Protein Overview: POG1

General Information:
Name(s) found:	POG1 / YIL122W [SGD]
Description(s) found: SHOW ONLY BEST	gi\|731866\|sp\|P40473.1\|POG1_YEAST RecName: Full=Transcriptional acticator POG1; AltName: Full=Promoter of growth protein 1 [NCBI NR] gi\|6322069\|ref\|NP_012144.1\| Putative transcriptional activator that promotes recovery from pheromone induced arrest; inhibits both alpha-factor induced G1 arrest and repression of CLN1 and CLN2 via SCB/MCB promoter elements; potential Cdc28p substrate; SB [NCBI NR] gi\|599995\|emb\|CAA86870.1\| unknown [Saccharomyces cerevisiae] [NCBI NR] pir\|\|S49887 hypothetical protein YIL122w - yeast (Saccharomyces cerevisiae) [NCBI NR] Uncharacterized protein YIL122W - Saccharomyces cerevisiae (Baker's yeast) [Swiss-Prot] Transcriptional acticator POG1 OS=Saccharomyces cerevisiae GN=POG1 PE=1 SV=1 [Swiss-Prot] POG1 Promotes recovery from pheromone arrest via the G1 cyclin CLN2 [mips] Putative transcriptional activator that promotes recovery from pheromone induced arrest; inhibits both alpha-factor induced G1 arrest and repression of CLN1 and CLN2 via SCB/MCB promoter elements; potential Cdc28p substrate; SBF regulated [SGD] YIL122W, Chr IX from 130607-131662 [yeast_orfs2] Chr IX from 130607-131662 [yeastorf3.fasta] (P40473) Hypothetical 39.5 kDa protein in SIM1-RPI1 intergenic region [4932.FASTACCERV.txt] POG1 SGDID:S0001384, Chr IX from 130607-131662, Verified ORF [yeastflysequest.fasta] Pog1p [Saccharomyces cerevisiae]gi\|599995\|emb\|CAA86870.1\| unknown [Saccharomyces cerevisiae]gi\|731866\|sp\|P40473\|YIM2_YEAST Hypothetical 39.5 kDa protein in SIM1-RPI1 intergenic regiongi\|1077758\|pir\|\|S49887 hypothetical protein YIL122w - yeast (Saccharo [nrdb_11152004_Chlamydomonas] POG1 SGDID:S000001384, Chr IX from 130607-131662, Verified ORF, "Putative transcriptional activator that promotes recovery from pheromone induced arrest; inhibits both alpha-factor induced G1 arrest and repression of CLN1 and CLN2 via SCB/MCB promoter ele [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta] Uncharacterized protein YIL122W [nr-271106-contam.fasta] unknown [Saccharomyces cerevisiae] [nr-271106-contam.fasta] Putative transcriptional activator that promotes recovery from pheromone induced arrest; inhibits both alpha-factor induced G1 arrest and repression of CLN1 and CLN2 via SCB/MCB promoter elements; potential Cdc28p substrate; SBF regulated; Pog1p [Saccharo [nr-271106-contam.fasta] POG1 SGDID:S000001384, Chr IX from 130607-131662, Verified ORF, "Putative transcriptional activator that promotes recovery from pheromone induced arrest; inhibits both alpha-factor induced G1 arrest and repression of CLN1 and CLN2 via SCB/MCB promoter elements; potential Cdc28p substrate; SBF regulated" [yeast-bovrabprots.fasta] [chemostatdb.fasta] Transcriptional acticator POG1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=POG1 PE=1 SV=1 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta] POG1 SGDID:S000001384, Chr IX from 130610-131665, Genome Release 64-1-1, Verified ORF, "Nuclear chromatin-associated protein of unknown function; overexpression promotes recovery from pheromone induced arrest and suppresses the stress sensitivity caused by a mutation in the E3 ubiquitin ligase Rsp5p; binds upstream of BAR1 and cell cycle-related genes; potential Cdc28p substrate; SBF regulated" [yeast-030211-contam.fasta] Transcriptional activator POG1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=POG1 PE=1 SV=1 [YEAST.fasta.20131015] POG1 SGDID:S000001384, Chr IX from 130610-131665, Genome Release 64-2-1, Verified ORF, "Nuclear chromatin-associated protein of unknown function; may have a role in cell cycle regulation; overexpression promotes recovery from pheromone induced arrest and suppresses the stress sensitivity caused by a mutation in the E3 ubiquitin ligase Rsp5p; binds upstream of BAR1 and cell cycle-related genes; phsosphoylated form may be ubiquitinated by Dma2p; potential Cdc28p substrate; SBF regulated" [20141208_orf_trans.fasta] YIL122W SGDID:S000001384, Chr IX from 130610-131665, Genome Release 64-1-1, Verified ORF, "Nuclear chromatin-associated protein of unknown function; overexpression promotes recovery from pheromone induced arrest and suppresses the stress sensitivity caused by a mutation in the E3 ubiquitin ligase Rsp5p; binds upstream of BAR1 and cell cycle-related genes; potential Cdc28p substrate; SBF regulated" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
Organism:	Saccharomyces cerevisiae
Length:	351 amino acids
Gene Ontology:
Cellular Component:	nucleus [IDA ]
Biological Process:	regulation of transcription involved in G1/S-phase of mitotic cell cycle [IPI] re-entry into mitotic cell cycle after pheromone arrest [IGI][IMP]
Molecular Function:	specific RNA polymerase II transcription factor activity [ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKQEPHRQSE EKEKPKGPMA VEREQHTSLS SGTTVTASTG DESTNSRPVE SSQTEKSLSL  60
   61 RIRILKQLGF DDIQELNACD TGLVEQFLNV RLINDTKELE KIRESNLAKL NQIIDKCMES 120
  121 DKISDSTLNK ILDMSMNRDT NNDNNNHLTI PSPITTKKRK INASELASPR GHRRYRSDIP 180
  181 TVSEVETGVG YPQIHQQPGA YTLPMPANQW MSNPYMQPPQ PQVQQIMPQY LYPPGMGPQA 240
  241 QLPTMSSNSE SQTPVMSSQF LSLNQHGLYQ QNIGAHPVMS MGPQANIYGQ QHQLQPGQER 300
  301 DQSRKSFSHR RSQSANISMA NFRSPMRNPQ PASSQRPVNF LIHTPKHPPP T

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	RPA135	No Comments	Schneider, DA, et al. (2006)
View Run	MLP2	#24 Asynchronous Prep3-TiO2 Phosphopeptide enrichment	Keck JM, et al. (2011)
View Run	MLP2	#32 Asynchronous Prep-No Phosphopeptide enrichment	Keck JM, et al. (2011)

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	GTS1	POG1	2	Unpublished Fields Lab Data
View Screen	TEM1	POG1	1	Unpublished Fields Lab Data
View Screen	APC5	POG1	1	Unpublished Fields Lab Data

Microscopy / Localization Data

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	PROTEIN(S)	PUBLICATION
View Data	POG1	Huh WK, et al. (2003)

Protein Structure Data

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Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..351]	deduced	N/A	No confident structure predictions are available.

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Source: Reynolds et al. (2008)

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2