Protein Overview: MNN11

General Information:
Name(s) found:	MNN11 / YJL183W [SGD]
Description(s) found: Found 17 descriptions. SHOW ALL	Subunit of a Golgi mannosyltransferase complex that also contains Anp1p, Mnn9p, Mnn10p, and Hoc1p, and mediates elongation of the polysaccharide mannan backbone; has homology to Mnn10p [SGD]
Organism:	Saccharomyces cerevisiae
Length:	422 amino acids
Gene Ontology:
Cellular Component:	alpha-1,6-mannosyltransferase complex [IPI]
Biological Process:	protein amino acid glycosylation [IDA][IMP]
Molecular Function:	alpha-1,6-mannosyltransferase activity [IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAIKPRTKGK TYSSRSVGSQ WFNRLGFKQN KYGTCKFLSI ITAFVFILYF FSNRFYPISR  60
   61 SAGASYSPSH GLYINEIPAS SRLIYPHVEH VPVLKQMTVR GLYITRLEVD GSKRLILKPE 120
  121 ENALTDEEKK KTTDQILLVK HSFLDHGKLV YRKSNDAPEV VVVTLIDFEN YELETIIQIV 180
  181 QNRVDYAQKH QYGVYIRWIQ EFLPVLENQN LAESYEFIKP LVIRAAMHAF PTAKYIHFVD 240
  241 QDALLMNLDL SLQKYLLDPK IMDLALLKNV PVVANSNIKT YNHFEYSSAK IIIPHDAGGN 300
  301 IDASSFVIAN DFYGKALIDY LNDPLLRNFP WDNTGDKLSA AIGHILQWHP TLLGKTAIVI 360
  361 PKVLASQYDA SLDQEGESGN GASNGDVYHY NEGDLAASFK GCRSRGTCAS EIGHMYQKIK 420
  421 KS

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	Riffle et al. (2010) (Unpublished Data)		ANP1 HOC1 MNN10 MNN11 MNN9 PHB1 PHB2
View Details	Gavin AC, et al. (2006)		ANP1 HOC1 MNN10 MNN11 MNN9
View Details	Qiu et al. (2008)		ANP1 GDA1 GLO3 GNT1 HOC1 MNN1 MNN10 MNN11 MNN5 MNN9 OCH1 SEC22 VAN1 VRG4

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	VAM3	Sample: HX12 - trans-SNARE complex formation and fusion are inhibited (control).	Hao Xu, et al. (2010)

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	UBC12	MNN11	1	Unpublished Fields Lab Data

Microscopy / Localization Data

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	PROTEIN(S)	PUBLICATION
View Data	MNN11 and ANP1	Huh WK, et al. (2003)
View Data	MNN11	Huh WK, et al. (2003)

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..87]	deduced	N/A	No confident structure predictions are available.
2	View Details	[88..422]	MSA	13.017942	View MSA. No confident structure predictions are available.
3	View Details	[232..422]	FFAS03	2.41	No description for 2p6wA was found.

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

[View Details]

Source: Reynolds et al. 2008. Manuscript submitted

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2