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Protein Overview: GON7

General Information:
Name(s) found: GON7 / YJL184W [SGD]
Description(s) found:
Found 33 descriptions.
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  • Protein proposed to be involved in the modification of N-linked oligosaccharides, osmotic stress response, telomere uncapping and elongation, transcription; component of the EKC/KEOPS protein complex with Kae1p, Cgi121p, Pcc1p, and Bud32p [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 123 amino acids

    Gene Ontology:
    Cellular Component: nuclear chromatin [IDALink to PubMed article]
    EKC/KEOPS protein complex [IDALink to PubMed articleLink to PubMed article]
    Biological Process: cell wall mannoprotein biosynthetic process [IMPLink to PubMed article]
    telomere maintenance [IMPLink to PubMed article]
    response to desiccation [IEPLink to PubMed article]
    positive regulation of transcription from RNA polymerase II promoter [IPILink to PubMed article]
    Molecular Function: chromatin DNA binding [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKLPVAQYSA PDGVEKSFAP IRDDPRYMTT EGRTTGPSDH VLNAGQIDRD KPSEPERTKD  60
   61 GSQLTYLGQL RTQLTGLQDD INEFLTGRME LAKNKKKAGA DEKRIQEEIN QLLDGGDGDE 120
  121 DAV

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) CGI121 GON7 KAE1
    View Details Hazbun TR, et al. (2003) GON7 KAE1
    View Details Krogan NJ, et al. (2006) CGI121 GON7 KAE1
    View Details Gavin AC, et al. (2006) CGI121 GON7 KAE1
    View Details Qiu et al. (2008) CGI121 GON7 KAE1 PCC1 TBF1

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run KAE1 No Comments Hazbun TR, et al. (2003)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen FAR3 GON7 2 Unpublished Fields Lab Data

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..123] Pfam 67.008774 No description for PF08738.1 was found. No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle