Protein Overview: RRD1

General Information:
Name(s) found:	RRD1 / YIL153W [SGD]
Description(s) found: Found 24 descriptions. SHOW ALL	Peptidyl-prolyl cis/trans-isomerase, activator of the phosphotyrosyl phosphatase activity of PP2A; involved in G1 phase progression, microtubule dynamics, bud morphogenesis and DNA repair; subunit of the Tap42p-Sit4p-Rrd1p complex [SGD]
Organism:	Saccharomyces cerevisiae
Length:	393 amino acids
Gene Ontology:
Cellular Component:	nucleus [IDA] cytoplasm [IDA] cell fraction [IDA]
Biological Process:	DNA repair [IDA][IMP] response to osmotic stress [IGI][IMP] mitotic spindle organization in nucleus [IMP]
Molecular Function:	protein phosphatase type 2A regulator activity [IGI][IMP][ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLDRVDWPH ATFSTPVKRI FDTQTTLDFQ SSLAIHRIKY HLHKYTTLIS HCSDPDPHAT  60
   61 ASSIAMVNGL MGVLDKLAHL IDETPPLPGP RRYGNLACRE WHHKLDERLP QWLQEMLPSE 120
  121 YHEVVPELQY YLGNSFGSST RLDYGTGHEL SFMATVAALD MLGMFPHMRG ADVFLLFNKY 180
  181 YTIMRRLILT YTLEPAGSHG VWGLDDHFHL VYILGSSQWQ LLDAQAPLQP REILDKSLVR 240
  241 EYKDTNFYCQ GINFINEVKM GPFEEHSPIL YDIAVTVPRW SKVCKGLLKM YSVEVLKKFP 300
  301 VVQHFWFGTG FFPWVNIQNG TDLPVFEEKE EESIEQANAG SPGREQTSTR FPTSTSMPPP 360
  361 GVPPSGNNIN YLLSHQNQSH RNQTSFSRDR LRR

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	Krogan NJ, et al. (2006)		ABF2 ARG82 CKI1 CMR1 HHF1, HHF2 HTA1 HTA2 HTB1 HTB2 NUP188 PPH3 PSY2 PSY4 RRD1 SLX5 SLX8 SPT5 STP1 TOP2

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

	PROTEIN(S)	PUBLICATION
View Data	RRD1	Huh WK, et al. (2003)

Searching the YRC Public Image Repository, found results:

Currently showing to of results.

[View Search in the YRC Public Image Repository]

Searching the YRC Public Image Repository, found no results.

Ginzu Version Information

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

Gene Ontology predictions

Term	Confidence	Notes
binding	1.8791829282582	bayes_pls_golite062009
enzyme regulator activity	1.7601888817048	bayes_pls_golite062009
phosphatase regulator activity	1.33200954243368	bayes_pls_golite062009
protein phosphatase regulator activity	1.2842291535489	bayes_pls_golite062009
enzyme activator activity	0.877491580866805	bayes_pls_golite062009
phosphatase activator activity	0.566631939970268	bayes_pls_golite062009
protein binding	0.492511638812294	bayes_pls_golite062009
catalytic activity	0.262417313750414	bayes_pls_golite062009
protein phosphatase type 2A regulator activity	0.132873007056084	bayes_pls_golite062009

No functions predicted.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.94

Source: Reynolds et al. (2008)

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..337]	Pfam	209.508638	Phosphotyrosyl phosphate activator (PTPA) protein No confident structure predictions are available.
2	View Details	[338..393]	deduced	N/A	No confident structure predictions are available.

Protein Overview: RRD1

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: