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Protein Overview: MRS3

General Information:
Name(s) found: MRS3 / YJL133W [SGD]
Description(s) found:
Found 37 descriptions.
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  • Iron transporter that mediates Fe2+ transport across the inner mitochondrial membrane; mitochondrial carrier family member, similar to and functionally redundant with Mrs4p; active under low-iron conditions; may transport other cations [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 314 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [IDALink to PubMed article]
    Biological Process: RNA splicing [IGILink to PubMed article]
    mitochondrial transport [ISSLink to PubMed article]
    mitochondrial iron ion transport [IDALink to PubMed article]
    Molecular Function: iron ion transmembrane transporter activity [IMPLink to PubMed article]
    surfactant activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVENSSSNNS TRPIPAIPMD LPDYEALPTH APLYHQLIAG AFAGIMEHSV MFPIDALKTR  60
   61 IQSANAKSLS AKNMLSQISH ISTSEGTLAL WKGVQSVILG AGPAHAVYFG TYEFCKKNLI 120
  121 DSSDTQTHHP FKTAISGACA TTASDALMNP FDTIKQRIQL NTSASVWQTT KQIYQSEGLA 180
  181 AFYYSYPTTL VMNIPFAAFN FVIYESSTKF LNPSNEYNPL IHCLCGSISG STCAAITTPL 240
  241 DCIKTVLQIR GSQTVSLEIM RKADTFSKAA SAIYQVYGWK GFWRGWKPRI VANMPATAIS 300
  301 WTAYECAKHF LMTY

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details (MIPS) Mewes HW, et al. (2004) BI4 CBP6 MRS1 MRS2 MRS3 MRS4 MSS1 MSS116 MSS18 MTF2 NAM2 PET54 TIM10
    View Details Qiu et al. (2008) BI4 MRS1 MRS2 MRS3 MRS4 MSS116

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen YCK1 MRS3 1 Unpublished Fields Lab Data
    View Screen ATG5 MRS3 1 Unpublished Fields Lab Data

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data MRS3 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..314] ORFEUS 7.42 Peroxisomal acyl-CoA oxidase-II, domains 3 and 4; Peroxisomal acyl-CoA oxidase-II, domains 1 and 2


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.50

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle