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View Structure Prediction Details

Protein: YJR129C
Organism: Saccharomyces cerevisiae
Length: 339 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YJR129C.

Description E-value Query
Range
Subject
Range
YJR129C - Putative protein of unknown function; predicted S-adenosylmethionine-dependent methyltransferase of ...
6.0E-77 [1..339] [1..339]
gi|14603247, gi|... - gi|14603247|gb|AAH10084.1| Family with sequence similarity 86, member A [Homo sapiens], gi|119605642...
3.0E-56 [15..310] [30..312]
gi|7228478 - gb|AAF42473.1| actinomycin synthetase III [Streptomyces chrysomallus]
gi|7228478 - gi|7228478|gb|AAF42473.1|AF204401_1 actinomycin synthetase III [Streptomyces chrysomallus]
1.0E-31 [55..298] [1935..2165]
gi|15029321 - gi|15029321|gb|AAK81826.1| peptide synthetase [Streptomyces lavendulae]
9.0E-31 [47..298] [3864..4112]
gi|18920646 - gi|18920646|gb|AAL82382.1| McyA [Microcystis aeruginosa]
2.0E-30 [63..313] [682..936]
gi|6007553 - gi|6007553|gb|AAF00960.1| McyA [Microcystis aeruginosa PCC 7806]
gi|6007553 - gi|6007553|gb|AAF00960.1|AF183408_8 McyA [Microcystis aeruginosa PCC 7806]
5.0E-29 [63..313] [674..928]

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Predicted Domain #1
Region A:
Residues: [1-121]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNEDLFYDRL HQRCPGKYLL EELETSKSND VLHASRFVCE MELVQKTNAY YCKTIVKMLL  60
   61 DHEWIFAKAF TIVNDGEDEI EIYDYLYEKY IKLLSTGKPD PMMKDVVRYR FDEDVKITIE 120
  121 E

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
methyltransferase activity 3.57681394097837 bayes_pls_golite062009
transferase activity, transferring one-carbon groups 3.49392219433935 bayes_pls_golite062009
S-adenosylmethionine-dependent methyltransferase activity 3.39429041855776 bayes_pls_golite062009
RNA methyltransferase activity 3.07428840534971 bayes_pls_golite062009
rRNA methyltransferase activity 2.5924681776558 bayes_pls_golite062009
transferase activity 2.22303238506686 bayes_pls_golite062009
catalytic activity 1.25333584501255 bayes_pls_golite062009
tRNA methyltransferase activity 1.12859857407629 bayes_pls_golite062009
N-methyltransferase activity 0.891400969900644 bayes_pls_golite062009
rRNA (adenine) methyltransferase activity 0.794703281700029 bayes_pls_golite062009
rRNA (adenine-N6,N6-)-dimethyltransferase activity 0.716476158062361 bayes_pls_golite062009
protein methyltransferase activity 0.348134584790547 bayes_pls_golite062009
rRNA (guanine) methyltransferase activity 0.0854264678700428 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [122-339]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TPNLISAAST TGFRTWEAAL YMGDFLIHKP LQELAPVQGQ DDGKKKLNVL EVGAGTGIVS  60
   61 LVILQKYHEF VNKMYVTDGD SNLVETQLKR NFELNNEVRE NEPDIKLQRL WWGSDRVPED 120
  121 IDLVVGADVT YDPTILPDLC ECLAECLALD RCKLCLLSAT IRSESTVQLF SQECNKLGLK 180
  181 CTIVTSTEYD ANNEIRAMKA LQFKPLIAPI RIYKITKQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 21.30103
Match: 1g6q1_
Description: Arginine methyltransferase, HMT1
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle