bayes_pls_golite062009
rRNA (guanine) methyltransferase activity	0.0854264678700428	bayes_pls_golite062009

No functions predicted.

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Source: Reynolds et al. (2008)

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2